PMID- 35361431
OWN - NLM
STAT- MEDLINE
DCOM- 20220404
LR  - 20220405
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 1203
DP  - 2022 Apr 22
TI  - A novel magnetic molecularly imprinted polymer for selective extraction and 
      determination of quercetin in plant samples.
PG  - 339709
LID - S0003-2670(22)00280-X [pii]
LID - 10.1016/j.aca.2022.339709 [doi]
AB  - Molecularly imprinted polymers that mimic the binding mechanism of antibodies and 
      their antigens exhibit several advantages, such as fast synthesis, low cost, high 
      stability, and allow to overcome the ethical issues associated with antibody 
      farming in animals. Herein, a novel strategy combining the magnetic molecularly 
      imprinted polymer (MMIP) as an artificial antibody with a fluorescence procedure 
      for the detection of quercetin in plant samples was designed. The MMIP was 
      synthesized via a radical polymerization process to recognize specific functional 
      groups of quercetin using a green technique based on high energy ultrasound 
      irradiation. The developed MMIP was characterized by Fourier transform infrared 
      spectroscopy, X-ray diffraction, scanning/transmission electron microscopy, and 
      thermal gravimetric analysis, which confirmed the successful preparation of MMIP. 
      The adsorption capacity and selectivity of the MMIP for quercetin and other 
      interferents analogous were performed. The MMIP was applied in the solid-phase 
      extraction (SPE) technique as a selective sorbent for the sample preparation. 
      Besides, a sensitive fluorometric method for the quantitation of quercetin was 
      developed. A linear response was obtained within the concentration of 
      0.005-1.25 mug mL(-1) of quercetin. The limit of detection and quantitation were 
      1.1 ng mL(-1) and 3.7 ng mL(-1), respectively. The average recoveries for 
      quercetin were between 92.2% and 104.7% with an RSD less than 5.06% in spiked 
      orange juice and tea extract samples. Furthermore, the developed procedure was 
      successfully combined with a new paper-based analytical device for on-site 
      smartphone analysis of quercetin.
CI  - Copyright (c) 2022 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Karrat, Abdelhafid
AU  - Karrat A
AD  - Laboratory of Process Engineering and Environment, Faculty of Sciences and 
      Techniques, Hassan II University of Casablanca, P.A. 146, Mohammedia, Morocco; 
      Department of Analytical Chemistry, Institute of Research on Electron Microscopy 
      and Materials (IMEYMAT), Faculty of Sciences, Campus de Excelencia Internacional 
      del Mar (CEIMAR), University of Cadiz, Campus Universitario de Puerto Real, 
      Poligono del Rio San Pedro S/N, 11510, Puerto Real, Cadiz, Spain.
FAU - Palacios-Santander, Jose Maria
AU  - Palacios-Santander JM
AD  - Department of Analytical Chemistry, Institute of Research on Electron Microscopy 
      and Materials (IMEYMAT), Faculty of Sciences, Campus de Excelencia Internacional 
      del Mar (CEIMAR), University of Cadiz, Campus Universitario de Puerto Real, 
      Poligono del Rio San Pedro S/N, 11510, Puerto Real, Cadiz, Spain. Electronic 
      address: josem.palacios@uca.es.
FAU - Amine, Aziz
AU  - Amine A
AD  - Laboratory of Process Engineering and Environment, Faculty of Sciences and 
      Techniques, Hassan II University of Casablanca, P.A. 146, Mohammedia, Morocco. 
      Electronic address: azizamine@yahoo.fr.
FAU - Cubillana-Aguilera, Laura
AU  - Cubillana-Aguilera L
AD  - Department of Analytical Chemistry, Institute of Research on Electron Microscopy 
      and Materials (IMEYMAT), Faculty of Sciences, Campus de Excelencia Internacional 
      del Mar (CEIMAR), University of Cadiz, Campus Universitario de Puerto Real, 
      Poligono del Rio San Pedro S/N, 11510, Puerto Real, Cadiz, Spain.
LA  - eng
PT  - Journal Article
DEP - 20220310
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Molecularly Imprinted Polymers)
RN  - 9IKM0I5T1E (Quercetin)
SB  - IM
MH  - Animals
MH  - Magnetic Phenomena
MH  - Magnetics
MH  - *Molecular Imprinting/methods
MH  - Molecularly Imprinted Polymers
MH  - Quercetin
OTO - NOTNLM
OT  - Fluorescence detection
OT  - High energy ultrasound-based synthesis
OT  - Magnetic nanoparticles
OT  - Molecularly imprinted polymers
OT  - Paper-based analytical device
OT  - Quercetin
OT  - Solid-phase extraction
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/04/02 06:00
MHDA- 2022/04/05 06:00
CRDT- 2022/04/01 05:32
PHST- 2022/01/21 00:00 [received]
PHST- 2022/03/07 00:00 [revised]
PHST- 2022/03/08 00:00 [accepted]
PHST- 2022/04/01 05:32 [entrez]
PHST- 2022/04/02 06:00 [pubmed]
PHST- 2022/04/05 06:00 [medline]
AID - S0003-2670(22)00280-X [pii]
AID - 10.1016/j.aca.2022.339709 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2022 Apr 22;1203:339709. doi: 10.1016/j.aca.2022.339709. Epub 
      2022 Mar 10.