PMID- 35295650
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220319
IS  - 2296-4185 (Print)
IS  - 2296-4185 (Electronic)
IS  - 2296-4185 (Linking)
VI  - 10
DP  - 2022
TI  - Enhanced Antimicrobial, Cytotoxicity, Larvicidal, and Repellence Activities of 
      Brown Algae, Cystoseira crinita-Mediated Green Synthesis of Magnesium Oxide 
      Nanoparticles.
PG  - 849921
LID - 10.3389/fbioe.2022.849921 [doi]
LID - 849921
AB  - Herein, the metabolites secreted by brown algae, Cystoseira crinita, were used as 
      biocatalyst for green synthesis of magnesium oxide nanoparticles (MgO-NPs). The 
      fabricated MgO-NPs were characterized using UV-vis spectroscopy, Fourier 
      transforms infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), 
      Scanning Electron Microscopy linked with energy-dispersive X-ray (SEM-EDX), X-ray 
      diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). Data showed 
      successful formation of crystallographic and spherical MgO-NPs with sizes of 
      3-18 nm at a maximum surface plasmon resonance of 320 nm. Moreover, EDX analysis 
      confirms the presence of Mg and O in the sample with weight percentages of 54.1% 
      and 20.6%, respectively. Phyco-fabricated MgO-NPs showed promising activities 
      against Gram-positive bacteria, Gram-negative bacteria, and Candida albicans with 
      MIC values ranging between 12.5 and 50 mug mL(-1). The IC(50) value of MgO-NPs 
      against cancer cell lines (Caco-2) was 113.4 mug mL(-1), whereas it was 141.2 mug 
      mL(-1) for normal cell lines (Vero cell). Interestingly, the green synthesized 
      MgO-NPs exhibited significant larvicidal and pupicidal activity against Musca 
      domestica. At 10 mug mL(-1) MgO-NPs, the highest mortality percentages were 99.0%, 
      95.0%, 92.2%, and 81.0% for I, II, III instars' larvae, and pupa of M. domestica, 
      respectively, with LC(50) values (3.08, 3.49, and 4.46 mug mL(-1)), and LC(90) 
      values (7.46, 8.89, and 10.43 mug mL(-1)), respectively. Also, MgO-NPs showed 
      repellence activity for adults of M. domestica at 10 mug mL(-1) with 63.0%, 77.9%, 
      84.9%, and 96.8% after 12, 24, 48, and 72 h, respectively.
CI  - Copyright (c) 2022 Fouda, Eid, Abdel-Rahman, EL-Belely, Awad, Hassan, AL-Faifi and 
      Hamza.
FAU - Fouda, Amr
AU  - Fouda A
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo, Egypt.
FAU - Eid, Ahmed M
AU  - Eid AM
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo, Egypt.
FAU - Abdel-Rahman, Mohamed Ali
AU  - Abdel-Rahman MA
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo, Egypt.
FAU - El-Belely, Ehab F
AU  - El-Belely EF
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo, Egypt.
FAU - Awad, Mohamed A
AU  - Awad MA
AD  - Department of Zoology and Entomology, Faculty of Science, Al-Azhar University, 
      Cairo, Egypt.
FAU - Hassan, Saad El-Din
AU  - Hassan SE
AD  - Botany and Microbiology Department, Faculty of Science, Al-Azhar University, 
      Cairo, Egypt.
FAU - Al-Faifi, Zarraq E
AU  - Al-Faifi ZE
AD  - Center for Environment Research and Studies, Jazan University, Jazan, Saudi 
      Arabia.
FAU - Hamza, Mohammed F
AU  - Hamza MF
AD  - School of Nuclear Science and Technology, University of South China, Heng Yang, 
      China.
AD  - Nuclear Materials Authority, Cairo, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20220228
PL  - Switzerland
TA  - Front Bioeng Biotechnol
JT  - Frontiers in bioengineering and biotechnology
JID - 101632513
PMC - PMC8920522
OTO - NOTNLM
OT  - Brown algae
OT  - Cystoseira crinita
OT  - MgO-NPs
OT  - antimicrobial
OT  - green synthesis
OT  - in-vitro cytotoxicity
OT  - larvicidal
OT  - repellence activity
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/03/18 06:00
MHDA- 2022/03/18 06:01
PMCR- 2022/01/01
CRDT- 2022/03/17 05:11
PHST- 2022/01/06 00:00 [received]
PHST- 2022/02/04 00:00 [accepted]
PHST- 2022/03/17 05:11 [entrez]
PHST- 2022/03/18 06:00 [pubmed]
PHST- 2022/03/18 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 849921 [pii]
AID - 10.3389/fbioe.2022.849921 [doi]
PST - epublish
SO  - Front Bioeng Biotechnol. 2022 Feb 28;10:849921. doi: 10.3389/fbioe.2022.849921. 
      eCollection 2022.