PMID- 35319325 OWN - NLM STAT- MEDLINE DCOM- 20220620 LR - 20220620 IS - 1464-5246 (Electronic) IS - 0265-2048 (Linking) VI - 39 IP - 2 DP - 2022 Mar TI - Molecularly imprinted polymers: preparation, characterisation, and application in drug delivery systems. PG - 176-196 LID - 10.1080/02652048.2022.2055185 [doi] AB - Molecular imprinting technology defines the creation of molecularly imprinted polymer (MIP) molecules in which template molecules can place in a key-lock relationship through shape, diameter, and functional groups. Although molecular imprinting technology has been employed in different fields, its applications in drug delivery systems (DDSs) have gained momentum recently. The high loading efficiency, high stability, and controlled drug release are the primary advantages of MIPs. Here, the main components, preparation methods, and characterisation tests of MIPs are summarised, and their applications in DDSs administered by different routes are evaluated in detail. The review offers a perspective on molecular imprinting technology and applications of MIPs in drug delivery by surveying the literature approximately 1998-2021 together with the outlined prospects. FAU - Yuksel, Nilufer AU - Yuksel N AD - Department of Pharmaceutical Technology, Ankara University, Ankara, Turkey. FAU - Tektas, Sevgi AU - Tektas S AD - Department of Pharmaceutical Technology, Ankara University, Ankara, Turkey. LA - eng PT - Journal Article DEP - 20220324 PL - England TA - J Microencapsul JT - Journal of microencapsulation JID - 8500513 RN - 0 (Molecularly Imprinted Polymers) RN - 0 (Pharmaceutical Preparations) RN - 0 (Polymers) SB - IM MH - Drug Delivery Systems/methods MH - *Molecular Imprinting/methods MH - *Molecularly Imprinted Polymers MH - Pharmaceutical Preparations MH - Polymers OTO - NOTNLM OT - Molecular imprinting OT - controlled/sustained release OT - drug delivery OT - ophthalmic OT - oral OT - parenteral OT - polymerisation OT - template OT - transdermal EDAT- 2022/03/24 06:00 MHDA- 2022/06/22 06:00 CRDT- 2022/03/23 12:14 PHST- 2022/03/24 06:00 [pubmed] PHST- 2022/06/22 06:00 [medline] PHST- 2022/03/23 12:14 [entrez] AID - 10.1080/02652048.2022.2055185 [doi] PST - ppublish SO - J Microencapsul. 2022 Mar;39(2):176-196. doi: 10.1080/02652048.2022.2055185. Epub 2022 Mar 24.