PMID- 35463544
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230402
IS  - 0377-1237 (Print)
IS  - 2213-4743 (Electronic)
IS  - 0377-1237 (Linking)
VI  - 78
IP  - 2
DP  - 2022 Apr
TI  - Efficacy of early structured pulmonary rehabilitation program in pulmonary 
      function, exercise capacity, and health-related quality of life for patients with 
      post-tubercular sequelae: A pilot study.
PG  - 164-169
LID - 10.1016/j.mjafi.2020.09.001 [doi]
AB  - BACKGROUND: Residual structural changes in the lung along with pulmonary 
      impairment remain in a large number of patients of tuberculosis after 
      microbiological cure. The aim of this study was to determine whether 12 weeks of 
      a structured pulmonary rehabilitation program (PRP) administered along with 
      antitubercular treatment improved the baseline measurement of pulmonary function, 
      exercise capacity, and health-related quality of life (HRQOL). METHODS: A pilot 
      study with single blind randomized control design was carried out in a tertiary 
      care chest center. Spirometry, exercise capacity by 6-minute walk distance 
      (6MWD), and HRQOL using St George respiratory questionnaire (SGRQ) score were 
      evaluated in 62 patients, divided into 2 groups: intervention group (IG) (n = 31) 
      and control group (CG) (n = 31) patients at baseline and at end of 12 weeks. IG 
      completed 12 weeks of PRP. RESULTS: Significant difference in forced expiratory 
      volume in 1st second (FEV1) (2.94 L at baseline vs 3.18 L at end of 12 weeks of 
      PRP, diff 0.239 L, p-0.001), forced vital capacity (FVC) (3.43 L vs 3.75L, p 
      -0.00), 6MWD (440.6 m vs 574.6 m, p = 0.00), and SGRQ score of at baseline 
      (24.5 m vs 11.1m, p = 0.00) was seen in the IG. At end of 12 weeks, there was 
      statistically significant difference in FEV1(L) (p = 0.01, 95% CI -0.317 to 
      -0.046), FVC(L) (p = 0.00, 95% CI -0.359 to -0.139),6MWD(m) (p = 0.00; 95% CI 
      -101.6 to -49.57) between CG and IG. There was no statistically significant 
      difference in SGRQ scores between the 2 groups (p = 0.231). CONCLUSION: PRP 
      administered along with treatment is beneficial in reducing residual pulmonary 
      impairment.
CI  - (c) 2022 Director General, Armed Forces Medical Services. Published by Elsevier, a 
      division of RELX India Pvt. Ltd.
FAU - Ahmed, Safia
AU  - Ahmed S
AD  - Associate Professor (Respiratory Medicine), Command Hospital (Air Force), 
      Bengaluru, India.
FAU - Sharma, Neeraj
AU  - Sharma N
AD  - Graded Specialist (Respiratory Medicine), Command Hospital (EC), Kolkata, India.
FAU - Patrikar, Seema
AU  - Patrikar S
AD  - Statistician, Department of Community Medicine, Armed Forces Medical College, 
      Pune, India.
FAU - Samiullah
AU  - Samiullah
AD  - Junior Physiotherapist, Army Institute of Cardio-thoracic Sciences (AICTS), Pune, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20201118
PL  - India
TA  - Med J Armed Forces India
JT  - Medical journal, Armed Forces India
JID - 7602492
PMC - PMC9023554
OTO - NOTNLM
OT  - 6-minute walk distance (6MWD)
OT  - Health-related quality of life (HRQOL)
OT  - Pulmonary rehabilitation
OT  - Pulmonary tuberculosis
COIS- The authors have none to declare
EDAT- 2022/04/26 06:00
MHDA- 2022/04/26 06:01
PMCR- 2023/04/01
CRDT- 2022/04/25 05:21
PHST- 2019/07/14 00:00 [received]
PHST- 2020/09/01 00:00 [accepted]
PHST- 2022/04/25 05:21 [entrez]
PHST- 2022/04/26 06:00 [pubmed]
PHST- 2022/04/26 06:01 [medline]
PHST- 2023/04/01 00:00 [pmc-release]
AID - S0377-1237(20)30172-6 [pii]
AID - 10.1016/j.mjafi.2020.09.001 [doi]
PST - ppublish
SO  - Med J Armed Forces India. 2022 Apr;78(2):164-169. doi: 
      10.1016/j.mjafi.2020.09.001. Epub 2020 Nov 18.