PMID- 35348614
OWN - NLM
STAT- MEDLINE
DCOM- 20230303
LR  - 20230328
IS  - 1460-2156 (Electronic)
IS  - 0006-8950 (Print)
IS  - 0006-8950 (Linking)
VI  - 146
IP  - 3
DP  - 2023 Mar 1
TI  - A genome-wide association study in autoimmune neurological syndromes with 
      anti-GAD65 autoantibodies.
PG  - 977-990
LID - 10.1093/brain/awac119 [doi]
AB  - Autoimmune neurological syndromes (AINS) with autoantibodies against the 65 kDa 
      isoform of the glutamic acid decarboxylase (GAD65) present with limbic 
      encephalitis, including temporal lobe seizures or epilepsy, cerebellitis with 
      ataxia, and stiff-person-syndrome or overlap forms. Anti-GAD65 autoantibodies are 
      also detected in autoimmune diabetes mellitus, which has a strong genetic 
      susceptibility conferred by human leukocyte antigen (HLA) and non-HLA genomic 
      regions. We investigated the genetic predisposition in patients with anti-GAD65 
      AINS. We performed a genome-wide association study (GWAS) and an association 
      analysis of the HLA region in a large German cohort of 1214 individuals. These 
      included 167 patients with anti-GAD65 AINS, recruited by the German Network for 
      Research on Autoimmune Encephalitis (GENERATE), and 1047 individuals without 
      neurological or endocrine disease as population-based controls. Predictions of 
      protein expression changes based on GWAS findings were further explored and 
      validated in the CSF proteome of a virtually independent cohort of 10 patients 
      with GAD65-AINS and 10 controls. Our GWAS identified 16 genome-wide significant 
      (P < 5 x 10-8) loci for the susceptibility to anti-GAD65 AINS. The top variant, 
      rs2535288 [P = 4.42 x 10-16, odds ratio (OR) = 0.26, 95% confidence interval (CI) 
      = 0.187-0.358], localized to an intergenic segment in the middle of the HLA class 
      I region. The great majority of variants in these loci (>90%) mapped to 
      non-coding regions of the genome. Over 40% of the variants have known regulatory 
      functions on the expression of 48 genes in disease relevant cells and tissues, 
      mainly CD4+ T cells and the cerebral cortex. The annotation of epigenomic marks 
      suggested specificity for neural and immune cells. A network analysis of the 
      implicated protein-coding genes highlighted the role of protein kinase C beta 
      (PRKCB) and identified an enrichment of numerous biological pathways 
      participating in immunity and neural function. Analysis of the classical HLA 
      alleles and haplotypes showed no genome-wide significant associations. The 
      strongest associations were found for the DQA1*03:01-DQB1*03:02-DRB1*04:01HLA 
      haplotype (P = 4.39 x 10-4, OR = 2.5, 95%CI = 1.499-4.157) and DRB1*04:01 allele 
      (P = 8.3 x 10-5, OR = 2.4, 95%CI = 1.548-3.682) identified in our cohort. As 
      predicted, the CSF proteome showed differential levels of five proteins (HLA-A/B, 
      C4A, ATG4D and NEO1) of expression quantitative trait loci genes from our GWAS in 
      the CSF proteome of anti-GAD65 AINS. These findings suggest a strong genetic 
      predisposition with direct functional implications for immunity and neural 
      function in anti-GAD65 AINS, mainly conferred by genomic regions outside the 
      classical HLA alleles.
CI  - (c) The Author(s) 2022. Published by Oxford University Press on behalf of the 
      Guarantors of Brain.
FAU - Strippel, Christine
AU  - Strippel C
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Herrera-Rivero, Marisol
AU  - Herrera-Rivero M
AD  - Department of Genetic Epidemiology, Institute of Human Genetics, University of 
      Munster, Munster, Germany.
FAU - Wendorff, Mareike
AU  - Wendorff M
AD  - Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 
      Kiel, Germany.
FAU - Tietz, Anja K
AU  - Tietz AK
AD  - Department of Neurology, University of Kiel, Kiel, Germany.
FAU - Degenhardt, Frauke
AU  - Degenhardt F
AUID- ORCID: 0000-0001-7516-3179
AD  - Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 
      Kiel, Germany.
FAU - Witten, Anika
AU  - Witten A
AD  - Department of Genetic Epidemiology, Institute of Human Genetics, University of 
      Munster, Munster, Germany.
