PMID- 35405624 OWN - NLM STAT- MEDLINE DCOM- 20220621 LR - 20220621 IS - 1873-5800 (Electronic) IS - 0968-0160 (Linking) VI - 36 DP - 2022 Jun TI - Comparison of the clinical and patient-reported outcomes between medial stabilized and posterior stabilized total knee arthroplasty: A systematic review and meta-analysis. PG - 9-19 LID - S0968-0160(22)00040-0 [pii] LID - 10.1016/j.knee.2022.03.010 [doi] AB - BACKGROUND: Total knee arthroplasty (TKA) is effective in relieving pain and improving function in patients with end-stage knee osteoarthritis. Both medial stabilized total knee arthroplasty (MS-TKA) and posterior stabilized total knee arthroplasty (PS-TKA) can achieve satisfactory clinical results, but comparisons between MS-TKA and PS-TKA have yielded contradictory conclusions. This systematic review and meta-analysis were performed to investigate the differences in clinical and patient-reported outcomes (PROMs) between MS-TKA and PS-TKA. METHODS: In December 2020, systematic searches of the following databases were undertaken: Pubmed, Embase, Cochrane Library, Clinical Trials.gov. Studies with PROMs comparing MS-TKA to PS-TKA were included. Meta-analysis was conducted for range of motion (ROM), Knee Society Score (KSS), Knee Society Functional Score (KFS), Forgotten Joint Score (FJS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Oxford Knee Score (OKS). RESULTS: There were 17 studies included in this review, 13 studies used for quantitative analysis, and 4 studies used for qualitative synthesis. Meta-analysis concluded that the WOMAC mean difference (MD) for MS-TKA was 1.55 higher than for PS-TKA (MD = -1.55; 95 %CI = -2.45 to -0.64, P = 0.0008); however, this difference was less than the minimum clinically important difference (MCID) value of 15. Assessment using the OKS determined that the MD for PS-TKA was 0.58 higher than for MS-TKA (MD = 0.58; 95 %CI = 0.25 to 0.91, P = 0.0006); again, this MD was less than the MCID value of 5. There were no significant differences between MS-TKA and PS-TKA when assessed by ROM (P = 0.23), KSS (P = 0.13), KFS (P = 0.61), or FJS (P = 0.22). CONCLUSION: Derived from numerous sources, utilizing a multitude of validated functional and patient-reported outcome assessment tools, there was no clinically evident advantage of MS-TKA compared to PS-TKA. REGISTRATION: The registration number on PROSPERO is CRD42021228555. CI - Copyright (c) 2022 Elsevier B.V. All rights reserved. FAU - Liu, Xiaolong AU - Liu X AD - Tianjin Medical University, No. 22 Qixiangtai Rd, Heping District, Tianjin 300041 China. Electronic address: Lxiaolong0108@163.com. FAU - Liu, Yang AU - Liu Y AD - Tianjin Medical University, No. 22 Qixiangtai Rd, Heping District, Tianjin 300041 China. Electronic address: djso2005@sina.cn. FAU - Li, Bing AU - Li B AD - Tianjin Hospital, No. 406 Jiefang South Rd, Hexi District, Tianjin 300211, China. Electronic address: braveman1982@163.com. FAU - Wang, Lei AU - Wang L AD - Tianjin Hospital, No. 406 Jiefang South Rd, Hexi District, Tianjin 300211, China. Electronic address: wanglei12074@sina.com. FAU - Wang, Yuanlin AU - Wang Y AD - Tianjin Medical University, No. 22 Qixiangtai Rd, Heping District, Tianjin 300041 China. Electronic address: wangyuandekeyan@163.com. FAU - Liu, Jun AU - Liu J AD - Tianjin Hospital, No. 406 Jiefang South Rd, Hexi District, Tianjin 300211, China. Electronic address: tjliujun0307@163.com. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PT - Systematic Review DEP - 20220408 PL - Netherlands TA - Knee JT - The Knee JID - 9430798 SB - IM MH - *Arthroplasty, Replacement, Knee/methods MH - Humans MH - Knee Joint/surgery MH - *Knee Prosthesis MH - *Osteoarthritis, Knee/surgery MH - Patient Reported Outcome Measures MH - Range of Motion, Articular OTO - NOTNLM OT - Clinical and patient-reported outcomes OT - Knee osteoarthritis OT - Medial stabilized OT - Posterior stabilized OT - Total knee arthroplasty COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/04/12 06:00 MHDA- 2022/06/22 06:00 CRDT- 2022/04/11 20:17 PHST- 2021/06/12 00:00 [received] PHST- 2021/12/28 00:00 [revised] PHST- 2022/03/21 00:00 [accepted] PHST- 2022/04/12 06:00 [pubmed] PHST- 2022/06/22 06:00 [medline] PHST- 2022/04/11 20:17 [entrez] AID - S0968-0160(22)00040-0 [pii] AID - 10.1016/j.knee.2022.03.010 [doi] PST - ppublish SO - Knee. 2022 Jun;36:9-19. doi: 10.1016/j.knee.2022.03.010. Epub 2022 Apr 8.