PMID- 35351730 OWN - NLM STAT- MEDLINE DCOM- 20220414 LR - 20221207 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 12 IP - 3 DP - 2022 Mar 28 TI - Nurse-led care versus usual care on cardiovascular risk factors for patients with type 2 diabetes: a systematic review and meta-analysis. PG - e058533 LID - 10.1136/bmjopen-2021-058533 [doi] LID - e058533 AB - OBJECTS: This study aims to systematically evaluate the effectiveness of nurse-led cares on cardiovascular risk factors among individuals with type 2 diabetes mellitus. DESIGN: Systematic review and meta-analysis. METHODS: The electronic databases PubMed, EMBASE, CINAHL and Cochrane Library databases were searched for randomised controlled trials of nurse-led care for individuals with type 2 diabetes mellitus (T2DM) published in English from inception to 23 December 2021. Random effects models were used to calculate weighted mean differences (WMD) with 95%CI. RESULTS: 13 articles were included in the meta-analysis, with a total of3757 participants. Considering baseline measurements, pooled analysis showed that nurse-led care significantly decreased the glycosylated haemoglobin (HbA1c) (WMD=-0.68 mmol/L; 95% CI -0.85 to -0.52; p<0.001), body mass index (BMI) (WMD=-0.54 kg/m(2); 95% CI: -0.97 to -0.11; p=0.01) and systolic blood pressure (SBP) (WMD=-1.17 mmHg; 95% CI: -2.11 to -0.22; p=0.02) for patients with T2DM. But there was no difference in low-density lipoprotein cholesterol (LDL-c) (WMD=-2.50 mg/dL ; 95% CI: -5.07 to 0.08; p=0.06) between the nurse-led and control groups. CONCLUSION: Nurse-led care is an effective and accessible intervention that could improve HbA1c, SBP, BMI levels among individuals with T2DM. PROSPERO REGISTRATION NUMBER: CRD42021248275. CI - (c) Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Zhang, Jiayu AU - Zhang J AUID- ORCID: 0000-0002-1151-992X AD - School of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, China. FAU - Zheng, Xutong AU - Zheng X AD - School of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, China. FAU - Ma, Danyan AU - Ma D AD - School of Medicine, Xiamen University, Xiamen, China. FAU - Liu, Changqin AU - Liu C AUID- ORCID: 0000-0001-8063-7906 AD - Department of Endocrinology and Diabetes, the First Affiliated Hospital of Xiamen University, School of medicine, Xiamen university, Xiamen, China liuchangqin@xmu.edu.cn xmdyyydyl@163.com. AD - The Third Clinical Medical College, Fujian Medical University, Fuzhou, China. AD - Xiamen Diabetes Quality Control Center, the First Affiliated Hospital of Xiamen University, School of medicine, Xiamen university, Xiamen, China. AD - Fujian Province Key Laboratory of Diabetes Translational Medicine, the First Affiliated Hospital of Xiamen University, School of medicine, Xiamen university, Xiamen, China. FAU - Ding, Yulan AU - Ding Y AD - Department of Nursing, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China liuchangqin@xmu.edu.cn xmdyyydyl@163.com. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Systematic Review DEP - 20220328 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 RN - 0 (Glycated Hemoglobin A) SB - IM MH - *Cardiovascular Diseases/etiology/prevention & control MH - *Diabetes Mellitus, Type 2/complications/therapy MH - Glycated Hemoglobin/analysis MH - Heart Disease Risk Factors MH - Humans MH - Nurse's Role MH - Risk Factors PMC - PMC8961115 OTO - NOTNLM OT - diabetes & endocrinology OT - education & training (see medical education & training) OT - risk management COIS- Competing interests: None declared. EDAT- 2022/03/31 06:00 MHDA- 2022/04/15 06:00 PMCR- 2022/03/28 CRDT- 2022/03/30 05:40 PHST- 2022/03/30 05:40 [entrez] PHST- 2022/03/31 06:00 [pubmed] PHST- 2022/04/15 06:00 [medline] PHST- 2022/03/28 00:00 [pmc-release] AID - bmjopen-2021-058533 [pii] AID - 10.1136/bmjopen-2021-058533 [doi] PST - epublish SO - BMJ Open. 2022 Mar 28;12(3):e058533. doi: 10.1136/bmjopen-2021-058533.