PMID- 35324636
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220329
IS  - 2313-433X (Electronic)
IS  - 2313-433X (Linking)
VI  - 8
IP  - 3
DP  - 2022 Mar 19
TI  - A New Approach in Detectability of Microcalcifications in the Placenta during 
      Pregnancy Using Textural Features and K-Nearest Neighbors Algorithm.
LID - 10.3390/jimaging8030081 [doi]
LID - 81
AB  - (1) Background: Ultrasonography is the main method used during pregnancy to 
      assess the fetal growth, amniotic fluid, umbilical cord and placenta. The 
      placenta's structure suffers dynamic modifications throughout the whole pregnancy 
      and many of these changes, in which placental microcalcifications are by far the 
      most prominent, are related to the process of aging and maturation and have no 
      effect on fetal wellbeing. However, when placental microcalcifications are 
      noticed earlier during pregnancy, they could suggest a major placental 
      dysfunction with serious consequences for the fetus and mother. For better 
      detectability of microcalcifications, we propose a new approach based on 
      improving the clarity of details and the analysis of the placental structure 
      using first and second order statistics, and fractal dimension. (2) Methods: The 
      methodology is based on four stages: (i) cropping the region of interest and 
      preprocessing steps; (ii) feature extraction, first order-standard deviation 
      (SD), skewness (SK) and kurtosis (KR)-and second order-contrast (C), homogeneity 
      (H), correlation (CR), energy (E) and entropy (EN)-are computed from a gray level 
      co-occurrence matrix (GLCM) and fractal dimension (FD); (iii) statistical 
      analysis (t-test); (iv) classification with the K-Nearest Neighbors algorithm 
      (K-NN algorithm) and performance comparison with results from the support vector 
      machine algorithm (SVM algorithm). (3) Results: Experimental results obtained 
      from real clinical data show an improvement in the detectability and visibility 
      of placental microcalcifications.
FAU - Miron, Mihaela
AU  - Miron M
AD  - Department of Computer Science and Information Technology, Faculty of Automation, 
      Computers, Electrical Engineering and Electronics, Dunarea de Jos University of 
      Galati, 47 Domneasca Str., 800008 Galati, Romania.
FAU - Moldovanu, Simona
AU  - Moldovanu S
AUID- ORCID: 0000-0002-5934-329X
AD  - Department of Computer Science and Information Technology, Faculty of Automation, 
      Computers, Electrical Engineering and Electronics, Dunarea de Jos University of 
      Galati, 47 Domneasca Str., 800008 Galati, Romania.
FAU - Stefanescu, Bogdan Ioan
AU  - Stefanescu BI
AD  - Department of Clinical Surgical, Faculty of Medicine and Pharmacy, Dunarea de Jos 
      University of Galati, 47 Domneasca Str., 800008 Galati, Romania.
AD  - Department of Obstetrics and Gynecology, Clinical Emergency Hospital "Sf. Ap. 
      Andrei" Galati, 800578 Galati, Romania.
FAU - Culea, Mihai
AU  - Culea M
AD  - Department of Computer Science and Information Technology, Faculty of Automation, 
      Computers, Electrical Engineering and Electronics, Dunarea de Jos University of 
      Galati, 47 Domneasca Str., 800008 Galati, Romania.
FAU - Pavel, Sorin Marius
AU  - Pavel SM
AD  - Department of Electronics and Telecommunications, Faculty of Automation, 
      Computers, Electrical Engineering and Electronics, Dunarea de Jos University of 
      Galati, 47 Domneasca Str., 800008 Galati, Romania.
FAU - Culea-Florescu, Anisia Luiza
AU  - Culea-Florescu AL
AUID- ORCID: 0000-0002-1362-909X
AD  - Department of Electronics and Telecommunications, Faculty of Automation, 
      Computers, Electrical Engineering and Electronics, Dunarea de Jos University of 
      Galati, 47 Domneasca Str., 800008 Galati, Romania.
LA  - eng
PT  - Journal Article
DEP - 20220319
PL  - Switzerland
TA  - J Imaging
JT  - Journal of imaging
JID - 101698819
PMC - PMC8953054
OTO - NOTNLM
OT  - K-Nearest Neighbors algorithm
OT  - calcifications
OT  - first order feature
OT  - placenta
OT  - preterm placental calcifications
OT  - second order feature
OT  - support vector machine algorithm
OT  - t-test
COIS- The authors declare no conflict of interest.
EDAT- 2022/03/25 06:00
MHDA- 2022/03/25 06:01
PMCR- 2022/03/19
CRDT- 2022/03/24 17:24
PHST- 2021/12/20 00:00 [received]
PHST- 2022/03/14 00:00 [revised]
PHST- 2022/03/17 00:00 [accepted]
PHST- 2022/03/24 17:24 [entrez]
PHST- 2022/03/25 06:00 [pubmed]
PHST- 2022/03/25 06:01 [medline]
PHST- 2022/03/19 00:00 [pmc-release]
AID - jimaging8030081 [pii]
AID - jimaging-08-00081 [pii]
AID - 10.3390/jimaging8030081 [doi]
PST - epublish
SO  - J Imaging. 2022 Mar 19;8(3):81. doi: 10.3390/jimaging8030081.