PMID- 35299739 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220319 IS - 2234-943X (Print) IS - 2234-943X (Electronic) IS - 2234-943X (Linking) VI - 12 DP - 2022 TI - Cystic Neoplasms of the Pancreas: Differential Diagnosis and Radiology Correlation. PG - 860740 LID - 10.3389/fonc.2022.860740 [doi] LID - 860740 AB - Although the probability of pancreatic cystic neoplasms (PCNs) being detected is raising year by year, their differential diagnosis and individualized treatment are still a challenge in clinical work. PCNs are tumors containing cystic components with different biological behaviors, and their clinical manifestations, epidemiology, imaging features, and malignant risks are different. Some are benign [e.g., serous cystic neoplasms (SCNs)], with a barely possible that turning into malignant, while others display a low or higher malignant risk [e.g., solid pseudopapillary neoplasms (SPNs), intraductal papillary mucinous neoplasms (IPMNs), and mucinous cystic neoplasms (MCNs)]. PCN management should concentrate on preventing the progression of malignant tumors while preventing complications caused by unnecessary surgical intervention. Clinically, various advanced imaging equipment are usually combined to obtain a more reliable preoperative diagnosis. The challenge for clinicians and radiologists is how to accurately diagnose PCNs before surgery so that corresponding surgical methods and follow-up strategies can be developed or not, as appropriate. The objective of this review is to sum up the clinical features, imaging findings and management of the most common PCNs according to the classic literature and latest guidelines. CI - Copyright (c) 2022 Hu, Hu, Wang, Ma, Yue, Tang, Liu, Wu, Peng and Tong. FAU - Hu, Feixiang AU - Hu F AD - Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. FAU - Hu, Yue AU - Hu Y AD - Hefei Cancer Hospital, Chinese Academy of Sciences (CAS), Hefei, China. FAU - Wang, Dan AU - Wang D AD - Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai, China. FAU - Ma, Xiaowen AU - Ma X AD - Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. FAU - Yue, Yali AU - Yue Y AD - Children's Hospital, Fudan University, Shanghai, China. FAU - Tang, Wei AU - Tang W AD - Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. FAU - Liu, Wei AU - Liu W AD - Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. FAU - Wu, Puye AU - Wu P AD - General Electric (GE) Healthcare, Shanghai, China. FAU - Peng, Weijun AU - Peng W AD - Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. FAU - Tong, Tong AU - Tong T AD - Department of Radiology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. LA - eng PT - Journal Article PT - Review DEP - 20220301 PL - Switzerland TA - Front Oncol JT - Frontiers in oncology JID - 101568867 PMC - PMC8921498 OTO - NOTNLM OT - intraductal papillary mucinous neoplasms (IPMNs) OT - mucinous cystic neoplasms (MCNs) OT - pancreatic cystic neoplasms (PCNs) OT - radiology OT - serous cystic neoplasms (SCN) OT - solid pseudopapillary neoplasms (SPN) COIS- Author PW was employed by GE Healthcare. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/03/19 06:00 MHDA- 2022/03/19 06:01 PMCR- 2022/01/01 CRDT- 2022/03/18 05:09 PHST- 2022/01/23 00:00 [received] PHST- 2022/02/04 00:00 [accepted] PHST- 2022/03/18 05:09 [entrez] PHST- 2022/03/19 06:00 [pubmed] PHST- 2022/03/19 06:01 [medline] PHST- 2022/01/01 00:00 [pmc-release] AID - 10.3389/fonc.2022.860740 [doi] PST - epublish SO - Front Oncol. 2022 Mar 1;12:860740. doi: 10.3389/fonc.2022.860740. eCollection 2022.