PMID- 35369645
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220405
IS  - 1642-395X (Print)
IS  - 2299-0046 (Electronic)
IS  - 1642-395X (Linking)
VI  - 39
IP  - 1
DP  - 2022 Feb
TI  - Investigating the association of atopy and aeroallergen sensitization and chronic 
      spontaneous urticaria.
PG  - 121-125
LID - 10.5114/ada.2022.113805 [doi]
AB  - INTRODUCTION: Chronic spontaneous urticaria (CSU) is a common skin allergic 
      reaction with an unknown mechanism. There is inadequate evidence to support the 
      role of aeroallergen sensitization in CSU. AIM: The present study was conducted 
      to investigate the association between the aeroallergen sensitivity and CSU. 
      MATERIAL AND METHODS: In this cross-sectional study, 91 patients with CSU were 
      recruited. Information on demographic characteristics was collected. The skin 
      prick test (SPT) for most prevalent aeroallergens and pulmonary function test 
      (PFT) were performed and the results were clinically matched to investigate the 
      allergic rhinitis (AR) and asthma. Total serum immunoglobulin E (IgE) 
      concentration was analysed in the subjects for the presence of atopy. RESULTS: 
      Ninety one patients (75 of them were females) were enrolled in the study (with a 
      mean age of 36.90 +/-12.93 years). SPT result was positive in 75 (82.4%) subjects. 
      Weeds (67 cases, 73.6%), trees (61 cases, 67%), and dust mites (55 cases, 60.4%) 
      were the most common pollens in the positive SPT samples. Thirty-seven (40.7%) of 
      the patients had allergic rhinitis. There was a statistically significant 
      association between the presence of AR and positive SPT result (p = 0.002). Eight 
      patients had allergic asthma and 45 (49.4%) of the patients had a total serum IgE 
      level of more than 100 IU/ml. CONCLUSIONS: Our results indicated a clear 
      association between the presence of aeroallergen sensitivity and development of 
      CSU. AR exists as a co-morbidity of CSU.
CI  - Copyright (c) 2022 Termedia.
FAU - Esmaeilzadeh, Hossein
AU  - Esmaeilzadeh H
AD  - Allergy Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.
AD  - Department of Allergy and Clinical Immunology, Namazi Hospital, Shiraz University 
      of Medical Sciences, Shiraz, Iran.
FAU - Eskandarisani, Mehrdad
AU  - Eskandarisani M
AD  - Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
FAU - Nabavizadeh, Hesamedin
AU  - Nabavizadeh H
AD  - Allergy Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.
AD  - Department of Allergy and Clinical Immunology, Namazi Hospital, Shiraz University 
      of Medical Sciences, Shiraz, Iran.
FAU - Alyasin, Soheila
AU  - Alyasin S
AD  - Allergy Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.
AD  - Department of Allergy and Clinical Immunology, Namazi Hospital, Shiraz University 
      of Medical Sciences, Shiraz, Iran.
FAU - Vali, Mouhebat
AU  - Vali M
AD  - Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
FAU - Mortazavi, Negar
AU  - Mortazavi N
AD  - Department of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical 
      Sciences, Shiraz, Iran.
LA  - eng
PT  - Journal Article
DEP - 20220228
PL  - Poland
TA  - Postepy Dermatol Alergol
JT  - Postepy dermatologii i alergologii
JID - 101168357
PMC - PMC8953881
OTO - NOTNLM
OT  - aeroallergens
OT  - allergy
OT  - atopy
OT  - skin prick test
OT  - urticaria
COIS- The authors declare no conflict of interest.
EDAT- 2022/04/05 06:00
MHDA- 2022/04/05 06:01
PMCR- 2022/02/01
CRDT- 2022/04/04 05:22
PHST- 2020/06/07 00:00 [received]
PHST- 2020/11/14 00:00 [accepted]
PHST- 2022/04/04 05:22 [entrez]
PHST- 2022/04/05 06:00 [pubmed]
PHST- 2022/04/05 06:01 [medline]
PHST- 2022/02/01 00:00 [pmc-release]
AID - 46466 [pii]
AID - 10.5114/ada.2022.113805 [doi]
PST - ppublish
SO  - Postepy Dermatol Alergol. 2022 Feb;39(1):121-125. doi: 10.5114/ada.2022.113805. 
      Epub 2022 Feb 28.