PMID- 35351729
OWN - NLM
STAT- MEDLINE
DCOM- 20220421
LR  - 20220524
IS  - 2044-6055 (Electronic)
IS  - 2044-6055 (Linking)
VI  - 12
IP  - 3
DP  - 2022 Mar 29
TI  - Minimum clinically important difference of the Social Functioning in Dementia 
      Scale (SF-DEM): cross-sectional study and Delphi survey.
PG  - e058252
LID - 10.1136/bmjopen-2021-058252 [doi]
LID - e058252
AB  - OBJECTIVES: Good social functioning is important for people living with dementia 
      and their families. The Social Functioning in Dementia Scale (SF-DEM) is a valid 
      and reliable instrument measuring social functioning in dementia. However the 
      minimum clinically important difference (MCID) has not yet been derived for 
      SF-DEM. This study aims to define the MCID for the SF-DEM. DESIGN: We used 
      triangulation, incorporating data from a cross-sectional study to calculate the 
      MCID using distribution-based and anchor-based methods, and a Delphi survey. 
      SETTING AND PARTICIPANTS: The cross-sectional survey comprised 299 family carers 
      of people with dementia. Twenty dementia experts (researchers, clinicians, family 
      carers) rated whether changes on clinical vignettes represented a meaningful 
      change in the Delphi survey. PRIMARY OUTCOME MEASURES: We calculated the 
      distribution-based MCID as 0.5 of an SD for each of the three SF-DEM domains 
      (1-spending time with others, 2-communicating with others, 3-sensitivity to 
      others). We used the carers' rating of social functioning to calculate the 
      anchor-based MCID. For the Delphi survey, we defined consensus as >/=75% agreement. 
      Where there was lack of consensus, experts were asked to complete a further 
      survey round. RESULTS: We found that 0.5 SD of SF-DEM was 1.9 points, 2.2 and 1.4 
      points in domains 1, 2 and 3, respectively. Using the anchoring analysis, the 
      MCIDs were 1.7 points, 1.7 points, and 0.9 points in domains 1, 2 and 3, 
      respectively. The Delphi method required two rounds. In the second round, a 
      consensus was reached that a 2-point change was considered significant in all 
      three domains, but no consensus was reached on a 1-point change. CONCLUSIONS: By 
      triangulating all three methods, the SF-DEM's MCIDs were 1.9, 2.0 and 1.4 points 
      for domains 1, 2 and 3, respectively. For individuals, these values should be 
      rounded to a 2-point change for each domain.
CI  - (c) Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No 
      commercial re-use. See rights and permissions. Published by BMJ.
FAU - Levene, Tamara
AU  - Levene T
AD  - Division of Psychiatry, University College London, London, UK.
FAU - Livingston, Gill
AU  - Livingston G
AD  - Division of Psychiatry, University College London, London, UK.
AD  - Camden and Islington NHS Foundation Trust, London, UK.
FAU - Banerjee, Sube
AU  - Banerjee S
AD  - Faculty of Health, University of Plymouth, Plymouth, UK.
FAU - Sommerlad, Andrew
AU  - Sommerlad A
AUID- ORCID: 0000-0002-8895-7055
AD  - Division of Psychiatry, University College London, London, UK 
      a.sommerlad@ucl.ac.uk.
AD  - Camden and Islington NHS Foundation Trust, London, UK.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220329
PL  - England
TA  - BMJ Open
JT  - BMJ open
JID - 101552874
SB  - IM
MH  - Cross-Sectional Studies
MH  - *Dementia/diagnosis
MH  - Humans
MH  - Minimal Clinically Important Difference
MH  - *Social Interaction
MH  - Surveys and Questionnaires
PMC - PMC8966522
OTO - NOTNLM
OT  - delirium & cognitive disorders
OT  - dementia
OT  - epidemiology
OT  - old age psychiatry
COIS- Competing interests: None declared.
EDAT- 2022/03/31 06:00
MHDA- 2022/04/22 06:00
PMCR- 2022/03/29
CRDT- 2022/03/30 05:40
PHST- 2022/03/30 05:40 [entrez]
PHST- 2022/03/31 06:00 [pubmed]
PHST- 2022/04/22 06:00 [medline]
PHST- 2022/03/29 00:00 [pmc-release]
AID - bmjopen-2021-058252 [pii]
AID - 10.1136/bmjopen-2021-058252 [doi]
PST - epublish
SO  - BMJ Open. 2022 Mar 29;12(3):e058252. doi: 10.1136/bmjopen-2021-058252.