PMID- 35449225
OWN - NLM
STAT- MEDLINE
DCOM- 20220425
LR  - 20220716
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 12
IP  - 1
DP  - 2022 Apr 21
TI  - Effects of nanosized water droplet generation on number concentration measurement 
      of virus aerosols when using an airblast atomizer.
PG  - 6546
LID - 10.1038/s41598-022-10440-4 [doi]
LID - 6546
AB  - Development of efficient virus aerosol monitoring and removal devices requires 
      aerosolization of the test virus using atomizers. The number concentration and 
      size measurements of aerosolized virus particles are required to evaluate the 
      performance of the devices. Although diffusion dryers can remove water droplets 
      generated using atomizers, they often fail to remove them entirely from the air 
      stream. Consequently, particle measurement devices, such as scanning mobility 
      particle sizer (SMPS), can falsely identify the remaining nanosized water 
      droplets as virus aerosol particles. This in turn affects the accuracy of the 
      evaluation of devices for sampling or removing virus aerosol particles. In this 
      study, a plaque-forming assay combined with SMPS measurement was used to evaluate 
      sufficient drying conditions. We proposed an empirical equation to determine the 
      total number concentration of aerosolized particles measured using the SMPS as a 
      function of the carrier air flow rate and residence time of the particles in the 
      diffusion dryers. The difference in the total number concentration of particles 
      under sufficient and insufficient diffusion drying conditions was presented as a 
      percentage of error.
CI  - (c) 2022. The Author(s).
FAU - Massoudifarid, Milad
AU  - Massoudifarid M
AUID- ORCID: 0000-0002-1223-5478
AD  - Department of Mechanical Engineering, Yonsei University, Seoul, 03722, Republic 
      of Korea.
FAU - Piri, Amin
AU  - Piri A
AUID- ORCID: 0000-0002-7716-4308
AD  - Department of Mechanical Engineering, Yonsei University, Seoul, 03722, Republic 
      of Korea.
FAU - Hwang, Jungho
AU  - Hwang J
AUID- ORCID: 0000-0002-0304-7360
AD  - Department of Mechanical Engineering, Yonsei University, Seoul, 03722, Republic 
      of Korea. hwangjh@yonsei.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220421
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - 0 (Aerosols)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Aerosols/analysis
MH  - *Environmental Monitoring
MH  - Nebulizers and Vaporizers
MH  - Particle Size
MH  - *Water
PMC - PMC9022418
COIS- The authors declare no competing interests.
EDAT- 2022/04/23 06:00
MHDA- 2022/04/26 06:00
PMCR- 2022/04/21
CRDT- 2022/04/22 05:45
PHST- 2021/10/05 00:00 [received]
PHST- 2022/03/30 00:00 [accepted]
PHST- 2022/04/22 05:45 [entrez]
PHST- 2022/04/23 06:00 [pubmed]
PHST- 2022/04/26 06:00 [medline]
PHST- 2022/04/21 00:00 [pmc-release]
AID - 10.1038/s41598-022-10440-4 [pii]
AID - 10440 [pii]
AID - 10.1038/s41598-022-10440-4 [doi]
PST - epublish
SO  - Sci Rep. 2022 Apr 21;12(1):6546. doi: 10.1038/s41598-022-10440-4.