FAU - Schroeter, Christina
AU  - Schroeter C
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Nelke, Christopher
AU  - Nelke C
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Golombeck, Kristin S
AU  - Golombeck KS
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Madlener, Marie
AU  - Madlener M
AD  - Department of Neurology, University of Cologne, Cologne, Germany.
FAU - Ruber, Theodor
AU  - Ruber T
AUID- ORCID: 0000-0002-6180-7671
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
AD  - Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University 
      Hospital Frankfurt, and LOEWE Center for Personalized Translational Epilepsy 
      Research (CePTER), Goethe-University Frankfurt, Frankfurt am Main, Germany.
FAU - Ernst, Leon
AU  - Ernst L
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Racz, Attila
AU  - Racz A
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Baumgartner, Tobias
AU  - Baumgartner T
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Widman, Guido
AU  - Widman G
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Doppler, Kathrin
AU  - Doppler K
AD  - Department of Neurology, University of Wurzburg, Wurzburg, Germany.
FAU - Thaler, Franziska
AU  - Thaler F
AUID- ORCID: 0000-0002-2138-2293
AD  - Institute of Clinical Neuroimmunology, University Hospital, 
      Ludwig-Maximilians-Universitat Munich, Munich, Germany.
AD  - Biomedical Center (BMC), Medical Faculty, Ludwig-Maximilians-Universitat Munich, 
      Martinsried, Germany.
FAU - Siebenbrodt, Kai
AU  - Siebenbrodt K
AD  - Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University 
      Hospital Frankfurt, and LOEWE Center for Personalized Translational Epilepsy 
      Research (CePTER), Goethe-University Frankfurt, Frankfurt am Main, Germany.
FAU - Dik, Andre
AU  - Dik A
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Kerin, Constanze
AU  - Kerin C
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Rauber, Saskia
AU  - Rauber S
AUID- ORCID: 0000-0001-8901-5572
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Gallus, Marco
AU  - Gallus M
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Kovac, Stjepana
AU  - Kovac S
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Grauer, Oliver M
AU  - Grauer OM
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Grimm, Alexander
AU  - Grimm A
AD  - Department of Neurology and Epileptology, Hertie Institute for Clinical Brain 
      Research, University of Tubingen, Tubingen, Germany.
FAU - Pruss, Harald
AU  - Pruss H
AD  - Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany.
FAU - Wickel, Jonathan
AU  - Wickel J
AD  - Section of Translational Neuroimmunology, Department of Neurology, Jena 
      University Hospital, Jena, Germany.
FAU - Geis, Christian
AU  - Geis C
AD  - Section of Translational Neuroimmunology, Department of Neurology, Jena 
      University Hospital, Jena, Germany.
FAU - Lewerenz, Jan
AU  - Lewerenz J
AD  - Department of Neurology, Ulm University, Ulm, Germany.
FAU - Goebels, Norbert
AU  - Goebels N
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Ringelstein, Marius
AU  - Ringelstein M
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
AD  - Center for Neurology and Neuropsychiatry, LVR Klinikum, Heinrich-Heine University 
      Dusseldorf, Dusseldorf, Germany.
FAU - Menge, Til
AU  - Menge T
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
AD  - Center for Neurology and Neuropsychiatry, LVR Klinikum, Heinrich-Heine University 
      Dusseldorf, Dusseldorf, Germany.
FAU - Tackenberg, Bjorn
AU  - Tackenberg B
AD  - Department of Neurology, University of Marburg/Giessen, Marburg, Germany.
FAU - Kellinghaus, Christoph
AU  - Kellinghaus C
AD  - Department of Neurology, Klinikum Osnabruck, Osnabruck, Germany.
FAU - Bien, Christian G
AU  - Bien CG
AUID- ORCID: 0000-0003-2225-8654
AD  - Department of Epileptology (Krankenhaus Mara), Bielefeld University, Medical 
      School, Campus Bielefeld-Bethel, Bielefeld, Germany.
FAU - Kraft, Andrea
AU  - Kraft A
AD  - Martha Maria Hospital Halle, Halle, Germany.
FAU - Zettl, Uwe
AU  - Zettl U
AD  - Department of Neurology, University of Rostock, Rostock, Germany.
