PMID- 35289552 OWN - NLM STAT- MEDLINE DCOM- 20220317 LR - 20220531 IS - 0023-1207 (Print) IS - 0023-1207 (Linking) IP - 3 DP - 2022 TI - [Endovascular interventions in patients with glass iii infrainguinal arterial disease: 2-year results]. PG - 70-78 LID - 10.17116/hirurgia202203170 [doi] AB - OBJECTIVE: To evaluate the results of endovascular surgery in patients with chronic limb-threatening ischemia (CLTI) with infrainguinal arterial disease GLASS III. MATERIAL AND METHODS: Treatment outcomes were analyzed for the period 2017-2018. Inclusion criteria were age over 18 years, CLTI, extended (>20 cm) stenosis de novo and occlusion of femoropopliteal segment (FPS) combined with occlusive lesion of tibial arteries. We analyzed 147 patients divided into 2 groups depending on stenting strategy. FPS-1-TA included 53 patients who underwent angioplasty (+/- stenting) of femoropopliteal arteries and lower leg arteries resulted at least one patent tibial artery. FPS-2-TA enrolled 94 patients who underwent angioplasty of femoropopliteal arteries and lower leg arteries resulted >/=2 patent tibial arteries. Mean age was 71.0+/-9.8 years. There were 75 men. Demographics and clinical characteristics of patients were similar. RESULTS: Technical success rate was 100%. Mean length of stenting was 203 +/- 99 mm. Occlusion of all 3 leg arteries correlated with high incidence of femoropopliteal stenting. In the FPS-1-TA group, stents were implanted in 39 patients, in the FPS-2-TA group - in 71 patients (73.6% and 75.5%, respectively, p=0.8). Braided nitinol stents were used for stenting of the lower third of superficial femoral artery and p1-p3 segments. Mean follow-up period was 22.6+/-1.1 months. Two-year results were not age-specific in our study. Kaplan-Meier overall survival, freedom from amputation and amputation-free survival for the entire sample were 79.6%, 81.0%, and 66.7%, respectively. We compared these values in both groups using Mantel-Cox log-rank test and obtained significant differences (67.9% vs 86.2%, p=0.004; 64.2% vs 90%, p<0.0001; 47.2% vs 77.7%, p<0.0001, respectively). CONCLUSION: Our results are comparable with literature data regarding freedom from amputation and amputation-free survival. We obtained significant differences in overall survival and freedom from amputation depending on endovascular strategy for tibial arteries. Correction of distal vessels with recanalization of at least two tibial arteries is advisable for endovascular treatment of diffuse complex lesions. FAU - Tarabrin, A S AU - Tarabrin AS AUID- ORCID: 0000-0002-7386-2141 AD - Bauman Moscow City Hospital No. 29, Moscow, Russia. AD - People' Friendship University of Russia, Moscow, Russia. FAU - Maksimkin, D A AU - Maksimkin DA AUID- ORCID: 0000-0002-3593-436X AD - People' Friendship University of Russia, Moscow, Russia. FAU - Pavkina, A A AU - Pavkina AA AUID- ORCID: 0000-0002-1933-2131 AD - Pirogov Russian National Research Medical University, Moscow, Russia. FAU - Khovalkin, R G AU - Khovalkin RG AUID- ORCID: 0000-0001-7826-4768 AD - Bauman Moscow City Hospital No. 29, Moscow, Russia. FAU - Zheltov, N Yu AU - Zheltov NY AUID- ORCID: 0000-0003-1104-1126 AD - Bauman Moscow City Hospital No. 29, Moscow, Russia. FAU - Shugushev, Z Kh AU - Shugushev ZK AUID- ORCID: 0000-0002-5335-5062 AD - People' Friendship University of Russia, Moscow, Russia. LA - rus PT - Journal Article TT - Endovaskulyarnye interventsii u patsientov s infraingvinal'nymi porazheniyami GLASS III stepeni: rezul'taty dvukhletnego nablyudeniya. PL - Russia (Federation) TA - Khirurgiia (Mosk) JT - Khirurgiia JID - 0412765 SB - IM MH - Aged MH - Aged, 80 and over MH - Angioplasty/adverse effects MH - Female MH - Femoral Artery/diagnostic imaging/surgery MH - Humans MH - Male MH - Middle Aged MH - *Peripheral Arterial Disease/diagnosis/surgery MH - *Popliteal Artery/diagnostic imaging/surgery MH - Vascular Patency OTO - NOTNLM OT - CLTI OT - GLASS OT - WIfI OT - angioplasty of lower leg arteries OT - diabetic foot OT - femoropopliteal bypass grafting OT - femoropopliteal segment OT - infrainguinal angioplasty OT - stenting EDAT- 2022/03/16 06:00 MHDA- 2022/03/18 06:00 CRDT- 2022/03/15 09:48 PHST- 2022/03/15 09:48 [entrez] PHST- 2022/03/16 06:00 [pubmed] PHST- 2022/03/18 06:00 [medline] AID - 10.17116/hirurgia202203170 [doi] PST - ppublish SO - Khirurgiia (Mosk). 2022;(3):70-78. doi: 10.17116/hirurgia202203170.