PMID- 35299797 OWN - NLM STAT- MEDLINE DCOM- 20220321 LR - 20220321 IS - 2075-0528 (Electronic) IS - 2075-051X (Print) IS - 2075-051X (Linking) VI - 22 IP - 1 DP - 2022 Feb TI - Serum Glucose Measurement after Five to Six Hours is Comparable to Eight Hours Fasting in Ramadan. PG - 123-128 LID - 10.18295/squmj.5.2021.084 [doi] AB - OBJECTIVES: This study aimed to evaluate whether a shorter fasting duration of five to six hours can be used as an alternative to the usually recommended eight hours for fasting glucose measurement. METHODS: This one-month observational, cross-sectional study was conducted during Ramadan (May to June) 2019. It included those attending Faiha Specialized Diabetes, Endocrine and Metabolism Center, Basrah, Iraq; all individuals ate a pre-dawn meal (suhoor) followed by a complete fast for many hours. Two fasting serum glucose (FSG) venous samples were taken; the first was taken five to six hours and the second eight hours after the pre-dawn meal. Participants were divided into two groups: individuals with type 2 diabetes mellitus (T2DM) and those with a normal glucose level. T2DM patients were further subdivided into three groups: those without treatment, those on oral antidiabetic drugs (OAD) and those using insulin and OAD. RESULTS: A total of 200 individuals participated in this study. There was no significant difference found between the mean FSG levels in the first and second samples for those without T2DM (104.5 +/- 21.4 mg/dL versus 104.8 +/- 12.6 mg/dL; P = 0.80) as well as those with T2DM (235.0 +/- 107.0 mg/dL versus 230.0 +/- 105.0 mg/dL; P = 0.20). Untreated T2DM patients had non-significant FSG readings for the two samples (194.0 +/- 151.5 mg/dL versus 193.9 +/- 128.9 mg/dL; P = 0.90). Patients on insulin and OAD showed a similar pattern of FSG (268.0 +/- 111.0 mg/dL versus 269.0 +/- 114.0 mg/dL). However, the two FSG samples were found to be significantly different among patients on OAD (220.0 +/- 78.0 mg/dL versus 207.0 +/- 77.0 mg/dL; P = 0.01). CONCLUSION: The fasting duration of five to six hours can give a comparable measurement of FSG as that obtained after eight hours. CI - (c) Copyright 2022, Sultan Qaboos University Medical Journal, All Rights Reserved. FAU - Almomin, Ammar M S AU - Almomin AMS AD - Faiha Specialized Diabetes, Endocrine and Metabolism Center, Basrah Health Directorate, Alzahraa College of Medicine, Basrah, Iraq. FAU - Odhaib, Samih A AU - Odhaib SA AD - College of Medicine, University of Basrah, Basrah, Iraq. FAU - Altemimi, Mahmood T AU - Altemimi MT AD - College of Medicine, University of Basrah, Basrah, Iraq. FAU - Nwayyir, Hussein A AU - Nwayyir HA AD - College of Medicine, University of Basrah, Basrah, Iraq. FAU - Hussein, Ibrahim H AU - Hussein IH AD - College of Medicine, University of Basrah, Basrah, Iraq. FAU - Alidrisi, Haider A Y AU - Alidrisi HAY AD - College of Medicine, University of Basrah, Basrah, Iraq. FAU - Alibrahim, Nassar T Y AU - Alibrahim NTY AD - College of Medicine, University of Basrah, Basrah, Iraq. FAU - Mansour, Abbas A AU - Mansour AA AD - College of Medicine, University of Basrah, Basrah, Iraq. LA - eng PT - Journal Article PT - Observational Study DEP - 20220228 PL - Oman TA - Sultan Qaboos Univ Med J JT - Sultan Qaboos University medical journal JID - 101519915 RN - 0 (Blood Glucose) SB - IM MH - Blood Glucose MH - Cross-Sectional Studies MH - *Diabetes Mellitus, Type 2/drug therapy MH - Fasting/metabolism MH - Humans MH - Islam PMC - PMC8904110 OTO - NOTNLM OT - Diabetes Mellitus OT - Duration of Therapy OT - Fasting OT - Glucose OT - Iraq COIS- CONFLICT OF INTEREST The authors declare no conflicts of interest. EDAT- 2022/03/19 06:00 MHDA- 2022/03/22 06:00 PMCR- 2022/02/01 CRDT- 2022/03/18 05:10 PHST- 2020/10/23 00:00 [received] PHST- 2021/01/06 00:00 [revised] PHST- 2021/01/30 00:00 [accepted] PHST- 2022/03/18 05:10 [entrez] PHST- 2022/03/19 06:00 [pubmed] PHST- 2022/03/22 06:00 [medline] PHST- 2022/02/01 00:00 [pmc-release] AID - squmj2202-123-128 [pii] AID - 10.18295/squmj.5.2021.084 [doi] PST - ppublish SO - Sultan Qaboos Univ Med J. 2022 Feb;22(1):123-128. doi: 10.18295/squmj.5.2021.084. Epub 2022 Feb 28.