FAU - Ismail, Fatme Seval
AU  - Ismail FS
AD  - Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr 
      University Bochum, Bochum, Germany.
FAU - Ayzenberg, Ilya
AU  - Ayzenberg I
AD  - Department of Neurology, I.M. Sechenov First Moscow State Medical University, 
      Moscow, Russia.
AD  - Department of Neurology, St Josefs Krankenhaus Bochum, Ruhr University Bochum, 
      Bochum, Germany.
FAU - Urbanek, Christian
AU  - Urbanek C
AD  - Department of Neurology, Ludwigshafen Hospital, Ludwigshafen, Germany.
FAU - Suhs, Kurt-Wolfram
AU  - Suhs KW
AD  - Department of Neurology, University Hospital, MHH, Hannover, Germany.
FAU - Tauber, Simone C
AU  - Tauber SC
AD  - Department of Neurology, University Hospital RWTH Aachen, Aachen, Germany.
FAU - Mues, Sigrid
AU  - Mues S
AD  - Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr 
      University Bochum, Bochum, Germany.
AD  - Department of Neurology, University Hospital Dresden, Dresden, Germany.
FAU - Kortvelyessy, Peter
AU  - Kortvelyessy P
AD  - Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany.
AD  - Department of Neurology, University Hospital Magdeburg, Magdeburg, Germany.
FAU - Markewitz, Robert
AU  - Markewitz R
AD  - Neuroimmunology, Institute of Clinical Chemistry, University Hospital 
      Schleswig-Holstein, Kiel/Lubeck, Germany.
FAU - Paliantonis, Asterios
AU  - Paliantonis A
AD  - Department of Neurology, Alfred-Krupp Hospital, Essen, Germany.
FAU - Elger, Christian E
AU  - Elger CE
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Surges, Rainer
AU  - Surges R
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Sommer, Claudia
AU  - Sommer C
AD  - Department of Neurology, University of Wurzburg, Wurzburg, Germany.
FAU - Kumpfel, Tania
AU  - Kumpfel T
AUID- ORCID: 0000-0001-7509-5268
AD  - Institute of Clinical Neuroimmunology, University Hospital, 
      Ludwig-Maximilians-Universitat Munich, Munich, Germany.
AD  - Biomedical Center (BMC), Medical Faculty, Ludwig-Maximilians-Universitat Munich, 
      Martinsried, Germany.
FAU - Gross, Catharina C
AU  - Gross CC
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Lerche, Holger
AU  - Lerche H
AD  - Department of Neurology and Epileptology, Hertie Institute for Clinical Brain 
      Research, University of Tubingen, Tubingen, Germany.
FAU - Wellmer, Jorg
AU  - Wellmer J
AD  - Department of Neurology, University Hospital Knappschaftskrankenhaus Bochum, Ruhr 
      University Bochum, Bochum, Germany.
FAU - Quesada, Carlos M
AU  - Quesada CM
AD  - Department of Neurology, University Hospital Essen, University of Duisburg-Essen, 
      Essen, Germany.
FAU - Then Bergh, Florian
AU  - Then Bergh F
AD  - Department of Neurology, University of Leipzig, Leipzig, Germany.
FAU - Wandinger, Klaus-Peter
AU  - Wandinger KP
AD  - Neuroimmunology, Institute of Clinical Chemistry, University Hospital 
      Schleswig-Holstein, Kiel/Lubeck, Germany.
FAU - Becker, Albert J
AU  - Becker AJ
AD  - Section of Translational Epileptology, Institute of Neuropathology, University of 
      Bonn, Bonn, Germany.
FAU - Kunz, Wolfram S
AU  - Kunz WS
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Meyer Zu Horste, Gerd
AU  - Meyer Zu Horste G
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Malter, Michael P
AU  - Malter MP
AD  - Department of Neurology, University of Cologne, Cologne, Germany.
FAU - Rosenow, Felix
AU  - Rosenow F
AD  - Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, University 
      Hospital Frankfurt, and LOEWE Center for Personalized Translational Epilepsy 
      Research (CePTER), Goethe-University Frankfurt, Frankfurt am Main, Germany.
FAU - Wiendl, Heinz
AU  - Wiendl H
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
FAU - Kuhlenbaumer, Gregor
AU  - Kuhlenbaumer G
AD  - Department of Neurology, University of Kiel, Kiel, Germany.
