PMID- 35429736
OWN - NLM
STAT- MEDLINE
DCOM- 20220602
LR  - 20220602
IS  - 1873-4367 (Electronic)
IS  - 0927-7765 (Linking)
VI  - 215
DP  - 2022 Jul
TI  - Cell membrane-based biomimetic nanosystems for advanced drug delivery in cancer 
      therapy: A comprehensive review.
PG  - 112503
LID - S0927-7765(22)00186-2 [pii]
LID - 10.1016/j.colsurfb.2022.112503 [doi]
AB  - Natural types of cells display distinct characteristics with homotypic targeting 
      and extended circulation in the blood, which are worthy of being explored as 
      promising drug delivery systems (DDSs) for cancer therapy. To enhance their 
      delivery efficiency, these cells can be combined with therapeutic agents and 
      artificial nanocarriers to construct the next generation of DDSs in the form of 
      biomimetic nanomedicines. In this review, we present the recent advances in cell 
      membrane-based DDSs (CDDSs) and their applications for efficient cancer therapy. 
      Different sources of cell membranes are discussed, mainly including red blood 
      cells (RBC), leukocytes, cancer cells, stem cells and hybrid cells. Moreover, the 
      extraction methods used for obtaining such cells and the mechanism contributing 
      to the functional action of these biomimetic CDDSs are explained. Finally, a 
      future perspective is proposed to highlight the limitations of CDDSs and the 
      possible resolutions toward clinical transformation of currently developed 
      biomimetic chemotherapies.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Zhao, Jianing
AU  - Zhao J
AD  - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of 
      Education of China), School of Pharmacy, Yantai University, Yantai 264005, China.
FAU - Ruan, Jian
AU  - Ruan J
AD  - Yantai Center for Food and Drug Control, Yantai 264005, China.
FAU - Lv, Guangyao
AU  - Lv G
AD  - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of 
      Education of China), School of Pharmacy, Yantai University, Yantai 264005, China.
FAU - Shan, Qi
AU  - Shan Q
AD  - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of 
      Education of China), School of Pharmacy, Yantai University, Yantai 264005, China.
FAU - Fan, Zhiping
AU  - Fan Z
AD  - Institute of BioPharmaceutical Research, Liaocheng University, Liaocheng 252059, 
      China.
FAU - Wang, Hongbo
AU  - Wang H
AD  - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of 
      Education of China), School of Pharmacy, Yantai University, Yantai 264005, China. 
      Electronic address: hongbowangyt@163.com.
FAU - Du, Yuan
AU  - Du Y
AD  - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of 
      Education of China), School of Pharmacy, Yantai University, Yantai 264005, China. 
      Electronic address: duyuan@ytu.edu.cn.
FAU - Ling, Longbing
AU  - Ling L
AD  - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Ministry of 
      Education of China), School of Pharmacy, Yantai University, Yantai 264005, China. 
      Electronic address: linglongbing@ytu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220411
PL  - Netherlands
TA  - Colloids Surf B Biointerfaces
JT  - Colloids and surfaces. B, Biointerfaces
JID - 9315133
SB  - IM
MH  - *Biomimetic Materials
MH  - Biomimetics
MH  - Cell Membrane
MH  - Drug Delivery Systems
MH  - Nanomedicine
MH  - *Nanoparticles
MH  - *Neoplasms/drug therapy
OTO - NOTNLM
OT  - Biomimetic
OT  - Cancer therapy
OT  - Cell membrane
OT  - Drug delivery systems
OT  - Nanoparticles
EDAT- 2022/04/17 06:00
MHDA- 2022/06/03 06:00
CRDT- 2022/04/16 20:10
PHST- 2021/12/23 00:00 [received]
PHST- 2022/03/08 00:00 [revised]
PHST- 2022/04/08 00:00 [accepted]
PHST- 2022/04/17 06:00 [pubmed]
PHST- 2022/06/03 06:00 [medline]
PHST- 2022/04/16 20:10 [entrez]
AID - S0927-7765(22)00186-2 [pii]
AID - 10.1016/j.colsurfb.2022.112503 [doi]
PST - ppublish
SO  - Colloids Surf B Biointerfaces. 2022 Jul;215:112503. doi: 
      10.1016/j.colsurfb.2022.112503. Epub 2022 Apr 11.