PMID- 35355377
OWN - NLM
STAT- MEDLINE
DCOM- 20220520
LR  - 20220520
IS  - 1365-2672 (Electronic)
IS  - 1364-5072 (Linking)
VI  - 132
IP  - 6
DP  - 2022 Jun
TI  - Antibacterial activity of palmarosa oil significantly varies between Aeromonas 
      veronii and Aeromonas caviae and exhibits selective action on tetracycline and 
      sulfonamide resistant A. caviae.
PG  - 4321-4329
LID - 10.1111/jam.15551 [doi]
AB  - AIMS: To investigate the antibacterial activity of three (palmarosa, basil and 
      rosemary) essential oils (EOs) on Aeromonas veronii and Aeromonas caviae, and 
      determine minimum inhibitory concentration (MIC) of potent EO against 
      tetracycline and sulfonamide resistant strains. METHODS AND RESULTS: Palmarosa 
      oil (PMO) showed significantly (p < 0.05) higher inhibition zones against both A. 
      veronii and A. caviae (n = 30) than basil and rosemary in the disk diffusion 
      assay. The MIC (% v/v) of PMO ranged from 0.008% to 1.00%. The mean MIC was 
      significantly higher for A. caviae (0.48 +/- 0.24%) than A. veronii (0.21 +/- 0.15%). 
      Further, the MIC of PMO was compared in six groups: Group 1: Tetracycline 
      Resistant A. veronii (TRV); Group 2: Tetracycline Resistant A. caviae (TRC); 
      Group 3: Sulfonamide Resistant A. veronii (SRV); Group 4: Sulfonamide Resistant 
      A. caviae (SRC); Group 5: Susceptible A. veronii (SV) and Group 6: Susceptible A. 
      caviae (SC). No significant differences were observed between overall resistant 
      (TRV+ SRV) and susceptible A. veronii (SV). However, in A. caviae, the resistant 
      group had a lower MIC than the susceptible group. Moreover, the MIC was 
      significantly lower for TRC (0.31 +/- 0.11%) as compared to SRC (0.46 +/- 0.10%). The 
      time of kill of PMO for both the species of Aeromonas was 20-30 min. CONCLUSION: 
      Palmarosa oil exhibited significantly higher activity on A. veronii than A. 
      caviae. The resistant strains of A. caviae were inhibited at a lower 
      concentration than susceptible strains. SIGNIFICANCE AND IMPACT OF THE STUDY: 
      Palmarosa oil could be explored as an alternative antimicrobial agent for 
      mitigating antimicrobial resistance and managing Aeromonas infection in fish and 
      their risks to public health.
CI  - (c) 2022 Society for Applied Microbiology.
FAU - Kumar, Chandra Bhushan
AU  - Kumar CB
AD  - ICAR-National Bureau of Fish Genetic Resources, Lucknow, India.
FAU - Kumar, Anil
AU  - Kumar A
AD  - ICAR-National Bureau of Fish Genetic Resources, Lucknow, India.
FAU - Rathore, Gaurav
AU  - Rathore G
AUID- ORCID: 0000-0003-0942-5518
AD  - ICAR-National Bureau of Fish Genetic Resources, Lucknow, India.
LA  - eng
PT  - Journal Article
DEP - 20220406
PL  - England
TA  - J Appl Microbiol
JT  - Journal of applied microbiology
JID - 9706280
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Sulfonamides)
RN  - F8VB5M810T (Tetracycline)
SB  - IM
MH  - *Aeromonas
MH  - *Aeromonas caviae
MH  - Aeromonas veronii
MH  - Animals
MH  - Anti-Bacterial Agents/pharmacology
MH  - *Gram-Negative Bacterial Infections/drug therapy/microbiology
MH  - Microbial Sensitivity Tests
MH  - Sulfonamides
MH  - Tetracycline/pharmacology
EDAT- 2022/04/01 06:00
MHDA- 2022/05/21 06:00
CRDT- 2022/03/31 05:15
PHST- 2022/03/03 00:00 [revised]
PHST- 2022/01/26 00:00 [received]
PHST- 2022/03/21 00:00 [accepted]
PHST- 2022/04/01 06:00 [pubmed]
PHST- 2022/05/21 06:00 [medline]
PHST- 2022/03/31 05:15 [entrez]
AID - 10.1111/jam.15551 [doi]
PST - ppublish
SO  - J Appl Microbiol. 2022 Jun;132(6):4321-4329. doi: 10.1111/jam.15551. Epub 2022 
      Apr 6.