PMID- 35342461 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 1841-0987 (Print) IS - 1843-066X (Electronic) IS - 1841-0987 (Linking) VI - 17 IP - 3 DP - 2021 Jul-Sep TI - Correlation Between Serum 25(OH)D and Abdominal Visceral Fat Area in Patients with Type 2 Diabetes Mellitus in the Context of different Bone Mass. PG - 351-357 LID - 10.4183/aeb.2021.351 [doi] AB - OBJECTIVE: To investigate the correlation between serum levels of 25-hydroxy vitamin D [25(OH)D] and the visceral fat area of patients with type 2 diabetes mellitus (T2DM) in the context of different bone mass. MATERIALS AND METHODS: A total of 180 patients with T2DM were randomly selected for bone mineral density (BMD) examination. According to the results, they were divided into three groups: T2DM normal bone group (group A); T2DM bone mass reduction group (group B); T2DM osteoporosis group (group C). RESULT: Serum 25(OH)D levels in NC group, A group, B group and C group decreased in turn, and Visceral fat area (VFA) in group B and group C were significantly higher than those in group A and NC [(29.41+/-4.87) vs. (22.76+/-4.23) vs. (17.78+/-3.61) vs. (9.70+/-3.01), P<0.05], [(117.76+/-38.79), (125.08+/-37.90) vs. (89.79+/-26.51), (97.53+/-28.61), P<0.05]. Pearson correlation analysis showed that L1-L4 lumbar vertebrae bone density was positively correlated with 25(OH)D and VFA; left femoral neck bone density was positively correlated with 25(OH)D, and negatively correlated with VFA. CONCLUSION: Serum 25(OH)D and VFA may be associated with the development of T2DM combined with OP. CI - (c)2021 Acta Endocrinologica (Buc). FAU - Li, Q AU - Li Q AD - First Affiliated Hospital of Zunyi Medical College, Department of Endocrinology, Zunyi, China. FAU - Zhao, Y AU - Zhao Y AD - Department of Radiology, Zunyi, China. FAU - Wang, Y P AU - Wang YP AD - Department of Radiology, Zunyi, China. FAU - Yang, Y AU - Yang Y AD - First Affiliated Hospital of Zunyi Medical College, Department of Endocrinology, Zunyi, China. FAU - He, S M AU - He SM AD - First Affiliated Hospital of Zunyi Medical College, Department of Endocrinology, Zunyi, China. FAU - Zhang, X AU - Zhang X AD - First Affiliated Hospital of Zunyi Medical College, Department of Endocrinology, Zunyi, China. FAU - Wang, Z AU - Wang Z AD - First Affiliated Hospital of Zunyi Medical College, Department of Endocrinology, Zunyi, China. FAU - Luo, L Y AU - Luo LY AD - First Affiliated Hospital of Zunyi Medical College, Department of Endocrinology, Zunyi, China. LA - eng PT - Journal Article PL - Romania TA - Acta Endocrinol (Buchar) JT - Acta endocrinologica (Bucharest, Romania : 2005) JID - 101269720 PMC - PMC8919490 OTO - NOTNLM OT - 25-hydroxyvitamin D OT - abdominal visceral adipose area OT - bone density OT - type 2 diabetes mellitus EDAT- 2022/03/29 06:00 MHDA- 2022/03/29 06:01 PMCR- 2022/01/01 CRDT- 2022/03/28 05:30 PHST- 2022/03/28 05:30 [entrez] PHST- 2022/03/29 06:00 [pubmed] PHST- 2022/03/29 06:01 [medline] PHST- 2022/01/01 00:00 [pmc-release] AID - aeb.2021.351 [pii] AID - 10.4183/aeb.2021.351 [doi] PST - ppublish SO - Acta Endocrinol (Buchar). 2021 Jul-Sep;17(3):351-357. doi: 10.4183/aeb.2021.351.