PMID- 35365390
OWN - NLM
STAT- MEDLINE
DCOM- 20221215
LR  - 20221222
IS  - 0219-3108 (Electronic)
IS  - 1015-9584 (Linking)
VI  - 46
IP  - 1
DP  - 2023 Jan
TI  - The Geriatric Nutritional Risk Index predicts amputation after infrapopliteal 
      angioplasty in critical limb ischemia patients.
PG  - 250-253
LID - S1015-9584(22)00291-3 [pii]
LID - 10.1016/j.asjsur.2022.03.049 [doi]
AB  - OBJECTIVE: To validate the Critical Limb Ischemia Frailty Index (CLIFI), and to 
      identify independent predictors of 2-year amputation-free survival after 
      infrapopliteal endovascular treatment for chronic limb-threatening ischemia 
      (CLTI) in Thai patients. METHODS: This retrospective study was conducted during 
      the June 2014 to February 2017 study period. CLTI patients treated with 
      infrapopliteal angioplasty were enrolled and analyzed. A patient was defined as 
      CLIFI positive if two or more of the following criteria were present: Geriatric 
      Nutritional Risk Index (GNRI) < 89.8, low skeletal muscle mass index 
      (<6.87 kg/m(2) in males, and <5.46 kg/m(2) in females), and/or non-ambulatory 
      status. Kaplan-Meier survival analysis was used to assess 2-year amputation-free 
      survival (AFS), and comparisons were performed using log-rank test. Univariate 
      and multivariate Cox proportional hazards models were used to analyze for 
      significant and independent association, respectively, between preoperative 
      characteristics and AFS. RESULTS: A total of 266 patients and 286 limbs were 
      included. Forty (15.0%) patients were CLIFI positive, and 226 (85.0%) patients 
      were CLIFI negative. The 2-year amputation-free survival rate was 90.3% in the 
      CLIFI positive group, and 86.6% in the CLIFI negative group (p = 0.59). 
      Multivariate analysis revealed the GNRI to be an independent risk factor for 
      amputation within two years after infrapopliteal revascularization (adjusted 
      hazard ratio: 4.87, 95% confidence interval: 1.20-19.70; p = 0.02). CONCLUSIONS: 
      The GNRI was found to independently predict 2-year amputation after 
      infrapopliteal angioplasty in Thai CLTI patients; however, the CLIFI was not 
      found to significantly predict 2-year amputation in this patient population.
CI  - Copyright (c) 2022 Asian Surgical Association and Taiwan Robotic Surgery 
      Association. Published by Elsevier B.V. All rights reserved.
FAU - Ruangsetakit, Chanean
AU  - Ruangsetakit C
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Navikaputra, Sanit
AU  - Navikaputra S
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Pruekprasert, Kanin
AU  - Pruekprasert K
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Prapassaro, Tossapol
AU  - Prapassaro T
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Puangpunngam, Nattawut
AU  - Puangpunngam N
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Hongku, Kiattisak
AU  - Hongku K
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Hahtapornsawan, Suteekhanit
AU  - Hahtapornsawan S
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Chinsakchai, Khamin
AU  - Chinsakchai K
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Wongwanit, Chumpol
AU  - Wongwanit C
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand.
FAU - Sermsathanasawadi, Nuttawut
AU  - Sermsathanasawadi N
AD  - Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj 
      Hospital, Mahidol University, Bangkok, Thailand. Electronic address: 
      nuttawut@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20220329
PL  - Netherlands
TA  - Asian J Surg
JT  - Asian journal of surgery
JID - 8900600
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - Aged
MH  - Chronic Limb-Threatening Ischemia
MH  - Limb Salvage/adverse effects
MH  - Ischemia/surgery/etiology
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Angioplasty
MH  - Risk Factors
MH  - *Peripheral Arterial Disease/surgery
MH  - *Endovascular Procedures
OTO - NOTNLM
OT  - Amputation
OT  - Angioplasty
OT  - Chronic limb-threatening ischemia
OT  - Frailty
OT  - Nutrition
COIS- Declaration of competing interest None.
EDAT- 2022/04/03 06:00
MHDA- 2022/12/16 06:00
CRDT- 2022/04/02 05:24
PHST- 2022/01/04 00:00 [received]
PHST- 2022/03/08 00:00 [revised]
PHST- 2022/03/17 00:00 [accepted]
PHST- 2022/04/03 06:00 [pubmed]
PHST- 2022/12/16 06:00 [medline]
PHST- 2022/04/02 05:24 [entrez]
AID - S1015-9584(22)00291-3 [pii]
AID - 10.1016/j.asjsur.2022.03.049 [doi]
PST - ppublish
SO  - Asian J Surg. 2023 Jan;46(1):250-253. doi: 10.1016/j.asjsur.2022.03.049. Epub 
      2022 Mar 29.