PMID- 35464259
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 15
DP  - 2022
TI  - The Relationship Between Depression and Multifactorial Control and Microvascular 
      Complications in Vietnamese with Type 2 Diabetes Mellitus Aged 30-60 Years.
PG  - 1185-1195
LID - 10.2147/DMSO.S354443 [doi]
AB  - BACKGROUND: Depression is a common mental disorder in people with type 2 diabetes 
      mellitus (T2DM). Depression and T2DM have a reciprocal interaction through many 
      factors, of which the most important is the multifactorial control and 
      microvascular complications of T2DM. AIM: This research aims to determine the 
      rate of depression and the association between depression and multifactorial 
      control and microvascular complications in patients with T2DM aged 30-60 years in 
      Vietnam. METHODS: A cross-sectional and descriptive study was conducted on 231 
      outpatients with T2DM at Bach Mai hospital, Hanoi, Vietnam. Depression severity 
      was measured with the Patient Health Questionnaire-9 (PHQ-9). RESULTS: The rate 
      of depression in patients with T2DM aged 30-60 years was 16.9% (in which, the 
      rate of mild depression was 15.2% and moderate depression was 1.7%; no serious 
      depression). The prevalence of depression was higher in female patients than in 
      male patients (p = 0.049). There is a statistically significant difference in the 
      rate of depression by age, duration of diabetes, and treatment method for type 2 
      diabetes. Poor HbA1c control and microvascular complications increase the risk of 
      depression (OR = 2.37; 95% CI 1.11-5.02, p = 0.033 and OR = 2.62; 95% CI 
      1.15-5.93, p = 0.027, respectively). When the multivariate analysis was 
      performed, it was shown that sex, treatment for glycemic control, and 
      microvascular complications had a statistically significant influence on PHQ-9 
      score. CONCLUSION: In Vietnam, there are 16.9% of patients with T2DM aged 30-60 
      years suffer from depression. Poor HbA1c control, the presence of microvascular 
      complications, and without antihyperglycemic treatment increase the risk of 
      developing depression.
CI  - (c) 2022 Dinh Le et al.
FAU - Dinh Le, Tuan
AU  - Dinh Le T
AUID- ORCID: 0000-0003-2633-583X
AD  - Center of Emergency, Critical Care Medicine and Clinical Toxicology, Military 
      Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
AD  - Department of Rheumatology and Endocrinology,Military Hospital 103, Vietnam 
      Military Medical University, Hanoi, Vietnam.
FAU - Huy Duong, Hoang
AU  - Huy Duong H
AUID- ORCID: 0000-0002-9125-6006
AD  - Department of Neurology, Thai Binh University of Medicine and Pharmacy, Thai 
      Binh, Vietnam.
FAU - Thi Nguyen, Ly
AU  - Thi Nguyen L
AD  - Department of Internal Medicine, Thai Binh University of Medicine and Pharmacy, 
      Thai Binh, Vietnam.
AD  - Postgraduate Student, Department of Internal Medicine, Hanoi Medical University, 
      Hanoi, Vietnam.
FAU - Phi Thi Nguyen, Nga
AU  - Phi Thi Nguyen N
AD  - Department of Rheumatology and Endocrinology,Military Hospital 103, Vietnam 
      Military Medical University, Hanoi, Vietnam.
FAU - Tien Nguyen, Son
AU  - Tien Nguyen S
AUID- ORCID: 0000-0002-3220-234X
AD  - Department of Rheumatology and Endocrinology,Military Hospital 103, Vietnam 
      Military Medical University, Hanoi, Vietnam.
FAU - Van Ngo, Manh
AU  - Van Ngo M
AD  - Postgraduate Training Management Department, Thai Binh University of Medicine and 
      Pharmacy, Thai Binh, Vietnam.
LA  - eng
PT  - Journal Article
DEP - 20220418
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC9031987
OTO - NOTNLM
OT  - depression
OT  - microvascular complications
OT  - multifactorial control
OT  - type 2 diabetes mellitus aged 30-60 years
COIS- The authors declared no potential conflicts of interest concerning the research, 
      authorship, and/or publication of this article.
EDAT- 2022/04/26 06:00
MHDA- 2022/04/26 06:01
PMCR- 2022/04/18
CRDT- 2022/04/25 05:30
PHST- 2021/12/24 00:00 [received]
PHST- 2022/04/01 00:00 [accepted]
PHST- 2022/04/25 05:30 [entrez]
PHST- 2022/04/26 06:00 [pubmed]
PHST- 2022/04/26 06:01 [medline]
PHST- 2022/04/18 00:00 [pmc-release]
AID - 354443 [pii]
AID - 10.2147/DMSO.S354443 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2022 Apr 18;15:1185-1195. doi: 10.2147/DMSO.S354443. 
      eCollection 2022.