PMID- 35414414
OWN - NLM
STAT- MEDLINE
DCOM- 20220628
LR  - 20220712
IS  - 1873-4898 (Electronic)
IS  - 1477-5131 (Linking)
VI  - 18
IP  - 3
DP  - 2022 Jun
TI  - Comparison of hypochlorous acid and Povidone Iodine as a disinfectant in neonatal 
      circumcision.
PG  - 341.e1-341.e5
LID - S1477-5131(22)00108-5 [pii]
LID - 10.1016/j.jpurol.2022.03.011 [doi]
AB  - INTRODUCTION: Neonatal circumcision is a procedure used worldwide which has very 
      low rates of complication if conducted by a specialist. The present research aims 
      to examine the wound healing effects of Hypochlorous Acid (HCOL) and Povidone 
      Iodine (PI) used as a disinfectant prior to the procedure of circumcision and 
      their antibacterial effectiveness. MATERIAL AND METHOD: The findings of sixty 
      infants subjected to neonatal circumcision at the Hisar Intercontinental Hospital 
      between January 2021 and June 2021 were prospectively recorded. Based on the 
      disinfectant used, the patients were divided into two group: Group 1 including 28 
      patients for whom HCOL was used as an antiseptic solution, and Group 2 including 
      32 patients to whom PI was administered. RESULTS: Group 1 was formed of 28 
      patients while Group 2 included 32 patients. The mean ages of each group was 
      15.46 +/- 10.58 (2-29) and 12.63 +/- 10.00 (2-28) days, respectively. When the 
      complications were examined individually, no significant difference was found 
      between the groups. However, when all complications were analyzed collectively, 
      it was determined that there was a significant difference, and the complication 
      rate of Group 2 was greater (p = 0.037). In Group 2, the rate of edema and wound 
      healing delay was significantly greater than that of Group 1 (p: 0.037 p: 0.036) 
      (Table 1). CONCLUSION: It was determined that HCOL is reliable to be used as a 
      disinfectant prior to neonatal circumcision.
CI  - Copyright (c) 2022 Journal of Pediatric Urology Company. Published by Elsevier Ltd. 
      All rights reserved.
FAU - Gozukucuk, Ali
AU  - Gozukucuk A
AD  - Department of Pediatric Surgery, Hisar Intercontinental Hospital, Dogus 
      University, Istanbul, Turkey. Electronic address: agozukucuk@dogus.edu.tr.
FAU - Cakiroglu, Basri
AU  - Cakiroglu B
AD  - Department of Urology, Hisar Intercontinental Hospital, Galata University, 
      Istanbul, Turkey. Electronic address: drbasri@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20220323
PL  - England
TA  - J Pediatr Urol
JT  - Journal of pediatric urology
JID - 101233150
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Infective Agents, Local)
RN  - 0 (Disinfectants)
RN  - 712K4CDC10 (Hypochlorous Acid)
RN  - 85H0HZU99M (Povidone-Iodine)
SB  - IM
MH  - Anti-Bacterial Agents/therapeutic use
MH  - *Anti-Infective Agents, Local
MH  - *Disinfectants
MH  - Humans
MH  - Hypochlorous Acid
MH  - Infant, Newborn
MH  - Male
MH  - Povidone-Iodine
OTO - NOTNLM
OT  - (HCOL)
OT  - Hypochlorous Acid
OT  - Neonatal circumcision
OT  - Povidone Iodine
EDAT- 2022/04/14 06:00
MHDA- 2022/06/29 06:00
CRDT- 2022/04/13 05:27
PHST- 2022/01/09 00:00 [received]
PHST- 2022/03/09 00:00 [revised]
PHST- 2022/03/11 00:00 [accepted]
PHST- 2022/04/14 06:00 [pubmed]
PHST- 2022/06/29 06:00 [medline]
PHST- 2022/04/13 05:27 [entrez]
AID - S1477-5131(22)00108-5 [pii]
AID - 10.1016/j.jpurol.2022.03.011 [doi]
PST - ppublish
SO  - J Pediatr Urol. 2022 Jun;18(3):341.e1-341.e5. doi: 10.1016/j.jpurol.2022.03.011. 
      Epub 2022 Mar 23.