PMID- 35417972
OWN - NLM
STAT- MEDLINE
DCOM- 20220415
LR  - 20220716
IS  - 0974-5181 (Electronic)
IS  - 0971-9784 (Print)
IS  - 0971-9784 (Linking)
VI  - 25
IP  - 2
DP  - 2022 Apr-Jun
TI  - Management of perioperative anticoagulation in a patient with antiphospholipid 
      antibody syndrome undergoing cardiac surgery: A case report.
PG  - 206-209
LID - 10.4103/aca.aca_228_20 [doi]
AB  - Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding 
      and thrombotic complications during cardiac surgery involving cardiopulmonary 
      bypass (CPB). In this case we present a patient with APLS and Immune 
      Thrombocytopenic Purpura who successfully underwent aortic valve replacement 
      (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. 
      Anticoagulation for CPB was monitored by targeting an Activated Clotting Time 
      (ACT) that was 2x the upper limit of normal. A multidisciplinary approach was 
      essential in ensuring a safe and successful operation.
FAU - Malviya, Sanjana A
AU  - Malviya SA
AD  - Baylor College of Medicine, Houston, Texas, USA.
FAU - Deng, Yi
AU  - Deng Y
AD  - Baylor College of Medicine, Houston, Texas, USA.
FAU - Gilani, Sayyed O
AU  - Gilani SO
AD  - Baylor College of Medicine, Houston, Texas, USA.
FAU - Hendon, Alec A
AU  - Hendon AA
AD  - Baylor College of Medicine, Houston, Texas, USA.
FAU - Nikolaidis, Melissa A
AU  - Nikolaidis MA
AD  - Baylor College of Medicine, Houston, Texas, USA.
FAU - Moseley, Micah S
AU  - Moseley MS
AD  - Baylor College of Medicine, Houston, Texas, USA.
LA  - eng
PT  - Case Reports
PL  - India
TA  - Ann Card Anaesth
JT  - Annals of cardiac anaesthesia
JID - 9815987
RN  - 0 (Anticoagulants)
SB  - IM
MH  - Anticoagulants/therapeutic use
MH  - *Antiphospholipid Syndrome/complications
MH  - Aortic Valve/surgery
MH  - Blood Coagulation
MH  - *Cardiac Surgical Procedures
MH  - Humans
PMC - PMC9244265
OTO - NOTNLM
OT  - Antifibrinolytics
OT  - Libman-Sacks endocarditis
OT  - antiphospholipid syndrome
OT  - cardiopulmonary bypass
OT  - immune thrombocytopenic purpura
COIS- There are no conflicts of interest.
EDAT- 2022/04/15 06:00
MHDA- 2022/04/16 06:00
PMCR- 2022/04/01
CRDT- 2022/04/14 04:00
PHST- 2022/04/14 04:00 [entrez]
PHST- 2022/04/15 06:00 [pubmed]
PHST- 2022/04/16 06:00 [medline]
PHST- 2022/04/01 00:00 [pmc-release]
AID - AnnCardAnaesth_2022_25_2_206_342839 [pii]
AID - ACA-25-206 [pii]
AID - 10.4103/aca.aca_228_20 [doi]
PST - ppublish
SO  - Ann Card Anaesth. 2022 Apr-Jun;25(2):206-209. doi: 10.4103/aca.aca_228_20.