FAU - Leypoldt, Frank
AU  - Leypoldt F
AD  - Department of Neurology, University of Kiel, Kiel, Germany.
AD  - Neuroimmunology, Institute of Clinical Chemistry, University Hospital 
      Schleswig-Holstein, Kiel/Lubeck, Germany.
FAU - Lieb, Wolfgang
AU  - Lieb W
AD  - Institute of Epidemiology, Christian-Albrechts-University of Kiel, Kiel, Germany.
FAU - Franke, Andre
AU  - Franke A
AD  - Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 
      Kiel, Germany.
FAU - Meuth, Sven G
AU  - Meuth SG
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Stoll, Monika
AU  - Stoll M
AD  - Department of Genetic Epidemiology, Institute of Human Genetics, University of 
      Munster, Munster, Germany.
FAU - Melzer, Nico
AU  - Melzer N
AUID- ORCID: 0000-0002-2420-701X
AD  - Department of Neurology with Institute of Translational Neurology, University of 
      Munster, Munster, Germany.
AD  - Department of Neurology, Medical Faculty, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
CN  - German Network for Research on Autoimmune Encephalitis (GENERATE)
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Brain
JT  - Brain : a journal of neurology
JID - 0372537
RN  - 0 (Proteome)
RN  - 0 (Histocompatibility Antigens Class II)
RN  - 0 (HLA Antigens)
RN  - 0 (Autoantibodies)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Humans
MH  - *Genome-Wide Association Study
MH  - *Genetic Predisposition to Disease/genetics
MH  - Proteome/genetics
MH  - Histocompatibility Antigens Class II
MH  - HLA Antigens
MH  - Haplotypes
MH  - Alleles
MH  - Autoantibodies
MH  - HLA-DRB1 Chains/genetics
PMC - PMC9976967
OTO - NOTNLM
OT  - autoimmune encephalitis
OT  - genome-wide association study
OT  - glutamic acid decarboxylase
OT  - limbic encephalitis
OT  - stiff-person syndrome
FIR - Adelmann, Michael
IR  - Adelmann M
FIR - Appeltshauser, Luise
IR  - Appeltshauser L
FIR - Ayzenberg, Ilya
IR  - Ayzenberg I
FIR - Baade-Buttner, Carolin
IR  - Baade-Buttner C
FIR - van Baalen, Andreas
IR  - van Baalen A
FIR - Baatz, Sebastian
IR  - Baatz S
FIR - Balint, Bettina
IR  - Balint B
FIR - Bauer, Sebastian
IR  - Bauer S
FIR - Baumgartner, Annette
IR  - Baumgartner A
FIR - Benesch, Sonka
IR  - Benesch S
FIR - Berger, Robert
IR  - Berger R
FIR - Berning, Sascha
IR  - Berning S
FIR - Bernsen, Sarah
IR  - Bernsen S
FIR - Bien, Christian
IR  - Bien C
FIR - Bien, Corinna
IR  - Bien C
FIR - Binder, Andreas
IR  - Binder A
FIR - Bittner, Stefan
IR  - Bittner S
FIR - Bittner, Daniel
IR  - Bittner D
FIR - Blaes, Franz
IR  - Blaes F
FIR - Blaschek, Astrid
IR  - Blaschek A
FIR - Dargvainiene, Justina
IR  - Dargvainiene J
FIR - Decker, Julia
IR  - Decker J
FIR - Dik, Andre
IR  - Dik A
FIR - Doppler, Kathrin
IR  - Doppler K
FIR - Dreesmann, Mona
IR  - Dreesmann M
FIR - Ebinger, Friedrich
IR  - Ebinger F
FIR - Edelhoff, Lena
IR  - Edelhoff L
FIR - Ehrlich, Sven
