PMID- 35362916
OWN - NLM
STAT- MEDLINE
DCOM- 20220509
LR  - 20220803
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 32
IP  - 6
DP  - 2022 Jun
TI  - Long-term Impact of Laparoscopic Sleeve Gastrectomy on Drug Costs of Japanese 
      Patients with Obesity and Type 2 Diabetes Mellitus.
PG  - 1831-1841
LID - 10.1007/s11695-022-06036-6 [doi]
AB  - PURPOSE: Laparoscopic sleeve gastrectomy (LSG) is the most common type of 
      bariatric surgery in Japan, and it is the only such procedure covered by national 
      health insurance. The long-term cost of bariatric surgery in Japan has not yet 
      been analyzed. We aimed to evaluate the long-term impact of LSG on the drug 
      treatment costs of patients with type 2 diabetes mellitus (T2DM). MATERIALS AND 
      METHODS: We retrospectively analyzed data from 230 patients who had undergone LSG 
      at our institution for their obesity and T2DM between 2007 and 2018. The 
      clinicopathological data included age, sex, body mass index (BMI), as well as 
      preoperative and postoperative medications for T2DM, hypertension, and 
      dyslipidemia. We then calculated the drug treatment costs for T2DM, hypertension, 
      and dyslipidemia before and after LSG; and we evaluated the remission rates of 
      these obesity-related diseases. RESULTS: The median preoperative body weight and 
      BMI of the 230 patients who underwent LSG were 115 kg and 40.6 kg/m(2), 
      respectively. Preoperative drug treatment costs per month per patient for T2DM, 
      hypertension, and dyslipidemia were  yen3795 ( yen0-40285),  yen3269 ( yen0-14577), and  yen1428 
      ( yen0-19464). Post-operation, the median drug treatment costs for all these 
      diseases became nil. The remission rates of T2DM, hypertension, and dyslipidemia 
      5 years after LSG were 82.8%, 50%, and 43.8%, respectively. In Japan, the cost of 
      an LSG operation corresponds to 4.75 years of median drug costs to treat T2DM and 
      hypertension. CONCLUSION: In the long term, LSG in Japan is effective both 
      physically and cost-wise for patients with obesity and T2DM.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Otake, Reiko
AU  - Otake R
AD  - Weight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, 
      Chiyoda-ku, Tokyo, 102-0084, Japan.
AD  - Department of Surgery, Shiga University of Medical Science, Setatsukinowa-cho, 
      Otsu, Shiga, 520-2192, Japan.
FAU - Seki, Yosuke
AU  - Seki Y
AUID- ORCID: 0000-0003-0965-7415
AD  - Weight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, 
      Chiyoda-ku, Tokyo, 102-0084, Japan. y-seki@mcube.jp.
FAU - Kasama, Kazunori
AU  - Kasama K
AD  - Weight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, 
      Chiyoda-ku, Tokyo, 102-0084, Japan.
FAU - Yokoyama, Renzo
AU  - Yokoyama R
AD  - Weight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, 7-7 Nibancho, 
      Chiyoda-ku, Tokyo, 102-0084, Japan.
FAU - Kurokawa, Yoshimochi
AU  - Kurokawa Y
AD  - Department of Surgery, Yotsuya Medical Cube, 7-7 Nibancho, Chiyoda-ku, Tokyo, 
      102-0084, Japan.
FAU - Tani, Masaji
AU  - Tani M
AD  - Department of Surgery, Shiga University of Medical Science, Setatsukinowa-cho, 
      Otsu, Shiga, 520-2192, Japan.
LA  - eng
PT  - Journal Article
DEP - 20220401
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
SB  - IM
MH  - *Diabetes Mellitus, Type 2/drug therapy/etiology/surgery
MH  - Drug Costs
MH  - Gastrectomy/methods
MH  - Humans
MH  - *Hypertension/surgery
MH  - Japan
MH  - *Laparoscopy/methods
MH  - Obesity/etiology/surgery
MH  - *Obesity, Morbid/surgery
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Drug treatment costs
OT  - Obesity-related diseases
OT  - Sleeve gastrectomy
OT  - Type 2 diabetes mellitus
EDAT- 2022/04/02 06:00
MHDA- 2022/05/10 06:00
CRDT- 2022/04/01 12:10
PHST- 2021/12/28 00:00 [received]
PHST- 2022/03/22 00:00 [accepted]
PHST- 2022/03/21 00:00 [revised]
PHST- 2022/04/02 06:00 [pubmed]
PHST- 2022/05/10 06:00 [medline]
PHST- 2022/04/01 12:10 [entrez]
AID - 10.1007/s11695-022-06036-6 [pii]
AID - 10.1007/s11695-022-06036-6 [doi]
PST - ppublish
SO  - Obes Surg. 2022 Jun;32(6):1831-1841. doi: 10.1007/s11695-022-06036-6. Epub 2022 
      Apr 1.