PMID- 35295545
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220319
IS  - 2150-0878 (Print)
IS  - 2150-0886 (Electronic)
IS  - 2150-0878 (Linking)
VI  - 12
IP  - 8
DP  - 2021 Nov
TI  - Premedications for Cancer Therapies: A Primer for the Hematology/Oncology 
      Provider.
PG  - 810-832
LID - 10.6004/jadpro.2021.12.8.4 [doi]
AB  - Chemotherapeutic agents and radiation therapy are associated with numerous 
      potential adverse events (AEs). Many of these common AEs, namely chemotherapy- or 
      radiation-induced nausea and vomiting, hypersensitivity reactions, and edema, can 
      lead to deleterious outcomes (such as treatment nonadherence or cessation, or 
      poor clinical outcomes) if not prevented appropriately. The occurrence and 
      severity of these AEs can be prevented with the correct prescribing of 
      prophylactic medications, often called "premedications." The advanced 
      practitioner in hematology/oncology should have a good understanding of which 
      chemotherapeutic agents are known to place patients at risk for these adverse 
      events as well as be able to determine appropriate prophylactic medications to 
      employ in the prevention of these adverse events. While several guidelines and 
      literature exist regarding best practices for prophylaxis strategies, differences 
      among guidelines and quality of data should be explored in order to accurately 
      implement patient-specific recommendations. Herein, we review the existing 
      literature for prophylaxis and summarize best practices.
CI  - (c) 2021 Harborside.
FAU - Clemmons, Amber
AU  - Clemmons A
AD  - University of Georgia College of Pharmacy, Augusta, Georgia.
AD  - Augusta University Medical Center, Augusta, Georgia.
FAU - Gandhi, Arpita
AU  - Gandhi A
AD  - Emory Healthcare, Atlanta, Georgia.
FAU - Clarke, Andrea
AU  - Clarke A
AD  - Augusta University Medical Center, Augusta, Georgia.
FAU - Jimenez, Sarah
AU  - Jimenez S
AD  - Augusta University Medical Center, Augusta, Georgia.
FAU - Le, Thuy
AU  - Le T
AD  - Augusta University Medical Center, Augusta, Georgia.
FAU - Ajebo, Germame
AU  - Ajebo G
AD  - Augusta University Medical Center, Augusta, Georgia.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20211101
PL  - United States
TA  - J Adv Pract Oncol
JT  - Journal of the advanced practitioner in oncology
JID - 101550346
PMC - PMC8631343
COIS- Authors' disclosures of conflicts of interest are found at the end of this 
      article.
EDAT- 2022/03/18 06:00
MHDA- 2022/03/18 06:01
PMCR- 2021/11/01
CRDT- 2022/03/17 05:09
PHST- 2022/03/17 05:09 [entrez]
PHST- 2022/03/18 06:00 [pubmed]
PHST- 2022/03/18 06:01 [medline]
PHST- 2021/11/01 00:00 [pmc-release]
AID - 2021.12.8.4 [pii]
AID - 10.6004/jadpro.2021.12.8.4 [doi]
PST - ppublish
SO  - J Adv Pract Oncol. 2021 Nov;12(8):810-832. doi: 10.6004/jadpro.2021.12.8.4. Epub 
      2021 Nov 1.