PMID- 35342133 OWN - NLM STAT- MEDLINE DCOM- 20220603 LR - 20231213 IS - 1349-7235 (Electronic) IS - 0918-2918 (Print) IS - 0918-2918 (Linking) VI - 61 IP - 11 DP - 2022 Jun 1 TI - Polymyalgia Rheumatica Following COVID-19 Vaccination. PG - 1775-1777 LID - 10.2169/internalmedicine.8934-21 [doi] AB - We herein report a 71-year-old woman presented with a fever, arthralgia, general malaise and leg muscle stiffness following administration of the COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). Laboratory findings showed an elevated C-reactive protein level and erythrocyte sedimentation rate. In addition, Gallium-67 scintigraphy demonstrated an increased uptake in multiple joints. Typing of human leukocyte antigen (HLA) revealed the presence of the DRB1*0404/*0803 allele. These findings met the diagnostic criteria for polymyalgia rheumatica (PMR), and when we started steroid treatment, her symptoms improved rapidly. This patient developed PMR after receiving a COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). This case is considered to be valuable, as the HLA-DRB1 allele was also confirmed. FAU - Yokote, Akira AU - Yokote A AD - Department of Neurology, Fukuoka University School of Medicine, Japan. FAU - Fujioka, Shinsuke AU - Fujioka S AD - Department of Neurology, Fukuoka University School of Medicine, Japan. FAU - Takahashi, Nobutaka AU - Takahashi N AD - Department of Neurology, Fukuoka University School of Medicine, Japan. FAU - Mishima, Takayasu AU - Mishima T AD - Department of Neurology, Fukuoka University School of Medicine, Japan. FAU - Tsuboi, Yoshio AU - Tsuboi Y AD - Department of Neurology, Fukuoka University School of Medicine, Japan. LA - eng PT - Case Reports PT - Journal Article DEP - 20220326 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (COVID-19 Vaccines) RN - 0 (Vaccines, Synthetic) RN - 0 (mRNA Vaccines) SB - IM MH - Aged MH - *COVID-19/prevention & control MH - *COVID-19 Vaccines/adverse effects MH - Female MH - Giant Cell Arteritis/diagnosis MH - Humans MH - *Polymyalgia Rheumatica/diagnosis/drug therapy MH - Vaccination MH - Vaccines, Synthetic MH - mRNA Vaccines PMC - PMC9259323 OTO - NOTNLM OT - COVID-19 OT - polymyalgia rheumatica OT - vaccination COIS- The authors state that they have no Conflict of Interest (COI). EDAT- 2022/03/29 06:00 MHDA- 2022/06/07 06:00 PMCR- 2022/06/01 CRDT- 2022/03/28 05:30 PHST- 2022/03/29 06:00 [pubmed] PHST- 2022/06/07 06:00 [medline] PHST- 2022/03/28 05:30 [entrez] PHST- 2022/06/01 00:00 [pmc-release] AID - 10.2169/internalmedicine.8934-21 [doi] PST - ppublish SO - Intern Med. 2022 Jun 1;61(11):1775-1777. doi: 10.2169/internalmedicine.8934-21. Epub 2022 Mar 26.