PMID- 35440219
OWN - NLM
STAT- Publisher
LR  - 20240220
IS  - 1942-7522 (Electronic)
IS  - 0145-5613 (Linking)
DP  - 2022 Apr 19
TI  - Association between Clinical Factors and Surgical Outcomes for Patients with 
      Persistent Allergic Rhinitis.
PG  - 1455613221091098
LID - 10.1177/01455613221091098 [doi]
AB  - Objective: While septoplasty with turbinoplasty is commonly performed for 
      patients with nasal obstruction, no study has addressed its efficacy and related 
      determinants in patients with allergic rhinitis (AR) and various symptoms. This 
      study aimed to identify potential factors associated with surgical outcomes in 
      patients with persistent AR (PAR) who underwent septoplasty with turbinoplasty. 
      Methods: We prospectively recruited patients with PAR and positive allergy test 
      results for surgical treatment. We also collected relevant preoperative 
      laboratory data. The Sinonasal Outcome Test-22 (SNOT-22) survey was administered 
      to all patients one day before and one year after surgery. Results: A total of 
      128 patients who completed a one-year postoperative follow-up were enrolled. The 
      total SNOT-22 score and five subdomain scores significantly improved 
      postoperatively. We found that women and those with higher preoperative SNOT-22 
      scores experienced more postoperative improvement and had a greater potential to 
      reach minimal clinically important differences (MCID). A preoperative SNOT-22 
      score greater than the determined cut-off value of 42.5 had an approximately 
      6-fold likelihood of MCID achievement. Patients in the nasal obstruction group 
      and non-smokers demonstrated greater postoperative improvement in the sleep 
      subdomain. Conclusions: Women with PAR and those with a preoperative SNOT-22 
      score above 42.5 were preferable candidates for surgery and expressed greater 
      satisfaction. Notably, rhinologic presentations and non-rhinologic symptoms of 
      PAR patients could benefit from within one year after surgery. Here, we discuss 
      the factors associated with subjective surgical outcomes to help physicians and 
      patients with AR in preoperative consultations.
FAU - Ho, Yan-Ting
AU  - Ho YT
AD  - Department of Otolaryngology, Head and Neck Surgery, 38014Chang Gung Memorial 
      Hospital and Chang Gung University, Taoyuan, Taiwan.
FAU - Lee, Ta-Jen
AU  - Lee TJ
AUID- ORCID: 0000-0003-0508-1359
AD  - Department of Otolaryngology, Head and Neck Surgery, 38014Chang Gung Memorial 
      Hospital and Chang Gung University, Taoyuan, Taiwan.
FAU - Fu, Chia-Hsiang
AU  - Fu CH
AD  - Department of Otolaryngology, Head and Neck Surgery, 38014Chang Gung Memorial 
      Hospital and Chang Gung University, Taoyuan, Taiwan.
AD  - Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung 
      University, Taoyuan, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20220419
PL  - United States
TA  - Ear Nose Throat J
JT  - Ear, nose, & throat journal
JID - 7701817
SB  - IM
OTO - NOTNLM
OT  - Sinonasal Outcome Test-22 (SNOT-22)
OT  - allergic rhinitis
OT  - minimal clinically important difference (MCID)
OT  - nasal obstruction
OT  - quality of life
OT  - surgery
EDAT- 2022/04/21 06:00
MHDA- 2022/04/21 06:00
CRDT- 2022/04/20 05:21
PHST- 2022/04/20 05:21 [entrez]
PHST- 2022/04/21 06:00 [pubmed]
PHST- 2022/04/21 06:00 [medline]
AID - 10.1177/01455613221091098 [doi]
PST - aheadofprint
SO  - Ear Nose Throat J. 2022 Apr 19:1455613221091098. doi: 10.1177/01455613221091098.