PMID- 35362702 OWN - NLM STAT- MEDLINE DCOM- 20220405 LR - 20220405 IS - 0039-1735 (Print) IS - 0039-1735 (Linking) VI - 101 IP - 2 DP - 2022 TI - [Clinical efficacy of hydroxyapatite and tricalcium phosphate modified with hyaluronic acid in the treatment of patients with periimplantitis]. PG - 42-46 LID - 10.17116/stomat202210102142 [doi] AB - THE AIM OF THE STUDY: Was to assess the effectiveness of the use of hydroxyapatite (HAP) and tricalcium phosphate (TCF) modified with hyaluronic acid in the treatment of patients with periimplantitis. MATERIALS AND METHODS: Clinical studies were conducted in 128 patients (44% male and 56% female) aged up to 55 years, who sought dental care with the main diagnosis of periimplant mucositis and periimplantitis. To compare the features of osseointegration of dental implants under bone remodeling three groups of patients were formed: one control and 2 main ones. In the control group the wound was managed under a blood clot, in the first main group HAP and TCF and in the second main group HAP and TCF modified with hyaluronic acid were used. X-ray examination was performed in various modes. Clinical assessment of implant stability in the operated area was carried out using subjective (percussion and palpation method) and objective method of frequency resonance analysis using the Osstell ISQ device calculating the stability coefficient of the dental implant (SCDI). RESULTS: 12 months after the periimplant zone remodeling procedure the bone resorption rates surrounding the implant were statistically significantly the lowest in the second main group (0.682+/-0.006 mm, p<0.001) compared with the values in the control and first main groups (1.626+/-0.022 and 1.025+/-0.034 mm, respectively). In the former groups bone resorption continued to progress during the observation period. In patients of the second main group, the average values of the SCDI for all study periods were 68.97+/-1.09 units which turned out to be the highest indicator and significantly differed from the values of other observation groups (p<0.05), which may be due to a tighter fit of the implants to the surface of the newly formed bone tissue. CONCLUSION: The results of the study 12 months after the periimplant zone remodeling operation procedure prove the efficacy of HAP and TCF modified with hyaluronic acid for the treatment of patients with periimplantitis. FAU - Garunov, M M AU - Garunov MM AUID- ORCID: 0000-0003-0563-0741 AD - Peoples' Friendship University of Russia, Moscow, Russia. FAU - Grigoriyants, L A AU - Grigoriyants LA AUID- ORCID: 0000-0003-3226-3641 AD - Peoples' Friendship University of Russia, Moscow, Russia. FAU - Stepanov, A G AU - Stepanov AG AUID- ORCID: 0000-0002-6543-0998 AD - Peoples' Friendship University of Russia, Moscow, Russia. FAU - Apresyan, S V AU - Apresyan SV AUID- ORCID: 0000-0002-3281-707X AD - Peoples' Friendship University of Russia, Moscow, Russia. FAU - Simonyan, D V AU - Simonyan DV AUID- ORCID: 0000-0001-8826-7428 AD - Peoples' Friendship University of Russia, Moscow, Russia. LA - rus PT - Journal Article TT - Klinicheskaya effektivnost' primeneniya gidroksiapatita i trikal'tsiifosfata, modifitsirovannykh gialuronovoi kislotoi v lechenii patsientov s periimplantitami. PL - Russia (Federation) TA - Stomatologiia (Mosk) JT - Stomatologiia JID - 0412072 RN - 0 (Calcium Phosphates) RN - 0 (Dental Implants) RN - 9004-61-9 (Hyaluronic Acid) RN - 91D9GV0Z28 (Durapatite) RN - K4C08XP666 (tricalcium phosphate) SB - IM MH - Aged MH - Calcium Phosphates MH - *Dental Implants/adverse effects MH - Durapatite/therapeutic use MH - Female MH - Humans MH - Hyaluronic Acid/therapeutic use MH - Male MH - *Peri-Implantitis/diagnostic imaging/drug therapy MH - Treatment Outcome OTO - NOTNLM OT - hyaluronic acid OT - hydroxyapatite OT - periimplant mucositis OT - periimplantitis OT - tricalcium phosphate EDAT- 2022/04/02 06:00 MHDA- 2022/04/06 06:00 CRDT- 2022/04/01 10:42 PHST- 2022/04/01 10:42 [entrez] PHST- 2022/04/02 06:00 [pubmed] PHST- 2022/04/06 06:00 [medline] AID - 10.17116/stomat202210102142 [doi] PST - ppublish SO - Stomatologiia (Mosk). 2022;101(2):42-46. doi: 10.17116/stomat202210102142.