PMID- 35384548
OWN - NLM
STAT- MEDLINE
DCOM- 20220614
LR  - 20220727
IS  - 1534-3170 (Electronic)
IS  - 1523-3782 (Linking)
VI  - 24
IP  - 6
DP  - 2022 Jun
TI  - STEMI: Considerations for Left Main Culprit Lesions.
PG  - 645-651
LID - 10.1007/s11886-022-01685-6 [doi]
AB  - PURPOSE OF REVIEW: There is a paucity of data regarding the prevalence, clinical 
      characteristics, and outcomes of patients presenting with ST elevation myocardial 
      infarction (STEMI) due to left main (LM) culprit vessel. RECENT FINDINGS: LM 
      culprit STEMI (LMCSTEMI) is an uncommon, but frequently catastrophic event. Prior 
      meta-analyses and registries have described a varying prevalence of LMCSTEMI, 
      associated cardiogenic shock, and in-hospital mortality among those surviving to 
      hospital presentation. These observed clinical discrepancies may be partially 
      attributable to diverse clinical and angiographical subsets among this STEMI 
      population. STEMI due to LM culprit artery disease represents a clinically 
      high-risk subset of patients with substantial in-hospital mortality. In this 
      paper, we summarize the available clinical data pertaining to STEMI with LM 
      culprit, discuss unique ECG characteristics, and discuss contemporary 
      revascularization therapy. We also report the preliminary findings from a 
      contemporary, STEMI database describing clinical characteristics and 
      angiographically defined subsets of LM culprit STEMI.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Ahmed, Ameera
AU  - Ahmed A
AD  - Cardiovascular Institute of Northern Colorado, Banner Health, Loveland, USA.
FAU - Aguirre, Frank V
AU  - Aguirre FV
AD  - Prairie Education and Research Cooperative, Springfield, IL, USA.
FAU - Chambers, Jenny
AU  - Chambers J
AD  - Prairie Education and Research Cooperative, Springfield, IL, USA.
FAU - Sharkey, Scott W
AU  - Sharkey SW
AD  - Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, 
      Minneapolis, USA.
FAU - Tannenbaum, Mark A
AU  - Tannenbaum MA
AD  - Iowa Heart Center, West Des Moines, USA.
FAU - Yildiz, Mehmet
AU  - Yildiz M
AD  - The Carl and Edyth Lindner Center for Research and Education, The Christ 
      Hospital, Cincinnati, OH, USA.
FAU - Garberich, Ross
AU  - Garberich R
AD  - Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, 
      Minneapolis, USA.
FAU - Garcia, Santiago
AU  - Garcia S
AD  - Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, 
      Minneapolis, USA.
FAU - Henry, Timothy D
AU  - Henry TD
AD  - The Carl and Edyth Lindner Center for Research and Education, The Christ 
      Hospital, Cincinnati, OH, USA. Tim.Henry@thechristhospital.com.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220406
PL  - United States
TA  - Curr Cardiol Rep
JT  - Current cardiology reports
JID - 100888969
SB  - IM
MH  - *Coronary Artery Disease/etiology
MH  - Humans
MH  - *Percutaneous Coronary Intervention/adverse effects
MH  - Registries
MH  - *ST Elevation Myocardial Infarction/therapy
MH  - Shock, Cardiogenic/etiology
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Left main coronary disease
OT  - Midwest STEMI Consortium
OT  - Primary PCI: primary percutaneous coronary revascularization
OT  - STEMI: ST elevation myocardial infarction
EDAT- 2022/04/07 06:00
MHDA- 2022/06/15 06:00
CRDT- 2022/04/06 12:06
PHST- 2022/03/08 00:00 [accepted]
PHST- 2022/04/07 06:00 [pubmed]
PHST- 2022/06/15 06:00 [medline]
PHST- 2022/04/06 12:06 [entrez]
AID - 10.1007/s11886-022-01685-6 [pii]
AID - 10.1007/s11886-022-01685-6 [doi]
PST - ppublish
SO  - Curr Cardiol Rep. 2022 Jun;24(6):645-651. doi: 10.1007/s11886-022-01685-6. Epub 
      2022 Apr 6.