PMID- 35435983 OWN - NLM STAT- MEDLINE DCOM- 20220602 LR - 20220602 IS - 2042-7174 (Electronic) IS - 0961-7671 (Linking) VI - 30 IP - 2 DP - 2022 May 26 TI - Interventions developed to reduce secondary care utilisation in patients with type 2 diabetes mellitus: a narrative review. PG - 116-128 LID - 10.1093/ijpp/riac009 [doi] AB - OBJECTIVES: To identify, describe and critically appraise the quality of studies of interventions developed to reduce the rate of secondary care utilisation and investigate interventions' impact on patients with type 2 diabetes mellitus (T2DM). METHOD: Using a systematic approach, five databases were searched between 01 January 1995 and 01 February 2021 (MEDLINE, EMBASE, PsycINFO, CINAHL and Cochrane database). Inclusion criteria were studies (published in English) in adults with T2DM offered intervention(s) involving medicines/services/educational programmes in any country or setting, with investigated outcomes including the rate of hospital admission/re-admission/accident and emergency visits. Validated tools were used to assess the quality and accuracy of reporting the interventions. A narrative synthesis was used to frame the findings. KEY FINDINGS: A total of 4670 papers were identified, which yielded a final 53 studies after screening against the inclusion criteria. Identified interventions were complex interventions (n = 21) including at least two interventions (e.g. improving medication adherence and patient education), medication management (n = 15), patient education programmes (n = 8), lifestyle interventions (n = 5) and other interventions (n = 4; e.g. dental care). After assessing for quality and effectiveness of interventions, 15 studies remained; 7 were medication management interventions (e.g. use of insulin pen) and 8 were complex interventions (e.g. pharmaceutical care and telehealth systems). Complex interventions showed significant improvement in clinical outcomes and reduction in secondary care utilisation. CONCLUSIONS: This narrative review identified potential elements of an effective complex intervention to reduce healthcare utilisation in patients with T2DM. These results could inform the development of interventions to be tested for feasibility, before piloting to assess for outcomes that improve diabetic care, reduce diabetes-related complications and minimise healthcare utilisation. CI - (c) The Author(s) 2022. Published by Oxford University Press on behalf of the Royal Pharmaceutical Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. FAU - Khayyat, Sarah M AU - Khayyat SM AUID- ORCID: 0000-0002-0316-1825 AD - Department of Clinical Pharmacy, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia. AD - School of Pharmacy, Newcastle University, Newcastle upon Tyne, UK. FAU - Walters, Philippa A AU - Walters PA AD - School of Pharmacy, Newcastle University, Newcastle upon Tyne, UK. FAU - Whittlesea, Cate AU - Whittlesea C AD - UCL School of Pharmacy, University College of London, London, UK. FAU - Nazar, Hamde AU - Nazar H AUID- ORCID: 0000-0002-3168-5386 AD - School of Pharmacy, Newcastle University, Newcastle upon Tyne, UK. LA - eng PT - Journal Article PT - Review PL - England TA - Int J Pharm Pract JT - The International journal of pharmacy practice JID - 9204243 SB - IM MH - Adult MH - *Diabetes Mellitus, Type 2/therapy MH - Humans MH - Medication Adherence MH - Patient Acceptance of Health Care MH - Secondary Care OTO - NOTNLM OT - accident and emergency visit OT - hospital admission OT - hospital re-admission OT - secondary care utilisation OT - type 2 diabetes mellitus EDAT- 2022/04/19 06:00 MHDA- 2022/06/03 06:00 CRDT- 2022/04/18 12:12 PHST- 2021/05/26 00:00 [received] PHST- 2022/02/02 00:00 [accepted] PHST- 2022/04/19 06:00 [pubmed] PHST- 2022/06/03 06:00 [medline] PHST- 2022/04/18 12:12 [entrez] AID - 6569883 [pii] AID - 10.1093/ijpp/riac009 [doi] PST - ppublish SO - Int J Pharm Pract. 2022 May 26;30(2):116-128. doi: 10.1093/ijpp/riac009.