IR  - Ehrlich S
FIR - Eisenhut, Katharina
IR  - Eisenhut K
FIR - Endres, Dominique
IR  - Endres D
FIR - Entscheva, Marina
IR  - Entscheva M
FIR - Hartmut Faiss, Jurgen
IR  - Hartmut Faiss J
FIR - Kristin Falk, Kim
IR  - Kristin Falk K
FIR - Fazeli, Walid
IR  - Fazeli W
FIR - Finke, Alexander
IR  - Finke A
FIR - Finke, Carsten
IR  - Finke C
FIR - Fitzner, Dirk
IR  - Fitzner D
FIR - Flotats-Bastardas, Marina
IR  - Flotats-Bastardas M
FIR - Fousse, Mathias
IR  - Fousse M
FIR - Friedemann, Paul
IR  - Friedemann P
FIR - Friese, Manuel
IR  - Friese M
FIR - Gallus, Marco
IR  - Gallus M
FIR - Gebhard, Marcel
IR  - Gebhard M
FIR - Geis, Christian
IR  - Geis C
FIR - Goedel, Clemens
IR  - Goedel C
FIR - Gorsler, Anna
IR  - Gorsler A
FIR - Grau, Armin
IR  - Grau A
FIR - Grauer, Oliver
IR  - Grauer O
FIR - Gross, Catharina
IR  - Gross C
FIR - Gul, Halime
IR  - Gul H
FIR - Ha-Yeun, Chung
IR  - Ha-Yeun C
FIR - Haghikia, Aiden
IR  - Haghikia A
FIR - Handreka, Robert
IR  - Handreka R
FIR - Hansen, Niels
IR  - Hansen N
FIR - Hausler, Martin
IR  - Hausler M
FIR - Havla, Joachim
IR  - Havla J
FIR - Heide, Wolfgang
IR  - Heide W
FIR - Held, Valentin
IR  - Held V
FIR - Hellwig, Kerstin
IR  - Hellwig K
FIR - Hillebrand, Philip
IR  - Hillebrand P
FIR - Hoffmann, Frank
IR  - Hoffmann F
FIR - Hoffmann, Anna
IR  - Hoffmann A
FIR - Hofstadt-van Oy, Ulrich
IR  - Hofstadt-van Oy U
FIR - Huppke, Peter
IR  - Huppke P
FIR - Seval Ismail, Fatme
IR  - Seval Ismail F
FIR - Jansen, Martina
IR  - Jansen M
FIR - Juranek, Aleksandra
IR  - Juranek A
FIR - Karenfort, Michael
IR  - Karenfort M
FIR - Kaufmann, Max
IR  - Kaufmann M
FIR - Kellinghaus, Christoph
IR  - Kellinghaus C
FIR - Kerin, Constanze
IR  - Kerin C
FIR - Knake, Susanne
IR  - Knake S
FIR - Kortvelyessy, Peter
IR  - Kortvelyessy P
FIR - Kovac, Stjepana
IR  - Kovac S
FIR - Kraft, Andrea
IR  - Kraft A
FIR - Kramer, Markus
IR  - Kramer M
FIR - Krogias, Christos
IR  - Krogias C
FIR - Kumpfel, Tanja
IR  - Kumpfel T
FIR - Lehrich, Christoph
IR  - Lehrich C
FIR - Lewerenz, Jan
IR  - Lewerenz J
FIR - Leypoldt, Frank
IR  - Leypoldt F
FIR - Linsa, Andeas
IR  - Linsa A
FIR - Lunemann, Jan
IR  - Lunemann J
FIR - Malter, Michael
IR  - Malter M
FIR - Meister, Monika
IR  - Meister M
FIR - Melzer, Nico
IR  - Melzer N
FIR - Stefanie Melzer, Kristin
IR  - Stefanie Melzer K
FIR - Menge, Til
IR  - Menge T
FIR - Meuth, Sven
IR  - Meuth S
FIR - Meyer Zu Horste, Gerd
IR  - Meyer Zu Horste G
FIR - Mono, Marie-Luise
IR  - Mono ML
FIR - Mues, Sigrid
IR  - Mues S
FIR - Nagel, Michael
IR  - Nagel M
FIR - Nelke, Christopher
IR  - Nelke C
FIR - Neumann-Haefelin, Tobias
IR  - Neumann-Haefelin T
FIR - Obrocki, Jost
IR  - Obrocki J
FIR - Penner, Loana
IR  - Penner L
FIR - Kristina Pfeffer, Lena
IR  - Kristina Pfeffer L
FIR - Pfefferkorn, Thomas
IR  - Pfefferkorn T
FIR - Philipsen, Alexandra
IR  - Philipsen A
