PMID- 35430168
OWN - NLM
STAT- MEDLINE
DCOM- 20220706
LR  - 20220802
IS  - 2095-4964 (Print)
VI  - 20
IP  - 4
DP  - 2022 Jul
TI  - Remission of type 2 diabetes depends on prompt comprehensive lifestyle changes 
      upon diagnosis: How can this "Road to Damascus" experience be supported?
PG  - 288-291
LID - S2095-4964(22)00047-4 [pii]
LID - 10.1016/j.joim.2022.04.001 [doi]
AB  - Theoretically, a new diagnosis of type 2 diabetes mellitus (T2DM) requires a 
      dramatic change in an individual's way of life. Weight loss and physical activity 
      can lead to remission of diabetes, which has been associated with a lower risk of 
      developing complications. Today, the importance of a healthy lifestyle is further 
      highlighted by data showing that obesity and diabetes increase the risk of severe 
      complications from coronavirus disease 2019. However, remission rarely occurs in 
      reality, probably due to the inability of people with T2DM to adhere to the 
      intensive lifestyle interventions that are necessary. The complexity of 
      contributing factors may explain why making these changes is so challenging and 
      underscore the fact that there is no magical solution for T2DM. Instead, hard 
      work from both patients and health care providers is needed for the conversion to 
      be achieved. This article calls for more research on the underlying reasons why 
      adhering to a healthy way of life is so difficult for people with diabetes and 
      obesity. Clearly defining these barriers would facilitate the planning of 
      effective policies to promote the adoption of appropriate lifestyle changes early 
      in the course of the disease.
CI  - Copyright (c) 2022 Shanghai Changhai Hospital. Published by Elsevier B.V. All 
      rights reserved.
FAU - Koufakis, Theocharis
AU  - Koufakis T
AD  - Division of Endocrinology and Metabolism and Diabetes Centre, First Department of 
      Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA 
      University Hospital, 54636 Thessaloniki, Greece.
FAU - Kotsa, Kalliopi
AU  - Kotsa K
AD  - Division of Endocrinology and Metabolism and Diabetes Centre, First Department of 
      Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA 
      University Hospital, 54636 Thessaloniki, Greece.
FAU - Papanas, Nikolaos
AU  - Papanas N
AD  - Diabetes Centre, Second Department of Internal Medicine, Democritus University of 
      Thrace, 68100 Alexandroupolis, Greece. Electronic address: papanasnikos@yahoo.gr.
LA  - eng
PT  - Journal Article
DEP - 20220408
PL  - Netherlands
TA  - J Integr Med
JT  - Journal of integrative medicine
JID - 101603118
SB  - IM
MH  - *COVID-19
MH  - *Diabetes Mellitus, Type 2/diagnosis/therapy
MH  - Exercise
MH  - Humans
MH  - Life Style
MH  - Obesity/therapy
OTO - NOTNLM
OT  - Diet
OT  - Exercise
OT  - Lifestyle change
OT  - Remission
OT  - Type 2 diabetes
COIS- Declaration of competing interest TK has received honoraria as a speaker from 
      AstraZeneca, Boehringer Ingelheim, Pharmaserve Lilly and Novo Nordisk and has 
      participated in sponsored studies by Eli-Lilly. KK has received honoraria for 
      lectures/advisory boards and research support from AstraZeneca, Boehringer 
      Ingelheim, Pharmaserve Lilly, Sanofi-Aventis, ELPEN, MSD, and Novo Nordisk. NP 
      has been an advisory board member of AstraZeneca, Boehringer Ingelheim, MSD, Novo 
      Nordisk, Pfizer, Takeda and TrigoCare International; has participated in 
      sponsored studies by Astra-Zeneca, Eli-Lilly, GSK, MSD, Novo Nordisk, Novartis 
      and Sanofi-Aventis; has received honoraria as a speaker for AstraZeneca, 
      Boehringer Ingelheim, Eli-Lilly, Elpen, MSD, Mylan, Novo Nordisk, Pfizer, 
      Sanofi-Aventis and Vianex; and attended conferences sponsored by TrigoCare 
      International, Eli-Lilly, Galenica, Novo Nordisk, Pfizer and Sanofi-Aventis.
EDAT- 2022/04/18 06:00
MHDA- 2022/07/07 06:00
CRDT- 2022/04/17 20:17
PHST- 2021/12/03 00:00 [received]
PHST- 2022/03/01 00:00 [accepted]
PHST- 2022/04/18 06:00 [pubmed]
PHST- 2022/07/07 06:00 [medline]
PHST- 2022/04/17 20:17 [entrez]
AID - S2095-4964(22)00047-4 [pii]
AID - 10.1016/j.joim.2022.04.001 [doi]
PST - ppublish
SO  - J Integr Med. 2022 Jul;20(4):288-291. doi: 10.1016/j.joim.2022.04.001. Epub 2022 
      Apr 8.