PMID- 35451389
OWN - NLM
STAT- MEDLINE
DCOM- 20220425
LR  - 20230103
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 101
IP  - 10
DP  - 2022 Mar 11
TI  - Effectiveness of intervention for aromatase inhibitor-associated musculoskeletal 
      symptoms: A protocol for systematic review and meta-analysis.
PG  - e28982
LID - 10.1097/MD.0000000000028982 [doi]
LID - e28982
AB  - BACKGROUND: Aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) are 
      among the most common prominent side effects in patients using aromatase 
      inhibitors (AIs) for breast cancer. Muscle and joint pain, morning stiffness, 
      arthritis, and bone loss are common clinical symptoms in individuals. Traditional 
      Chinese medicine (TCM) has been demonstrated to be useful in the treatment of 
      AIMSS in previous investigations, although the sample sizes were limited, and 
      systematic reviews were inadequate. The effectiveness and safety of TCM in the 
      treatment of AIMSS will be investigated in this study. METHODS: Randomized 
      controlled trials from January 2010 to October 2021 were limited to English or 
      Chinese. We searched PubMed, EMBASE, Cochrane Library, Web of Science, Medline, 
      China Biomedical Database (CBM), China National Knowledge Infrastructure (CNKI), 
      Wanfang database, and the VIP database. Two researchers reviewed the literature 
      and retrieved the data independently. Review Manager V5.3.was used to conduct the 
      statistical analysis. RESULTS: This systematic review and meta-analysis presents 
      the most recent data on the use of TCM to treat AIMSS and offers a scientifically 
      sound foundation for therapeutic practice. Upon completion, the findings will be 
      submitted to a peer-reviewed journal. ETHICS AND DISSEMINATION: As the systematic 
      review protocol did not involve human subjects, ethical approval was not 
      required. PROSPERO REGISTRATION NUMBER: CRD42020192553.
CI  - Copyright (c) 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Meng, Hui
AU  - Meng H
AD  - Beijing University of Chinese Medicine, North of the Third Ring, Chaoyang 
      District, Beijing, PR China.
AD  - Beijing Traditional Chinese Medicine Hospital, Capital Medical University, 
      Dongcheng District, Beijing, PR China.
FAU - Chen, Yuhan
AU  - Chen Y
AD  - Beijing University of Chinese Medicine, North of the Third Ring, Chaoyang 
      District, Beijing, PR China.
AD  - Beijing Traditional Chinese Medicine Hospital, Capital Medical University, 
      Dongcheng District, Beijing, PR China.
FAU - Yu, Mingwei
AU  - Yu M
AD  - Beijing Traditional Chinese Medicine Hospital, Capital Medical University, 
      Dongcheng District, Beijing, PR China.
FAU - Wang, Xiaomin
AU  - Wang X
AUID- ORCID: 0000-0003-1274-224
AD  - Beijing Traditional Chinese Medicine Hospital, Capital Medical University, 
      Dongcheng District, Beijing, PR China.
LA  - eng
GR  - 7202065/Natural Science Foundation of Beijing Municipality/
GR  - Z191100008319006/Beijing Science and Technology Planning Project/
PT  - Journal Article
DEP - 20220311
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Aromatase Inhibitors)
SB  - IM
MH  - *Aromatase Inhibitors/adverse effects
MH  - Humans
MH  - *Medicine, Chinese Traditional/methods
MH  - Meta-Analysis as Topic
MH  - Research Design
MH  - Systematic Reviews as Topic
PMC - PMC8913103
COIS- The authors report no conflicts of interest. Declaration of Competing Interest: 
      Yu Mingwei (e-mail: yumingwei@ccmu.edu.cn) and Wang Xiaomin (e-mail: 
      wangxiaomin_bhtcm@126.com) contributed equally to this article as 
      co-corresponding authors. All authors have no conflicts of interest.
EDAT- 2022/04/23 06:00
MHDA- 2022/04/26 06:00
PMCR- 2022/03/11
CRDT- 2022/04/22 08:38
PHST- 2022/02/10 00:00 [received]
PHST- 2022/02/14 00:00 [accepted]
PHST- 2022/04/22 08:38 [entrez]
PHST- 2022/04/23 06:00 [pubmed]
PHST- 2022/04/26 06:00 [medline]
PHST- 2022/03/11 00:00 [pmc-release]
AID - 00005792-202203110-00014 [pii]
AID - MD-D-22-00704 [pii]
AID - 10.1097/MD.0000000000028982 [doi]
PST - epublish
SO  - Medicine (Baltimore). 2022 Mar 11;101(10):e28982. doi: 
      10.1097/MD.0000000000028982.