PMID- 35405338
OWN - NLM
STAT- MEDLINE
DCOM- 20220823
LR  - 20221006
IS  - 1878-1632 (Electronic)
IS  - 1529-9430 (Linking)
VI  - 22
IP  - 9
DP  - 2022 Sep
TI  - Outcomes of cervical disc replacement in patients with neck pain greater than arm 
      pain.
PG  - 1481-1489
LID - S1529-9430(22)00147-4 [pii]
LID - 10.1016/j.spinee.2022.04.001 [doi]
AB  - BACKGROUND CONTEXT: Although anterior cervical discectomy and fusion is believed 
      to positively impact a patient's radicular symptoms as well as axial neck pain, 
      the outcomes of cervical disc replacement (CDR) with regards to neck pain 
      specifically have not been established. PURPOSE: Primary: to assess clinical 
      improvement following CDR in patients with neck pain greater than arm pain. 
      Secondary: to compare the clinical outcomes between patients undergoing CDR for 
      predominant neck pain (pNP), predominant arm pain (pAP), and equal neck and arm 
      pain (ENAP). STUDY DESIGN: Retrospective review of prospectively collected data. 
      PATIENT SAMPLE: Patients who had undergone one- or two-level CDR for the 
      treatment of degenerative cervical pathology and had a minimum of 6-month 
      follow-up were included and stratified into three cohorts based on their 
      predominant location of pain: pNP, pAP, and ENAP. OUTCOME MEASURES: 
      Patient-reported outcomes: Neck Disability Index (NDI), Visual Analog Scale (VAS) 
      neck and arm, Short Form 12-Item Physical Health Score (SF12-PHS), Short Form 
      12-Item Mental Health Score (SF12-MHS), minimal clinically important difference 
      (MCID). METHODS: Changes in Patient-reported outcomes from preoperative values to 
      early (<6 months) and late (>/=6 months) postoperative timepoints were analyzed 
      within each of the three groups. The percentage of patients achieving MCID was 
      also evaluated. RESULTS: One hundred twenty-five patients (52 pNP, 30 pAP, 43 
      ENAP) were included. The pNP cohort demonstrated significant improvements in 
      early and late NDI and VAS-Neck, early SF-12 MCS, and late SF-12 PCS. The pAP and 
      ENAP cohorts demonstrated significant improvements in all PROMs, including NDI, 
      VAS-Neck, VAS-Arm, SF-12 PCS, and SF-12 MCS, at both the early and late 
      timepoints. No statistically significant differences were found in the MCID 
      achievement rates for NDI, VAS-Neck, SF-12 PCS, and SF-12 MCS at the late 
      timepoint amongst the three groups. CONCLUSIONS: CDR leads to comparable 
      improvement in neck pain and disability in patients presenting with neck pain 
      greater than arm pain and meeting specific clinical and radiographic criteria.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Shahi, Pratyush
AU  - Shahi P
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA.
FAU - Vaishnav, Avani S
AU  - Vaishnav AS
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA.
FAU - Lee, Ryan
AU  - Lee R
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA.
FAU - Mai, Eric
AU  - Mai E
AD  - Weill Cornell Medical College, New York, NY, USA.
FAU - Steinhaus, Michael E
AU  - Steinhaus ME
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA.
FAU - Huang, Russel
AU  - Huang R
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA; Weill Cornell Medical College, New York, NY, USA.
FAU - Albert, Todd
AU  - Albert T
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA; Weill Cornell Medical College, New York, NY, USA.
FAU - Iyer, Sravisht
AU  - Iyer S
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA; Weill Cornell Medical College, New York, NY, USA.
FAU - Sheha, Evan D
AU  - Sheha ED
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA; Weill Cornell Medical College, New York, NY, USA.
FAU - Dowdell, James E
AU  - Dowdell JE
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA; Weill Cornell Medical College, New York, NY, USA.
FAU - Qureshi, Sheeraz A
AU  - Qureshi SA
AD  - Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 
      USA; Weill Cornell Medical College, New York, NY, USA. Electronic address: 
      sheerazqureshimd@gmail.com.
LA  - eng
GR  - UL1 TR002384/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20220408
PL  - United States
TA  - Spine J
JT  - The spine journal : official journal of the North American Spine Society
JID - 101130732
SB  - IM
MH  - Cervical Vertebrae/surgery
MH  - Disability Evaluation
MH  - Diskectomy
MH  - Humans
MH  - *Neck Pain/etiology/surgery
MH  - *Spinal Fusion
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Cervical disc replacement
OT  - Mental component score
OT  - Minimal clinically important difference
OT  - Neck disability index
OT  - Patient-reported outcomes
OT  - Physical component score
OT  - Predominant neck pain Visual analog scale
COIS- Declarations of competing interests The authors report no conflicts of interest 
      relevant to the topic of this study.
EDAT- 2022/04/12 06:00
MHDA- 2022/08/24 06:00
CRDT- 2022/04/11 20:11
PHST- 2022/01/14 00:00 [received]
PHST- 2022/03/19 00:00 [revised]
PHST- 2022/04/03 00:00 [accepted]
PHST- 2022/04/12 06:00 [pubmed]
PHST- 2022/08/24 06:00 [medline]
PHST- 2022/04/11 20:11 [entrez]
AID - S1529-9430(22)00147-4 [pii]
AID - 10.1016/j.spinee.2022.04.001 [doi]
PST - ppublish
SO  - Spine J. 2022 Sep;22(9):1481-1489. doi: 10.1016/j.spinee.2022.04.001. Epub 2022 
      Apr 8.