PMID- 35441839
OWN - NLM
STAT- MEDLINE
DCOM- 20221118
LR  - 20230102
IS  - 1432-1084 (Electronic)
IS  - 0938-7994 (Print)
IS  - 0938-7994 (Linking)
VI  - 32
IP  - 11
DP  - 2022 Nov
TI  - Image quality comparison of single-energy and dual-energy computed tomography for 
      head and neck patients: a prospective randomized study.
PG  - 7700-7709
LID - 10.1007/s00330-022-08689-4 [doi]
AB  - OBJECTIVES: The aim of this study was to compare the quality of images obtained 
      using single-energy computed tomography (SECT) performed with automated tube 
      voltage adaptation (TVA) with dual-energy CT (DECT) weighted average images. 
      METHODS: Eighty patients were prospectively randomized to undergo either SECT 
      with TVA (n = 40, ref. mAs 200) or radiation dose-matched DECT (n = 40, 80/Sn150 
      kV, ref. mAs tube A 91/tube B 61) on a dual-source CT scanner. Objective image 
      quality was evaluated as dose-normalized contrast-to-noise ratio (CNRD) for the 
      jugular veins relative to fatty tissue and muscle tissue and for muscle tissue 
      relative to fatty issue. For subjective image quality, reproduction of anatomical 
      structures, image artifacts, image noise, spatial resolution, and overall 
      diagnostic acceptability were evaluated at sixteen anatomical substructures using 
      Likert-type scales. RESULTS: Effective radiation dose (ED) was comparable between 
      SECT and DECT study groups (2.9 +/- 0.6 mSv/3.1 +/- 0.7 mSv, p = 0.5). All 
      examinations were rated as excellent or good for clinical diagnosis. Compared to 
      the CNRD in the SECT group, the CNRD in the DECT group was significantly higher 
      for the jugular veins relative to fatty tissue (7.51/6.08, p < 0.001) and for 
      muscle tissue relative to fatty tissue (4.18/2.90, p < 0.001). The CNRD for the 
      jugular veins relative to muscle tissue (3.33/3.18, p = 0.51) was comparable 
      between groups. Image artifacts were less pronounced and overall diagnostic 
      acceptability was higher in the DECT group (all p = 0.01). CONCLUSIONS: DECT 
      weighted average images deliver higher objective and subjective image quality 
      than SECT performed with TVA in head and neck imaging. KEY POINTS: * Weighted 
      average images derived from dual-energy CT deliver higher objective and 
      subjective image quality than single-energy CT using automated tube voltage 
      adaptation in head and neck imaging. * If available, dual-energy CT acquisition 
      may be preferred over automated low tube voltage adopted single-energy CT for 
      both malignant and non-malignant conditions.
CI  - (c) 2022. The Author(s).
FAU - Bedernik, Andreas
AU  - Bedernik A
AD  - Institute of Radiology, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Maximiliansplatz 3, 
      91054, Erlangen, Germany.
FAU - Wuest, Wolfgang
AU  - Wuest W
AD  - Institute of Radiology, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Maximiliansplatz 3, 
      91054, Erlangen, Germany.
AD  - Imaging Science Institute, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Erlangen, Germany.
FAU - May, Matthias Stefan
AU  - May MS
AD  - Institute of Radiology, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Maximiliansplatz 3, 
      91054, Erlangen, Germany.
AD  - Imaging Science Institute, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Erlangen, Germany.
FAU - Heiss, Rafael
AU  - Heiss R
AD  - Institute of Radiology, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Maximiliansplatz 3, 
      91054, Erlangen, Germany.
AD  - Imaging Science Institute, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Erlangen, Germany.
FAU - Uder, Michael
AU  - Uder M
AD  - Institute of Radiology, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Maximiliansplatz 3, 
      91054, Erlangen, Germany.
AD  - Imaging Science Institute, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Erlangen, Germany.
FAU - Wiesmueller, Marco
AU  - Wiesmueller M
AUID- ORCID: 0000-0002-4185-1122
AD  - Institute of Radiology, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Maximiliansplatz 3, 
      91054, Erlangen, Germany. marco.wiesmueller@uk-erlangen.de.
AD  - Imaging Science Institute, University Hospital Erlangen, 
      Friedrich-Alexander-Universitat Erlangen-Nurnberg (FAU), Erlangen, Germany. 
      marco.wiesmueller@uk-erlangen.de.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20220420
PL  - Germany
TA  - Eur Radiol
JT  - European radiology
JID - 9114774
SB  - IM
MH  - Humans
MH  - Radiation Dosage
MH  - Prospective Studies
MH  - *Tomography, X-Ray Computed/methods
MH  - *Head/diagnostic imaging
MH  - Neck
PMC - PMC9668949
OTO - NOTNLM
OT  - Automated tube voltage adaptation
OT  - Dual-energy computed tomography
OT  - Head and neck imaging
OT  - Weighted average dual-energy images
COIS- The authors of this manuscript declare no relationships with any companies whose 
      products or services may be related to the subject matter of the article.
EDAT- 2022/04/21 06:00
MHDA- 2022/11/19 06:00
PMCR- 2022/04/20
CRDT- 2022/04/20 12:01
PHST- 2021/10/12 00:00 [received]
PHST- 2022/02/22 00:00 [accepted]
PHST- 2022/02/15 00:00 [revised]
PHST- 2022/04/21 06:00 [pubmed]
PHST- 2022/11/19 06:00 [medline]
PHST- 2022/04/20 12:01 [entrez]
PHST- 2022/04/20 00:00 [pmc-release]
AID - 10.1007/s00330-022-08689-4 [pii]
AID - 8689 [pii]
AID - 10.1007/s00330-022-08689-4 [doi]
PST - ppublish
SO  - Eur Radiol. 2022 Nov;32(11):7700-7709. doi: 10.1007/s00330-022-08689-4. Epub 2022 
      Apr 20.