PMID- 35399065
OWN - NLM
STAT- MEDLINE
DCOM- 20220412
LR  - 20220414
IS  - 1471-2393 (Electronic)
IS  - 1471-2393 (Linking)
VI  - 22
IP  - 1
DP  - 2022 Apr 10
TI  - Study on the correlation between homocysteine-related dietary patterns and 
      gestational diabetes mellitus:a reduced-rank regression analysis study.
PG  - 306
LID - 10.1186/s12884-022-04656-5 [doi]
LID - 306
AB  - BACKGROUND: This study aimed to evaluate the association between 
      homocysteine-related dietary patterns and gestational diabetes mellitus. METHODS: 
      A total of 488 pregnant women at 24-28 weeks of gestation between January 2019 
      and December 2020 were included. Demographic characteristics, dietary intake, and 
      multivitamin supplement intake information were collected using a food frequency 
      questionnaire (FFQ); fasting venous blood samples were collected for serum index 
      detection. Serum homocysteine (Hcy), folic acid, and B12 were selected as 
      response variables, and hyperhomocysteinemia (hHcy)-related dietary patterns were 
      extracted using the reduced rank regression.. The relationship between the score 
      of hHcy-related dietary patterns and GDM was analyzed using a multivariate 
      logistic regression model. RESULTS: Three hHcy-related dietary patterns were 
      extracted. Only mode 2 had a positive and significant relationship with the risk 
      of developing GDM. After adjusting for confounding factors, the risk of GDM was 
      significantly increased in the highest quartile array compared with the lowest 
      quartile of the pattern (OR = 2.96, 95% Confidence Interval: 0.939-9.356, 
      P = 0.004). There was no significant correlation between dietary pattern 1 and 
      GDM risk (P > 0.05). CONCLUSIONS: Homocysteine-related dietary patterns were 
      positively associated with gestational diabetes mellitus. Adjusting dietary 
      patterns may contribute to the intervention and prevention of GDM.
CI  - (c) 2022. The Author(s).
FAU - Liu, Yu-Hong
AU  - Liu YH
AD  - Department of obstetrics and gynecology, Seventh People's Hospital of shanghai 
      University of Traditional Chinese Medicine, Shanghai, 200137, China.
FAU - Lu, Ling-Peng
AU  - Lu LP
AD  - Department of Clinical lab, Seventh People's Hospital of shanghai University of 
      Traditional Chinese Medicine, Shanghai, 200137, China.
FAU - Yi, Min-Hui
AU  - Yi MH
AD  - Department of obstetrics and gynecology, Seventh People's Hospital of shanghai 
      University of Traditional Chinese Medicine, Shanghai, 200137, China.
FAU - Shen, Chun-Yan
AU  - Shen CY
AD  - Department of Nutrition, Seventh People's Hospital of shanghai University of 
      Traditional Chinese Medicine, Shanghai, 200137, China.
FAU - Lu, Gu-Qin
AU  - Lu GQ
AD  - Department of Nutrition, Seventh People's Hospital of shanghai University of 
      Traditional Chinese Medicine, Shanghai, 200137, China.
FAU - Jia, Jie
AU  - Jia J
AD  - Department of Nutrition, School of Medicine Shanghai Jiao Tong University, 
      Shanghai, 200137, China.
FAU - Wu, Hui
AU  - Wu H
AD  - Department of Nutrition, Seventh People's Hospital of shanghai University of 
      Traditional Chinese Medicine, Shanghai, 200137, China. 877761520@qq.com.
LA  - eng
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
GR  - 2019LK042/University-level project of Shanghai University of Traditional Chinese 
      Medicine/
PT  - Journal Article
DEP - 20220410
PL  - England
TA  - BMC Pregnancy Childbirth
JT  - BMC pregnancy and childbirth
JID - 100967799
RN  - 0LVT1QZ0BA (Homocysteine)
SB  - IM
MH  - *Diabetes, Gestational/epidemiology/prevention & control
MH  - Diet
MH  - Fasting
MH  - Female
MH  - Homocysteine
MH  - Humans
MH  - Pregnancy
MH  - Regression Analysis
MH  - Risk Factors
PMC - PMC8994885
OTO - NOTNLM
OT  - Clinical study
OT  - Dietary patterns
OT  - Gestational diabetes mellitus
OT  - Homocysteine
OT  - Reduced rank regression
COIS- The authors declare that they have no competing interests.
EDAT- 2022/04/12 06:00
MHDA- 2022/04/13 06:00
PMCR- 2022/04/10
CRDT- 2022/04/11 05:04
PHST- 2021/08/26 00:00 [received]
PHST- 2022/04/01 00:00 [accepted]
PHST- 2022/04/11 05:04 [entrez]
PHST- 2022/04/12 06:00 [pubmed]
PHST- 2022/04/13 06:00 [medline]
PHST- 2022/04/10 00:00 [pmc-release]
AID - 10.1186/s12884-022-04656-5 [pii]
AID - 4656 [pii]
AID - 10.1186/s12884-022-04656-5 [doi]
PST - epublish
SO  - BMC Pregnancy Childbirth. 2022 Apr 10;22(1):306. doi: 10.1186/s12884-022-04656-5.