PMID- 35350961 OWN - NLM STAT- MEDLINE DCOM- 20230502 LR - 20230510 IS - 1945-5119 (Electronic) IS - 1074-9357 (Linking) VI - 30 IP - 5 DP - 2023 Jul TI - Minimal and robust clinically important difference of three fatigue measures in chronic stroke survivors. PG - 522-531 LID - 10.1080/10749357.2022.2051830 [doi] AB - BACKGROUND: Fatigue assessment scale (FAS), fatigue subscale of the Profile of Mood States (POMS-F), and vitality subscale of the Short Form Health Survey (SF-36-VT) are among the first and most widely used adapted tools for assessing post-stroke fatigue. OBJECTIVE: To identify the minimal clinically important difference (MCID) and robust clinically important difference (RCID) of FAS, POMS-F, and SF-36-VT in stroke survivors. METHODS: Participants completed the FAS, POMS-F, and SF-36-VT before and after receiving 6-week intervention including graded activity training and pacing therapy. MCID was calculated using the distribution-based and anchor-based methods. Further, accuracy, sensitivity, and specificity of calculated values using the distribution-based method were used for determining RCID. RESULT: A total of 124 stroke survivors participated in this study. MCID for FAS, POMS-F, and SF-36-VT was found to be 4.86, 3.32, and -10.10 (using score change) and 3.5, 2.5, and -10.5 (using ROC analysis), respectively. Using the distribution-based method, the MCID value obtained for the FAS was in the range of 3.16 to 8.76, for the POMS-F was in the range of 1.49 to 5.63, and for the SF-36-VT was in the range of -15.43 to -5.58. (1/2)SD for FAS, (1/2) SD and 1.96 SEM for POMS-F, and 1.96 SEM and SD for SF-36-VT showed the best discriminative ability to use as the RCID. CONCLUSIONS: The MCID and RCID were calculated for FAS, POMS-F, and SF-36-VT using different methods. The results can be used by researchers and clinicians for interpreting their findings in subjects similar to those who participated in this study. FAU - Cheraghifard, Moslem AU - Cheraghifard M AD - PhD Student of Occupational Therapy, Rehabilitation Research Center, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran. FAU - Sarlak, Nazanin AU - Sarlak N AD - MSc of Occupational Therapy, Department of Occupational Therapy, School of Rehabilitation Sciences, Arak University of Medical Sciences, Arak, Iran. FAU - Taghizadeh, Ghorban AU - Taghizadeh G AUID- ORCID: 0000-0002-0145-9599 AD - PhD in Neurosciences. Rehabilitation Research Center, Department of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran. FAU - Azad, Akram AU - Azad A AUID- ORCID: 0000-0001-7544-4878 AD - PhD in Occupational Therapy, Associate Professor. Rehabilitation Research Center. Department of Occupational Therapy. School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran. FAU - Fallah, Soheila AU - Fallah S AD - PhD Student of Neurosciences, Department of Neurosciences, Faculty of Advanced Technologist in Medicine, Iran University of Medical Sciences, Tehran, Iran. FAU - Akbarfahimi, Malahat AU - Akbarfahimi M AUID- ORCID: 0000-0001-9966-3143 AD - PhD in Neurosciences, Associate Professor, Rehabilitation Research Center, Department of Occupational Therapy. School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220329 PL - England TA - Top Stroke Rehabil JT - Topics in stroke rehabilitation JID - 9439750 SB - IM MH - Humans MH - *Stroke/complications/therapy MH - Fatigue/diagnosis/etiology MH - Health Surveys MH - Brain Damage, Chronic MH - Survivors OTO - NOTNLM OT - Fatigue OT - health care OT - minimal clinically important difference OT - outcome assessment OT - rehabilitation OT - stroke EDAT- 2022/03/31 06:00 MHDA- 2023/05/02 06:42 CRDT- 2022/03/30 05:36 PHST- 2023/05/02 06:42 [medline] PHST- 2022/03/31 06:00 [pubmed] PHST- 2022/03/30 05:36 [entrez] AID - 10.1080/10749357.2022.2051830 [doi] PST - ppublish SO - Top Stroke Rehabil. 2023 Jul;30(5):522-531. doi: 10.1080/10749357.2022.2051830. Epub 2022 Mar 29.