PMID- 35442330
OWN - NLM
STAT- MEDLINE
DCOM- 20220422
LR  - 20220422
IS  - 1678-4219 (Electronic)
IS  - 0004-2803 (Linking)
VI  - 59
IP  - 1
DP  - 2022 Jan-Mar
TI  - SMALL AS WELL AS LARGE COLORECTAL LESIONS ARE EFFECTIVELY MANAGED BY ENDOSCOPIC 
      MUCOSAL RESECTION TECHNIQUE.
PG  - 16-21
LID - S0004-28032022000100016 [pii]
LID - 10.1590/S0004-2803.202200001-04 [doi]
AB  - BACKGROUND: Endoscopic mucosal resection (EMR) is an easy-to-use treatment option 
      for superficial colorectal lesions, including lesions >/=20 mm. OBJECTIVE: To 
      evaluate the effectiveness of EMR. METHODS: We evaluated 430 lesions removed by 
      EMR in 404 patients. The lesions were analyzed according to their morphology, 
      size, location, and histology. Lesions <20 mm were resected en bloc, whereas 
      lesions >/=20 mm were removed by piecemeal EMR (p-EMR). Adverse events and 
      recurrence were assessed. RESULTS: Regarding morphology, 145 (33.7%) were 
      depressed lesions, 157 (36.5%) were polypoid lesions and 128 (29.8%) were 
      laterally spreading lesions, with 361 (84%) lesions <20 mm and 69 (16%) >/=20 mm. 
      Regarding histology, 413 (96%) lesions were classified as neoplastic lesions. 
      Overall, 14 (3.3%) adverse reactions occurred, most commonly in lesions removed 
      by p-EMR (P<0.001) and associated with advanced histology (P=0.008). Recurrence 
      occurred in 14 (5.2%) cases, more commonly in lesions removed by p-EMR (P<0.001). 
      CONCLUSION: EMR is an effective technique for the treatment of superficial 
      colorectal lesions, even of large lesions.
FAU - Santos, Carlos Eduardo Oliveira Dos
AU  - Santos CEOD
AUID- ORCID: 0000-0003-4333-3182
AD  - Hospital Santa Casa de Caridade, Departamento de Endoscopia, Bage, RS, Brasil.
AD  - Pontificia Universidade Catolica do Rio Grande do Sul, Departamento de 
      Endoscopia, Porto Alegre, RS, Brasil.
FAU - Nader, Lysandro Alsina
AU  - Nader LA
AUID- ORCID: 0000-0003-4383-7401
AD  - Universidade Federal de Pelotas, Unidade de Endoscopia, Pelotas, RS, Brasil.
FAU - Scherer, Cintia
AU  - Scherer C
AUID- ORCID: 0000-0001-9259-3349
AD  - Universidade Federal de Pelotas, Unidade de Endoscopia, Pelotas, RS, Brasil.
FAU - Furlan, Rafaelle Gaglioto
AU  - Furlan RG
AUID- ORCID: 0000-0002-0349-3600
AD  - Hospital Santa Casa de Caridade, Departamento de Endoscopia, Bage, RS, Brasil.
FAU - Sanmartin, Ivan David Arciniegas
AU  - Sanmartin IDA
AUID- ORCID: 0000-0003-2074-5221
AD  - Hospital Mae de Deus, Departamento de Gastroenterologia e Endoscopia, Porto 
      Alegre, RS, Brasil.
FAU - Pereira-Lima, Julio Carlos
AU  - Pereira-Lima JC
AUID- ORCID: 0000-0002-6070-6916
AD  - Santa Casa Hospital, Departamento de Gastroenterologia e Endoscopia, Porto 
      Alegre, RS, Brasil.
LA  - eng
PT  - Journal Article
PL  - Brazil
TA  - Arq Gastroenterol
JT  - Arquivos de gastroenterologia
JID - 15310600R
SB  - IM
MH  - Colonoscopy
MH  - *Colorectal Neoplasms/pathology/surgery
MH  - *Endoscopic Mucosal Resection/methods
MH  - Humans
MH  - Intestinal Mucosa/pathology/surgery
MH  - Treatment Outcome
EDAT- 2022/04/21 06:00
MHDA- 2022/04/23 06:00
CRDT- 2022/04/20 12:15
PHST- 2021/04/06 00:00 [received]
PHST- 2021/08/06 00:00 [accepted]
PHST- 2022/04/20 12:15 [entrez]
PHST- 2022/04/21 06:00 [pubmed]
PHST- 2022/04/23 06:00 [medline]
AID - S0004-28032022000100016 [pii]
AID - 10.1590/S0004-2803.202200001-04 [doi]
PST - ppublish
SO  - Arq Gastroenterol. 2022 Jan-Mar;59(1):16-21. doi: 
      10.1590/S0004-2803.202200001-04.