PMID- 35411276 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220413 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 14 IP - 3 DP - 2022 Mar TI - Acute Ischemic Stroke Due to Spontaneous Internal Carotid Artery Dissection in a Human Leukocyte Antigen (HLA) B27 Young Male. PG - e22963 LID - 10.7759/cureus.22963 [doi] LID - e22963 AB - Carotid artery dissection is a significant cause of stroke in young patients. Here, we report a 33-year-old male who presented with right homonymous hemianopia and paresthesia of the right side of the body. Magnetic resonance imaging (MRI) of the brain revealed an acute infarct in the left parieto-occipital region. Magnetic resonance angiography (MRA) and duplex ultrasonography (USG) of the neck vessels suggested the left internal carotid artery dissection as the underlying cause. The patient was a known human leukocyte antigen (HLA) B27 and had a history of a previous attack of uveitis. This case report will raise awareness regarding the possible association of HLA B27 with the dissection of neck vessels. CI - Copyright (c) 2022, Huq et al. FAU - Huq, Muhammad Rezeul AU - Huq MR AD - Neurology, Combined Military Hospital, Dhaka, BGD. FAU - Kabir, Humayun AU - Kabir H AD - Neurology, Combined Military Hospital, Dhaka, BGD. FAU - Chowdhury, Md Ismail AU - Chowdhury MI AD - Neurology, Combined Military Hospital, Dhaka, BGD. FAU - Kawnayn, Ghulam AU - Kawnayn G AD - Neurology, Combined Military Hospital, Dhaka, BGD. LA - eng PT - Case Reports DEP - 20220308 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC8989624 OTO - NOTNLM OT - cervical artery dissection OT - hla b27 OT - hla b27 association OT - internal carotid artery dissection OT - young-onset stroke COIS- The authors have declared that no competing interests exist. EDAT- 2022/04/13 06:00 MHDA- 2022/04/13 06:01 PMCR- 2022/03/08 CRDT- 2022/04/12 05:31 PHST- 2022/03/08 00:00 [accepted] PHST- 2022/04/12 05:31 [entrez] PHST- 2022/04/13 06:00 [pubmed] PHST- 2022/04/13 06:01 [medline] PHST- 2022/03/08 00:00 [pmc-release] AID - 10.7759/cureus.22963 [doi] PST - epublish SO - Cureus. 2022 Mar 8;14(3):e22963. doi: 10.7759/cureus.22963. eCollection 2022 Mar.