PMID- 35409925 OWN - NLM STAT- MEDLINE DCOM- 20220413 LR - 20221207 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 19 IP - 7 DP - 2022 Apr 2 TI - Effectiveness of Strategies for Nutritional Therapy for Patients with Type 2 Diabetes and/or Hypertension in Primary Care: A Systematic Review and Meta-Analysis. LID - 10.3390/ijerph19074243 [doi] LID - 4243 AB - A central aspect to the management of type 2 Diabetes Mellitus (T2DM) and hypertension is promoting a healthy lifestyle, and nutritional therapy (NT) can support patients achieving glycemic control and blood pressure targets. This systematic review aimed to evaluate the effectiveness of NT in the management of patients with T2DM and/or hypertension in primary care. Primary outcomes were HbA1c, systolic blood pressure (SBP) and diastolic blood pressure (DBP). Thirty-nine studies were included, thirty on T2DM and nine on hypertension. With a moderate quality of evidence, educational/counseling programs and food replacement programs in primary care likely reduce HbA1c on patients with T2DM (mean difference (MD): -0.37, 95% CI: -0.57 to -0.17, 7437 patients, 27 studies; MD: -0.54, 95% CI: -0.75 to -0.32, 440 patients, 2 studies, respectively). Mediterranean diet for T2DM was accessed by one study, and no difference between the groups was found. Educational and counseling programs likely reduce DBP in patients with hypertension (MD: -1.79, 95% CI: -3.46, -0.12, 2840 patients, 9 studies, moderate quality of the evidence), but the effect in SBP was unclear due to risk of bias and imprecision. Nutritional therapy strategies (i.e., educational/counseling programs and food replacement programs) in primary care improved HbA1c in patients with T2DM and DBP in individuals with hypertension. FAU - Simoes Correa Galendi, Julia AU - Simoes Correa Galendi J AUID- ORCID: 0000-0002-4832-7294 AD - Institute of Health Economics and Clinical Epidemiology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50924 Cologne, Germany. FAU - Leite, Renata Giacomini Occhiuto Ferreira AU - Leite RGOF AD - Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), 18618687 Botucatu, Brazil. FAU - Banzato, Luisa Rocco AU - Banzato LR AD - Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), 18618687 Botucatu, Brazil. FAU - Nunes-Nogueira, Vania Dos Santos AU - Nunes-Nogueira VDS AUID- ORCID: 0000-0001-9316-4167 AD - Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), 18618687 Botucatu, Brazil. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Review PT - Systematic Review DEP - 20220402 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 RN - 0 (Glycated Hemoglobin A) SB - IM MH - Blood Pressure MH - *Diabetes Mellitus, Type 2/therapy MH - Glycated Hemoglobin MH - Humans MH - *Hypertension/therapy MH - Primary Health Care PMC - PMC8998242 OTO - NOTNLM OT - chronic disease OT - health services research OT - hypertensions OT - nutrition therapy OT - primary care OT - type 2 diabetes mellitus COIS- The authors declare no conflict of interest. EDAT- 2022/04/13 06:00 MHDA- 2022/04/14 06:00 PMCR- 2022/04/02 CRDT- 2022/04/12 01:15 PHST- 2022/01/18 00:00 [received] PHST- 2022/03/05 00:00 [revised] PHST- 2022/03/07 00:00 [accepted] PHST- 2022/04/12 01:15 [entrez] PHST- 2022/04/13 06:00 [pubmed] PHST- 2022/04/14 06:00 [medline] PHST- 2022/04/02 00:00 [pmc-release] AID - ijerph19074243 [pii] AID - ijerph-19-04243 [pii] AID - 10.3390/ijerph19074243 [doi] PST - epublish SO - Int J Environ Res Public Health. 2022 Apr 2;19(7):4243. doi: 10.3390/ijerph19074243.