PMID- 35345058
OWN - NLM
STAT- MEDLINE
DCOM- 20220429
LR  - 20220429
IS  - 1479-8301 (Electronic)
IS  - 1346-3500 (Linking)
VI  - 22
IP  - 3
DP  - 2022 May
TI  - Behavioural and psychological symptoms of early-onset and late-onset Alzheimer's 
      disease among Chinese adults: analysis of modifiable factors.
PG  - 391-401
LID - 10.1111/psyg.12829 [doi]
AB  - BACKGROUND: To conduct a comprehensive comparison of behavioural and 
      psychological symptoms of dementia (BPSD) in Chinese people with early-onset 
      Alzheimer's disease (EOAD) and late-onset Alzheimer's disease (LOAD) and analyse 
      the factors of differences. METHODS: A cross-sectional survey of 93 EOAD and100 
      LOAD and their caregivers in China from November 2018 to May 2019. RESULTS: The 
      total Neuropsychiatric Inventory score was significantly higher in LOAD. A higher 
      level of agitation in EOAD was related to a lower quality of life of caregivers 
      and the emotional expression of ignoring people with dementia. Higher euphoria 
      scores in LOAD were associated with reduced negative coping by caregivers and 
      reduced stability and predictability at home. CONCLUSION: The early 
      identification and management of specific BPSD of EOAD and LOAD by family members 
      and health professionals may improve the quality of care and life for people with 
      dementia and that of caregivers.
CI  - (c) 2022 Japanese Psychogeriatric Society.
FAU - Fang, Shuyan
AU  - Fang S
AUID- ORCID: 0000-0003-3016-0454
AD  - School of Nursing, Jilin University, Changchun, China.
FAU - Zhang, Shuang
AU  - Zhang S
AUID- ORCID: 0000-0002-0857-8670
AD  - School of Nursing, Jilin University, Changchun, China.
FAU - Wang, Wenxia
AU  - Wang W
AD  - School of Nursing, Jilin University, Changchun, China.
FAU - Li, Yijing
AU  - Li Y
AD  - School of Nursing, Jilin University, Changchun, China.
FAU - Zhang, Xu
AU  - Zhang X
AD  - School of Nursing, Jilin University, Changchun, China.
FAU - Yu, Haisong
AU  - Yu H
AD  - School of Nursing, Jilin University, Changchun, China.
FAU - Sun, Jiao
AU  - Sun J
AD  - School of Nursing, Jilin University, Changchun, China.
LA  - eng
GR  - 2018090601/Ethics Committee of Jilin University/
PT  - Journal Article
DEP - 20220328
PL  - England
TA  - Psychogeriatrics
JT  - Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
JID - 101230058
SB  - IM
MH  - *Alzheimer Disease/diagnosis/psychology
MH  - Behavioral Symptoms/diagnosis/psychology
MH  - Caregivers/psychology
MH  - Cross-Sectional Studies
MH  - Humans
MH  - Quality of Life
OTO - NOTNLM
OT  - behavioural and psychological symptoms of dementia
OT  - early-onset Alzheimer's disease
OT  - late-onset Alzheimer's disease
OT  - modifiable factors
OT  - neuropsychiatric symptoms
EDAT- 2022/03/29 06:00
MHDA- 2022/04/30 06:00
CRDT- 2022/03/28 20:15
PHST- 2022/02/22 00:00 [revised]
PHST- 2021/11/04 00:00 [received]
PHST- 2022/03/14 00:00 [accepted]
PHST- 2022/03/29 06:00 [pubmed]
PHST- 2022/04/30 06:00 [medline]
PHST- 2022/03/28 20:15 [entrez]
AID - 10.1111/psyg.12829 [doi]
PST - ppublish
SO  - Psychogeriatrics. 2022 May;22(3):391-401. doi: 10.1111/psyg.12829. Epub 2022 Mar 
      28.