PMID- 35383867
OWN - NLM
STAT- MEDLINE
DCOM- 20220407
LR  - 20220407
IS  - 2185-2243 (Electronic)
IS  - 0385-0005 (Linking)
VI  - 47
IP  - 1
DP  - 2022 Apr 20
TI  - ANCA-Associated Vasculitis in a Patient with Chronic Thromboembolic Pulmonary 
      Hypertension.
PG  - 26-30
AB  - An 82-year-old woman with a history of chronic thromboembolic pulmonary 
      hypertension (CTEPH) presented with malaise, left facial nerve paralysis and the 
      positive seroconversion of myeloperoxidase (MPO)-antineutrophil cytoplasmic 
      antibody (ANCA). She was diagnosed with ANCA-associated vasculitis (AAV). 
      Administration of corticosteroids significantly improved her symptoms, with a 
      decline in the serum MPOANCA level. Ten months later than the initial 
      presentation, she developed an AAV exacerbation with lung infiltration and 
      pericardial effusion, which improved with high-dose corticosteroid therapy. To 
      date, a limited number of AAV cases concomitant with pulmonary hypertension have 
      been reported. The case report presented herein suggests a potential role for 
      CTEPH in the development of AAV.
FAU - Okada, Naoki
AU  - Okada N
FAU - Takiguchi, Hiroto
AU  - Takiguchi H
AD  - Division of Pulmonary Medicine, Department of Medicine, Tokai University School 
      of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. 
      takihiroto@gmail.com.
FAU - Suzuki, Wataru
AU  - Suzuki W
FAU - Okazaki, Eriko
AU  - Okazaki E
FAU - Yoshikawa, Tomohiro
AU  - Yoshikawa T
FAU - Takeuchi, Tomoe
AU  - Takeuchi T
FAU - Tanaka, Jun
AU  - Tanaka J
FAU - Kitahara, Asako
AU  - Kitahara A
FAU - Niimi, Kyoko
AU  - Niimi K
FAU - Hayama, Naoki
AU  - Hayama N
FAU - Ito, Yoko
AU  - Ito Y
FAU - Oguma, Tsuyoshi
AU  - Oguma T
FAU - Asano, Koichiro
AU  - Asano K
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20220420
PL  - Japan
TA  - Tokai J Exp Clin Med
JT  - The Tokai journal of experimental and clinical medicine
JID - 7704186
RN  - 0 (Antibodies, Antineutrophil Cytoplasmic)
SB  - IM
MH  - Aged, 80 and over
MH  - *Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/complications
MH  - Antibodies, Antineutrophil Cytoplasmic
MH  - Female
MH  - Humans
MH  - *Hypertension, Pulmonary/drug therapy/etiology
EDAT- 2022/04/07 06:00
MHDA- 2022/04/08 06:00
CRDT- 2022/04/06 09:11
PHST- 2021/09/30 00:00 [received]
PHST- 2021/12/06 00:00 [accepted]
PHST- 2022/04/06 09:11 [entrez]
PHST- 2022/04/07 06:00 [pubmed]
PHST- 2022/04/08 06:00 [medline]
PST - epublish
SO  - Tokai J Exp Clin Med. 2022 Apr 20;47(1):26-30.