FIR - Piepgras, Johannes
IR  - Piepgras J
FIR - von Poderwils, Felix
IR  - von Poderwils F
FIR - Priller, Josef
IR  - Priller J
FIR - Probstel, Anne-Katrin
IR  - Probstel AK
FIR - Pruss, Harald
IR  - Pruss H
FIR - Maria Helena Rau, Johanna
IR  - Maria Helena Rau J
FIR - Jania Rauber, Saskia
IR  - Jania Rauber S
FIR - Reimann, Gernot
IR  - Reimann G
FIR - Reinecke, Raphael
IR  - Reinecke R
FIR - Ringelstein, Marius
IR  - Ringelstein M
FIR - Rohner, Hendrik
IR  - Rohner H
FIR - Rosenow, Felix
IR  - Rosenow F
FIR - Rostasy, Kevin
IR  - Rostasy K
FIR - Ruber, Theodor
IR  - Ruber T
FIR - Ruegg, Stephan
IR  - Ruegg S
FIR - Schaumberg, Jens
IR  - Schaumberg J
FIR - Schilling, Ruth
IR  - Schilling R
FIR - Schimmel, Mareike
IR  - Schimmel M
FIR - Schmidt, Jens
IR  - Schmidt J
FIR - Schmutz, Ina-Isabelle
IR  - Schmutz II
FIR - Schreiber, Stephan
IR  - Schreiber S
FIR - Schreyer, Gesa
IR  - Schreyer G
FIR - Schroder, Ina
IR  - Schroder I
FIR - Schroter, Christina
IR  - Schroter C
FIR - Schuster, Simon
IR  - Schuster S
FIR - Seidel, Gunter
IR  - Seidel G
FIR - Senel, Makbule
IR  - Senel M
FIR - Siebenbrodt, Kai
IR  - Siebenbrodt K
FIR - Sommer, Claudia
IR  - Sommer C
FIR - Stammel, Oliver
IR  - Stammel O
FIR - Stangel, Martin
IR  - Stangel M
FIR - Stolze, Henning
IR  - Stolze H
FIR - Stoppe, Muriel
IR  - Stoppe M
FIR - Storm van S Gravesande, Karin
IR  - Storm van S Gravesande K
FIR - Strippel, Christine
IR  - Strippel C
FIR - Sturm, Dietrich
IR  - Sturm D
FIR - Suhs, Kurt-Wolfram
IR  - Suhs KW
FIR - Syrbe, Steffen
IR  - Syrbe S
FIR - Tauber, Simone
IR  - Tauber S
FIR - Teusser, Malte
IR  - Teusser M
FIR - Thaler, Franziska
IR  - Thaler F
FIR - Then Bergh, Florian
IR  - Then Bergh F
FIR - Trebst, Corinna
IR  - Trebst C
FIR - Trendelenburg, George
IR  - Trendelenburg G
FIR - Trollmann, Regina
IR  - Trollmann R
FIR - Tumani, Hayrettin
IR  - Tumani H
FIR - Turedi, Methab
IR  - Turedi M
FIR - Urbanek, Christian
IR  - Urbanek C
FIR - Vogel, Niklas
IR  - Vogel N
FIR - von Mering, Matthias
IR  - von Mering M
FIR - Wagner, Judith
IR  - Wagner J
FIR - Wandinger, Klaus-Peter
IR  - Wandinger KP
FIR - Weissert, Robert
IR  - Weissert R
FIR - Wickel, Jonathan
IR  - Wickel J
FIR - Wiendl, Heinz
IR  - Wiendl H
FIR - Wildemann, Brigitte
IR  - Wildemann B
FIR - Witt, Karsten
IR  - Witt K
FIR - Wunderlich, Benjamin
IR  - Wunderlich B
FIR - Zieger, Lara
IR  - Zieger L
EDAT- 2022/03/30 06:00
MHDA- 2023/03/04 06:00
PMCR- 2022/03/28
CRDT- 2022/03/29 12:19
PHST- 2021/10/17 00:00 [received]
PHST- 2022/02/11 00:00 [revised]
PHST- 2022/03/13 00:00 [accepted]
PHST- 2022/03/30 06:00 [pubmed]
PHST- 2023/03/04 06:00 [medline]
PHST- 2022/03/29 12:19 [entrez]
PHST- 2022/03/28 00:00 [pmc-release]
AID - 6555060 [pii]
AID - awac119 [pii]
AID - 10.1093/brain/awac119 [doi]
PST - ppublish
SO  - Brain. 2023 Mar 1;146(3):977-990. doi: 10.1093/brain/awac119.