PMID- 35382684
OWN - NLM
STAT- MEDLINE
DCOM- 20220530
LR  - 20220530
IS  - 1651-2251 (Electronic)
IS  - 0001-6489 (Linking)
VI  - 142
IP  - 3-4
DP  - 2022 Mar-Apr
TI  - A retrospective study of 20 patients with Kimura's disease from China.
PG  - 357-362
LID - 10.1080/00016489.2022.2055139 [doi]
AB  - BACKGROUND: Kimura's disease (KD) is an eosinophilic proliferative lymphoid 
      disease with rare incidence rate and nonspecific clinical symptoms. OBJECTIVES: 
      To investigate the clinical characteristics, diagnosis, treatment, and prognosis 
      of KD. MATERIALS AND METHODS: The clinical manifestations, laboratory 
      examination, imaging examination, proposed treatment, and prognosis of 20 
      patients with KD treated in our hospital were retrospectively analyzed. RESULTS: 
      All cases showed painless masses. The proportion of peripheral blood eosinophils 
      rose in 18 cases (90%), the eosinophil count increased in 14 cases (70%) and the 
      serum immunoglobulin E (IgE) levels were significantly increased in 5 patients 
      (100%). Pathological examination revealed follicular hyperplasia, eosinophils 
      infiltration, and tiny vessels proliferation in KD samples. CONCLUSIONS: KD 
      should be considered when the patients suffered head and neck subcutaneous 
      painless mass, increased peripheral blood eosinophils and raised serum IgE level. 
      Pathological examination is the golden standard for diagnosing KD. Surgical 
      intervention, medical treatments, and radiotherapy may be effective for KD 
      treatment. SIGNIFICANCE: This study might shed a light on improving the diagnosis 
      and treatment for KD.
FAU - Zhuang, Suling
AU  - Zhuang S
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
FAU - Chen, Xiaoqiang
AU  - Chen X
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
FAU - Chen, Wei
AU  - Chen W
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
FAU - Li, Chen
AU  - Li C
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
FAU - Wang, Taiqin
AU  - Wang T
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
FAU - Lin, Qin
AU  - Lin Q
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
FAU - Wang, Desheng
AU  - Wang D
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, Fujian, 
      PR China.
LA  - eng
PT  - Journal Article
DEP - 20220405
PL  - England
TA  - Acta Otolaryngol
JT  - Acta oto-laryngologica
JID - 0370354
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - *Angiolymphoid Hyperplasia with Eosinophilia/drug therapy/therapy
MH  - China/epidemiology
MH  - Humans
MH  - Immunoglobulin E
MH  - *Kimura Disease
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Kimura's disease
OT  - eosinophilia
OT  - eosinophilic lymphoid granuloma
OT  - painless mass
OT  - treatment
EDAT- 2022/04/07 06:00
MHDA- 2022/05/31 06:00
CRDT- 2022/04/06 05:20
PHST- 2022/04/07 06:00 [pubmed]
PHST- 2022/05/31 06:00 [medline]
PHST- 2022/04/06 05:20 [entrez]
AID - 10.1080/00016489.2022.2055139 [doi]
PST - ppublish
SO  - Acta Otolaryngol. 2022 Mar-Apr;142(3-4):357-362. doi: 
      10.1080/00016489.2022.2055139. Epub 2022 Apr 5.