PMID- 35343453 OWN - NLM STAT- MEDLINE DCOM- 20220331 LR - 20221207 IS - 1526-3711 (Electronic) IS - 1526-3711 (Linking) VI - 22 IP - 11 DP - 2021 Nov 1 TI - Effect of Two Nonsurgical Periodontal Treatment Modalities in Type 2 Diabetes Mellitus Patients with Chronic Periodontitis: A Randomized Clinical Trial. PG - 1275-1280 AB - AIM AND OBJECTIVE: The current study aimed to investigate the effect of two nonsurgical periodontal treatment modalities on clinical periodontal parameters and glycemic control. MATERIALS AND METHODS: A randomized clinical trial was conducted with a sample of 64 type 2 diabetes mellitus (T2DM) patients with chronic periodontitis. Subjects were randomly assigned into two groups. Group I received oral hygiene instructions (OHI) at baseline and each recall visit. Group II received one-stage full-mouth scaling and root planning (SRP) combining OHI. At baseline, third month, and sixth month the plaque index (PlI), gingival index (GI), probing pocket depth (PPD), clinical attachment loss (CAL), and glycated hemoglobin (HbA1c) were recorded and analyzed. RESULTS: After treatment, two groups showed signi fi cant differences for all parameters at both assessed times (p <0.05). The OHI alone only demonstrated a slight reduction in GI in third month, with no significant changes for PlI and PPD indexes. However, Group I recorded the increased HbA1c and CAL values at 6-month follow-up (p <0.05). The combination of OHI and SRP exhibited a significant improvement in all periodontal values (p <0.05). Also, the HbA1C levels of Group II showed a significant reduction after treatment and were lower than those of Group I. CONCLUSIONS: Oral hygiene instructions only resulted in a better gingival condition of diabetic patients in the initial time. The nonsurgical periodontal therapy by combining SRP and OHI significantly improved both periodontal health and glycemic control. CLINICAL SIGNIFICANCE: Diabetic patients should be supplied with an effective OHI modality and a professional dental debridement. FAU - Tran, Tan-Tai AU - Tran TT AD - Faculty of Odonto-stomatology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam. FAU - Ngo, Quynh-Trang Thi AU - Ngo QT AD - Faculty of Odonto-stomatology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam. FAU - Tran, Dang Huu AU - Tran DH AD - Faculty of Odonto-stomatology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam. FAU - Nguyen, Thuy-Duong Thi AU - Nguyen TT AD - Thuy-Duong Thi Nguyen, Faculty of Odonto-stomatology, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam, Phone: +0084 904181688, e-mail: nttduong@hueuni.edu.vn; nttduong@huemed-univ.edu.vn. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20211101 PL - India TA - J Contemp Dent Pract JT - The journal of contemporary dental practice JID - 101090552 RN - 0 (Glycated Hemoglobin A) SB - IM MH - *Chronic Periodontitis/complications/therapy MH - Dental Scaling/methods MH - *Diabetes Mellitus, Type 2/complications/therapy MH - Glycated Hemoglobin/analysis MH - Humans MH - Root Planing/methods OTO - NOTNLM OT - Chronic periodontitis OT - Glycemic control OT - Nonsurgical periodontal therapy Type 2 diabetes mellitus. EDAT- 2022/03/29 06:00 MHDA- 2022/04/01 06:00 CRDT- 2022/03/28 09:14 PHST- 2022/03/28 09:14 [entrez] PHST- 2022/03/29 06:00 [pubmed] PHST- 2022/04/01 06:00 [medline] AID - 1526-3711-2951 [pii] PST - epublish SO - J Contemp Dent Pract. 2021 Nov 1;22(11):1275-1280.