PMID- 35295527
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220319
IS  - 2673-561X (Electronic)
IS  - 2673-561X (Print)
IS  - 2673-561X (Linking)
VI  - 2
DP  - 2021
TI  - Factors Associated With Clinical Responses to Spinal Manipulation in Patients 
      With Non-specific Thoracic Back Pain: A Prospective Cohort Study.
PG  - 742119
LID - 10.3389/fpain.2021.742119 [doi]
LID - 742119
AB  - Introduction: The management of musculoskeletal disorders is complex and requires 
      a multidisciplinary approach. Manual therapies, such as spinal manipulative 
      therapy (SMT), are often recommended as an adjunct treatment and appear to have 
      demonstrable effects on pain and short-term disability in several spinal 
      conditions. However, no definitive mechanism that can explain these effects has 
      been identified. Identifying relevant prognostic factors is therefore recommended 
      for people with back pain. Objective: The main purpose of this study was to 
      identify short-term candidate prognostic factors for clinically significant 
      responses in pain, disability and global perceived change (GPC) following a 
      spinal manipulation treatment in patients with non-specific thoracic back pain. 
      Methods: Patients seeking care for thoracic spine pain were invited to 
      participate in the study. Pain levels were recorded at baseline, 
      post-intervention, and 1 week after a single session of SMT. Disability levels 
      were collected at baseline and at 1-week follow-up. GPC was collected 
      post-intervention and at 1-week follow-up. Biomechanical parameters of SMT, 
      expectations for improvement in pain and disability, kinesiophobia, anxiety 
      levels as well as perceived comfort of spinal manipulative therapy were assessed. 
      Analysis: Differences in baseline characteristics were compared between patients 
      categorized as responders or non-responders based on their pain level, disability 
      level, and GPC at each measurement time point. Binary logistic regression was 
      calculated if the statistical significance level of group comparisons (responder 
      vs. non-responders) was equal to, or <0.2 for candidate prognostic factors. 
      Results: 107 patients (62 females and 45 males) were recruited. Mean peak force 
      averaged 450.8 N with a mean thrust duration of 134.9 ms. Post-intervention, 
      comfort was associated with pain responder status (p < 0.05) and GPC responder 
      status (p < 0.05), while expectation of disability improvement was associated 
      with GPC responder status (p < 0.05). At follow-up, comfort and expectation of 
      pain improvement were associated with responder GPC status (p < 0.05). No 
      association was found between responder pain, disability or GPC status and 
      biomechanical parameters of SMT at any time point. Discussion: No specific dosage 
      of SMT was associated with short-term clinical responses to treatment. However, 
      expectations of improvement and patient comfort during SMT were associated with a 
      positive response to treatment.
CI  - Copyright (c) 2022 Pasquier, Young, Lardon and Descarreaux.
FAU - Pasquier, Megane
AU  - Pasquier M
AD  - Department of Anatomy, Universite du Quebec a Trois-Rivieres, Trois-Rivieres, QC, 
      Canada.
AD  - Institut Franco-Europeen de Chiropraxie, Toulouse, France.
FAU - Young, James J
AU  - Young JJ
AD  - Center for Muscle and Joint Health Department, University of Southern Denmark, 
      Odense, Denmark.
AD  - Department of Research, Canadian Memorial Chiropractic College, Toronto, ON, 
      Canada.
FAU - Lardon, Arnaud
AU  - Lardon A
AD  - Institut Franco-Europeen de Chiropraxie, Toulouse, France.
AD  - Department of Human Kinetics, Universite du Quebec a Trois-Rivieres, 
      Trois-Rivieres, QC, Canada.
FAU - Descarreaux, Martin
AU  - Descarreaux M
AD  - Department of Human Kinetics, Universite du Quebec a Trois-Rivieres, 
      Trois-Rivieres, QC, Canada.
LA  - eng
PT  - Journal Article
DEP - 20220106
PL  - Switzerland
TA  - Front Pain Res (Lausanne)
JT  - Frontiers in pain research (Lausanne, Switzerland)
JID - 9918227269806676
PMC - PMC8915706
OTO - NOTNLM
OT  - association
OT  - comfort
OT  - manual therapies
OT  - observational study
OT  - prognosis
OT  - spine pain
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest. The reviewer PT declared a shared consortium with one of 
      the authors MD at time of review.
EDAT- 2022/03/18 06:00
MHDA- 2022/03/18 06:01
PMCR- 2022/01/06
CRDT- 2022/03/17 05:09
PHST- 2021/07/15 00:00 [received]
PHST- 2021/11/23 00:00 [accepted]
PHST- 2022/03/17 05:09 [entrez]
PHST- 2022/03/18 06:00 [pubmed]
PHST- 2022/03/18 06:01 [medline]
PHST- 2022/01/06 00:00 [pmc-release]
AID - 10.3389/fpain.2021.742119 [doi]
PST - epublish
SO  - Front Pain Res (Lausanne). 2022 Jan 6;2:742119. doi: 10.3389/fpain.2021.742119. 
      eCollection 2021.