PMID- 35334104 OWN - NLM STAT- MEDLINE DCOM- 20220609 LR - 20240504 IS - 2161-3311 (Electronic) IS - 2161-3311 (Linking) VI - 11 IP - 2 DP - 2022 Jun TI - Effect of Dietary Intake Through Whole Foods on Cognitive Function: Review of Randomized Controlled Trials. PG - 146-160 LID - 10.1007/s13668-022-00412-5 [doi] AB - PURPOSE OF REVIEW: This review evaluated recent randomized controlled trials (RCTs) examining the chronic intake of whole foods associated with the Mediterranean, Dietary Approaches to Stop Hypertension (DASH), Mediterranean-DASH Intervention for Neurogenerative Delay (MIND), and ketogenic (KETO) diets on cognitive function. RECENT FINDINGS: We identified RCTs related to olive oil (N = 3), nuts (N = 7), fatty fish (N = 1), lean meats (N = 4), fruits and vegetables (N = 9), legumes (N = 1), and low-fat dairy (N = 4), with 26/29 reporting positive results on at least one measure of cognition. We also identified 6 RCTs related to whole food-induced KETO diets, with half reporting positive effects on cognition. Variations in study design (i.e., generally the studies are < 6 months and include middle-aged and older, cognitively intact participants) and small sample sizes make it difficult to draw conclusions across studies; however, the current evidence from RCTs generally supports individual component intakes of these dietary patterns as an effective, nonpharmacological approach to improve cognitive health in adults. CI - (c) 2022. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply. FAU - Jiwani, Rozmin AU - Jiwani R AUID- ORCID: 0000-0002-2287-0758 AD - School of Nursing, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA. Jiwani@uthscsa.edu. AD - Geriatric Research, Education & Clinical Center (GRECC), South Texas Veterans Health Care System, San Antonio, TX, USA. Jiwani@uthscsa.edu. FAU - Robbins, Ronna AU - Robbins R AD - Geriatric Research, Education & Clinical Center (GRECC), South Texas Veterans Health Care System, San Antonio, TX, USA. FAU - Neri, Alfonso AU - Neri A AD - School of Nursing, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA. FAU - Renero, Jose AU - Renero J AD - Geriatric Research, Education & Clinical Center (GRECC), South Texas Veterans Health Care System, San Antonio, TX, USA. FAU - Lopez, Emme AU - Lopez E AD - Dolph Briscoe, Jr. Library, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. FAU - Serra, Monica C AU - Serra MC AD - Geriatric Research, Education & Clinical Center (GRECC), South Texas Veterans Health Care System, San Antonio, TX, USA. LA - eng GR - P30 AG044271/AG/NIA NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PT - Review DEP - 20220325 PL - United States TA - Curr Nutr Rep JT - Current nutrition reports JID - 101587480 SB - IM MH - Aged MH - Cognition MH - *Diet, Mediterranean MH - *Dietary Approaches To Stop Hypertension MH - Eating MH - Humans MH - Middle Aged MH - Randomized Controlled Trials as Topic MH - Vegetables OTO - NOTNLM OT - Cognitive function OT - DASH diet OT - Ketogenic diet OT - MIND diet OT - Mediterranean diet OT - Whole foods EDAT- 2022/03/26 06:00 MHDA- 2022/06/10 06:00 CRDT- 2022/03/25 17:26 PHST- 2022/03/10 00:00 [accepted] PHST- 2022/03/26 06:00 [pubmed] PHST- 2022/06/10 06:00 [medline] PHST- 2022/03/25 17:26 [entrez] AID - 10.1007/s13668-022-00412-5 [pii] AID - 10.1007/s13668-022-00412-5 [doi] PST - ppublish SO - Curr Nutr Rep. 2022 Jun;11(2):146-160. doi: 10.1007/s13668-022-00412-5. Epub 2022 Mar 25.