PMID- 3545703 OWN - NLM STAT- MEDLINE DCOM- 19870415 LR - 20150901 IS - 0253-2662 (Print) IS - 0253-2662 (Linking) VI - 19 IP - 3 DP - 1986 Aug TI - Serum levels of beta-2 microglobulin in oral tumor patients. PG - 183-8 AB - Beta-2 microglobulin (beta-MG) is a low molecular weight protein of 100 amino-acids. It is the light chain of HLA-A, -B or -C antigens which on the surface of nearly all nucleated cells. Clinically, the serum levels of beta-MG are increased in patients with renal failure, immune disorders, and various malignant diseases. In this study, the serum levels of beta-MG were measured clinically for a total of 114 cases. Diverse conditions were ensured by biopsy except for 10 control cases, and the following eight groups were diversified: (1) control group, 10 cases; (2) oral carcinoma, 36 cases; (3) mixed tumor, 7 cases; (4) pyogenic granuloma, 12 cases; (5) leukoplakia, 18 cases; (6) mucocele, 15 cases; (7) ameloblastoma, 7 cases; (8) fibroma, 9 cases. The serum levels of beta-MG in oral cancer and leukoplakia patients were found to be significantly higher compared with that of the control group and patients with benign oral tumors. Further study to unravel the correlations between the clinical stages, the treatment of oral cancer, and beta-MG is now in progress. FAU - Lin, S C AU - Lin SC LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - China (Republic : 1949- ) TA - Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi JT - Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology JID - 8008067 RN - 0 (beta 2-Microglobulin) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Humans MH - Leukoplakia, Oral/blood MH - Middle Aged MH - Mouth Neoplasms/*blood MH - beta 2-Microglobulin/*analysis EDAT- 1986/08/01 00:00 MHDA- 1986/08/01 00:01 CRDT- 1986/08/01 00:00 PHST- 1986/08/01 00:00 [pubmed] PHST- 1986/08/01 00:01 [medline] PHST- 1986/08/01 00:00 [entrez] PST - ppublish SO - Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1986 Aug;19(3):183-8.