PMID- 35420259
OWN - NLM
STAT- MEDLINE
DCOM- 20220609
LR  - 20220720
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 99
IP  - 7
DP  - 2022 Jun
TI  - Transcatheter closure of fenestrated atrial septal aneurysm in children: 
      Feasibility and long-term results.
PG  - 2043-2053
LID - 10.1002/ccd.30191 [doi]
AB  - BACKGROUND: To date, extensive experience in transcatheter closure of fenestrated 
      atrial septal aneurysm (ASA) in the pediatric population is limited. METHODS: To 
      report on procedural feasibility, efficacy, and long-term outcome, we enrolled 
      all children submitted to an attempt of transcatheter closure of fenestrated ASA 
      at two, large volume, pediatric cardiology units (Naples and Massa, Italy) 
      between April 2000 to May 2020. RESULTS: This retrospective study included 139 
      patients (median age 9 years [range 2-18] and weight 36 kg [range 10-102]); 19 
      (13.7%) children were </=20 kg (range 10-20) and 14 (10.1%) were </=5 years old. 
      Single perforation was observed in 28 patients (20.1%), while 111 patients 
      (79.9%) had multifenestrated ASA. The median size of the main defect was 15 mm 
      (range 6-34) and 25 patients (18%) had a defect >/=20 mm. The procedural success 
      rate was 99% (95% confidence interval [CI]: 94.9-99.8) using a single device in 
      75 (69%), two devices in 31 (28%), and three devices in 3 (3%) cases. Early minor 
      adverse events (AEs) occurred in four patients (2.8%). Late minor AEs were 
      recorded in one patient (0.7%) over a median follow-up of 5 years ([range 0-18 
      years; total 890.2 person-years, and with 30 patients (22%) followed >/=10 years). 
      Neither mortality nor major AEs were recorded. Freedom from AEs was 99.1% at 
      10-15 years (95% CI: 93.5-99.8%), without any difference according to atrial 
      septum anatomy or patient age and weight. CONCLUSION: Transcatheter closure of 
      fenestrated ASA is technically feasible and effective in children with excellent 
      long-term outcomes.
CI  - (c) 2022 Wiley Periodicals LLC.
FAU - Mahmoud, Heba Talat
AU  - Mahmoud HT
AUID- ORCID: 0000-0001-6171-5630
AD  - Pediatric Cardiology, University of Campania "Luigi Vanvitelli", "Ospedali dei 
      Colli", Naples, Italy.
AD  - Cardiology Department, Minia University, Minia, Egypt.
FAU - Gaio, Gianpiero
AU  - Gaio G
AD  - Pediatric Cardiology, University of Campania "Luigi Vanvitelli", "Ospedali dei 
      Colli", Naples, Italy.
FAU - Giordano, Mario
AU  - Giordano M
AUID- ORCID: 0000-0002-0583-5221
AD  - Pediatric Cardiology, University of Campania "Luigi Vanvitelli", "Ospedali dei 
      Colli", Naples, Italy.
FAU - Pizzuto, Alessandra
AU  - Pizzuto A
AD  - Pediatric Cardiology and GUCH Unit, Heart Hospital "G. Pasquinucci", National 
      Research Council-Tuscany Region Foundation "G. Monasterio", Massa, Italy.
FAU - Cuman, Madgalena
AU  - Cuman M
AD  - Pediatric Cardiology and GUCH Unit, Heart Hospital "G. Pasquinucci", National 
      Research Council-Tuscany Region Foundation "G. Monasterio", Massa, Italy.
FAU - Abdel Wahab, Mohammed Abdel Kader
AU  - Abdel Wahab MAK
AD  - Cardiology Department, Minia University, Minia, Egypt.
FAU - Palladino, Maria Teresa
AU  - Palladino MT
AD  - Pediatric Cardiology, University of Campania "Luigi Vanvitelli", "Ospedali dei 
      Colli", Naples, Italy.
FAU - Russo, Maria Giovanna
AU  - Russo MG
AD  - Pediatric Cardiology, University of Campania "Luigi Vanvitelli", "Ospedali dei 
      Colli", Naples, Italy.
FAU - Santoro, Giuseppe
AU  - Santoro G
AUID- ORCID: 0000-0001-6071-6973
AD  - Pediatric Cardiology, University of Campania "Luigi Vanvitelli", "Ospedali dei 
      Colli", Naples, Italy.
AD  - Pediatric Cardiology and GUCH Unit, Heart Hospital "G. Pasquinucci", National 
      Research Council-Tuscany Region Foundation "G. Monasterio", Massa, Italy.
LA  - eng
PT  - Journal Article
DEP - 20220414
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Adolescent
MH  - Cardiac Catheterization
MH  - Child
MH  - Child, Preschool
MH  - Feasibility Studies
MH  - *Heart Aneurysm/etiology
MH  - *Heart Septal Defects, Atrial
MH  - Humans
MH  - Retrospective Studies
MH  - *Septal Occluder Device
MH  - Treatment Outcome
OTO - NOTNLM
OT  - atrial septal aneurysm
OT  - atrial septal defect
OT  - long term
OT  - multifenestrated
OT  - pediatric
OT  - percutaneous
EDAT- 2022/04/15 06:00
MHDA- 2022/06/10 06:00
CRDT- 2022/04/14 08:38
PHST- 2022/02/17 00:00 [revised]
PHST- 2021/07/23 00:00 [received]
PHST- 2022/03/23 00:00 [accepted]
PHST- 2022/04/15 06:00 [pubmed]
PHST- 2022/06/10 06:00 [medline]
PHST- 2022/04/14 08:38 [entrez]
AID - 10.1002/ccd.30191 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2022 Jun;99(7):2043-2053. doi: 10.1002/ccd.30191. 
      Epub 2022 Apr 14.