PMID- 35354545
OWN - NLM
STAT- MEDLINE
DCOM- 20220603
LR  - 20220603
IS  - 1879-1476 (Electronic)
IS  - 0385-8146 (Linking)
VI  - 49
IP  - 5
DP  - 2022 Oct
TI  - Ultrasonography for masses of the pharynx and larynx and assessment of laryngeal 
      squamous cell carcinoma.
PG  - 868-874
LID - S0385-8146(22)00065-7 [pii]
LID - 10.1016/j.anl.2022.03.002 [doi]
AB  - OBJECTIVE: To evaluate the ultrasonography (US) characteristics of 
      pharyngeal/laryngeal masses and the role of US in the assessment of laryngeal 
      squamous cell carcinoma (LSCC). METHODS: This study enrolled patients who 
      underwent US for evaluation of pharyngeal/laryngeal masses between 2018 and 2021. 
      Characteristics of pharyngeal/laryngeal masses and subsite invasion in cases of 
      LSCC were evaluated using US. RESULTS: Forty-six patients with pharyngeal 
      (n = 22) /laryngeal (n = 24) masses were enrolled. The pathological results were 
      benign and malignant in 7 (15.2%) and 39 (84.8%) patients, respectively. 
      Malignant masses were significantly associated with US characteristics of 
      heterogeneity (P = 0.002), irregular/speculated margin (P < 0.001), and increased 
      internal vascularity (P = 0.014) compared with benign masses. In patients with 
      LSCC, the detection rate of US for subsites invasion, including that of the 
      anterior commissure, paraglottic space, outer cortex of the thyroid cartilage, 
      cricoid cartilage, and extralaryngeal soft tissue, was similar to that of 
      computed tomography (CT). Although the difference was not statistically 
      significant, US more frequently demonstrated invasion of the inner cortex of the 
      thyroid cartilage than CT (40.9% vs. 22.7%; P = 0.195). US and CT had a 
      concordance rate of 81% (18 of 22 patients) in determining the tumour stage of 
      the lesions. CONCLUSION: US could facilitate differentiation between benign and 
      malignant masses of the pharynx and larynx in selective patients and has a 
      possible role in the assessment of LSCC.
CI  - Copyright (c) 2022. Published by Elsevier B.V.
FAU - Ahn, Dongbin
AU  - Ahn D
AD  - Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook 
      National University, Daegu, Korea. Electronic address: godlikeu@naver.com.
FAU - Kwak, Ji Hye
AU  - Kwak JH
AD  - Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook 
      National University, Daegu, Korea.
FAU - Lee, Gil Joon
AU  - Lee GJ
AD  - Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook 
      National University, Daegu, Korea.
FAU - Sohn, Jin Ho
AU  - Sohn JH
AD  - Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook 
      National University, Daegu, Korea.
LA  - eng
PT  - Journal Article
DEP - 20220327
PL  - Netherlands
TA  - Auris Nasus Larynx
JT  - Auris, nasus, larynx
JID - 7708170
SB  - IM
MH  - *Carcinoma, Squamous Cell/diagnostic imaging/pathology
MH  - *Head and Neck Neoplasms/pathology
MH  - Humans
MH  - *Laryngeal Neoplasms/diagnostic imaging/pathology
MH  - *Larynx/diagnostic imaging
MH  - Neoplasm Invasiveness/pathology
MH  - Neoplasm Staging
MH  - Pharynx/diagnostic imaging/pathology
MH  - Squamous Cell Carcinoma of Head and Neck/diagnostic imaging/pathology
MH  - Thyroid Cartilage/diagnostic imaging
MH  - Ultrasonography
OTO - NOTNLM
OT  - Laryngeal cancer
OT  - Larynx
OT  - Neoplasm staging
OT  - Pharynx
OT  - Ultrasonography
COIS- Conflict of interest None to declare.
EDAT- 2022/04/01 06:00
MHDA- 2022/06/07 06:00
CRDT- 2022/03/31 05:10
PHST- 2021/11/11 00:00 [received]
PHST- 2022/02/01 00:00 [revised]
PHST- 2022/03/04 00:00 [accepted]
PHST- 2022/04/01 06:00 [pubmed]
PHST- 2022/06/07 06:00 [medline]
PHST- 2022/03/31 05:10 [entrez]
AID - S0385-8146(22)00065-7 [pii]
AID - 10.1016/j.anl.2022.03.002 [doi]
PST - ppublish
SO  - Auris Nasus Larynx. 2022 Oct;49(5):868-874. doi: 10.1016/j.anl.2022.03.002. Epub 
      2022 Mar 27.