PMID- 35356479 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220401 IS - 1831-4732 (Electronic) IS - 1831-4732 (Linking) VI - 20 IP - 3 DP - 2022 Mar TI - Modification of the existing maximum residue level for apricots and setting of import tolerances for cyantraniliprole in various crops. PG - e07219 LID - 10.2903/j.efsa.2022.7219 [doi] LID - e07219 AB - In accordance with Article 6 of Regulation (EC) No 396/2005, the applicants FMC International and Syngenta Crop Protection submitted two requests to the competent national authority in France, respectively, to set import tolerances for the active substance cyantraniliprole in various crops and to modify the existing maximum residue levels (MRLs) in apricots. The data submitted in support of the requests were found sufficient to derive MRL proposals for apricots, potatoes, tropical root and tuber vegetables, cucurbits (inedible peel), lettuces and salad plants, Chinese cabbage and other leafy brassica (except kale), spinaches and similar leaves (except spinach), parsley and minor oilseeds. Based on the risk assessment results, EFSA concluded that the dietary intake of residues resulting from the uses of cyantraniliprole according to the reported agricultural practices is unlikely to present a risk to consumer health for the parent compound. A definitive conclusion on the risk for consumers cannot be derived for the degradation products IN-N5M09 and IN-F6L99 which are formed during cooking/boiling. For both compounds, the concerns on genotoxicity have been ruled out, but the general toxicity has not been addressed. The indicative exposure calculated by the EMS and EFSA for these compounds is affected by non-standard uncertainties but can support risk managers to take an informed decision on the requested modification of the existing MRLs for the crops under assessment. CI - (c) 2022 Wiley-VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority. CN - European Food Safety Authority (EFSA) FAU - Bellisai, Giulia AU - Bellisai G FAU - Bernasconi, Giovanni AU - Bernasconi G FAU - Brancato, Alba AU - Brancato A FAU - Carrasco Cabrera, Luis AU - Carrasco Cabrera L FAU - Castellan, Irene AU - Castellan I FAU - Ferreira, Lucien AU - Ferreira L FAU - Giner, German AU - Giner G FAU - Greco, Luna AU - Greco L FAU - Jarrah, Samira AU - Jarrah S FAU - Leuschner, Renata AU - Leuschner R FAU - Magrans, Jose Oriol AU - Magrans JO FAU - Miron, Ileana AU - Miron I FAU - Nave, Stefanie AU - Nave S FAU - Pedersen, Ragnor AU - Pedersen R FAU - Reich, Hermine AU - Reich H FAU - Ruocco, Silvia AU - Ruocco S FAU - Santos, Miguel AU - Santos M FAU - Scarlato, Alessia Pia AU - Scarlato AP FAU - Theobald, Anne AU - Theobald A FAU - Verani, Alessia AU - Verani A LA - eng PT - Journal Article DEP - 20220328 PL - United States TA - EFSA J JT - EFSA journal. European Food Safety Authority JID - 101642076 PMC - PMC8958500 OTO - NOTNLM OT - MRL OT - consumer risk assessment OT - cyantraniliprole OT - import tolerance OT - pesticide OT - various crops EDAT- 2022/04/01 06:00 MHDA- 2022/04/01 06:01 PMCR- 2022/03/28 CRDT- 2022/03/31 05:32 PHST- 2022/03/31 05:32 [entrez] PHST- 2022/04/01 06:00 [pubmed] PHST- 2022/04/01 06:01 [medline] PHST- 2022/03/28 00:00 [pmc-release] AID - EFS27219 [pii] AID - 10.2903/j.efsa.2022.7219 [doi] PST - epublish SO - EFSA J. 2022 Mar 28;20(3):e07219. doi: 10.2903/j.efsa.2022.7219. eCollection 2022 Mar.