PMID- 35466548
OWN - NLM
STAT- MEDLINE
DCOM- 20220622
LR  - 20220716
IS  - 1473-2165 (Electronic)
IS  - 1473-2130 (Print)
IS  - 1473-2130 (Linking)
VI  - 21
IP  - 6
DP  - 2022 Jun
TI  - Development of customized inner beauty products and customized cosmetics apps 
      according to the use of NRF2 through DTC genetic testing after the COVID-19 
      pandemic.
PG  - 2288-2297
LID - 10.1111/jocd.14467 [doi]
AB  - BACKGROUND: After the coronavirus disease-19 (COVID-19) pandemic, the definition 
      of health continuity, well-being, and well-dying is also evolving. OBJECTIVES: 
      This review is about the utilization of nuclear factor erythroid 2-related factor 
      2 (NRF2) for customized inner beauty products and customized cosmetics through 
      Direct-To-Consumer (DTC) genetic testing in the non-face-to-face era that is 
      evolving after the global pandemic. METHODS: In May 2021, we proposed a narrative 
      review as a new report and commentary. It was written with reference to keywords 
      such as "Covid DTC Genetic Test," "Covid 4th industrial revolution," "Covid 
      NRF2," and "Antioxidants." This study was performed by searching on PubMed, 
      Google Scholar, Scopus, and ResearchGate. A total of 432 papers were retrieved, 
      of which 40 were successfully included in this study. RESULTS: With the rapid 
      transition to a non-face-to-face society after COVID-19, the concept of DTC was 
      born, which allows consumers to receive genetic testing directly without visiting 
      a medical institution. Based on the 4th industrial revolution, a convergence 
      medical device is needed to secure the function as an NRF2 regulator of 
      antioxidants in customized inner beauty products and customized cosmetics. 
      CONCLUSION: Therefore, let us look at the fact that a fusion medical device based 
      on the 4th industrial revolution has emerged in the global DTC genetic test 
      market, which is still insufficient to summarize important research results. This 
      study is expected to be an important data for the development of antioxidants as 
      NRF2 regulators in customized inner beauty products and customized cosmetics. As 
      mobile use increases in the future, additional research focusing on app 
      development is needed, and various follow-up studies are also needed.
CI  - (c) 2022 Wiley Periodicals LLC.
FAU - Lee, Jinkyung
AU  - Lee J
AD  - Division of Beauty Arts Care, Department of Practical Arts, Graduate School of 
      Culture and Arts, Dongguk University, Seoul, Republic of Korea.
AD  - Daily Beauty Unit, Amorepacific Co., Seoul, Republic of Korea.
FAU - Kwon, Ki Han
AU  - Kwon KH
AD  - College of General Education, Kookmin University, Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220424
PL  - England
TA  - J Cosmet Dermatol
JT  - Journal of cosmetic dermatology
JID - 101130964
RN  - 0 (Antioxidants)
RN  - 0 (Cosmetics)
RN  - 0 (NF-E2-Related Factor 2)
SB  - IM
MH  - Antioxidants
MH  - Beauty
MH  - *COVID-19
MH  - *Cosmetics
MH  - Genetic Testing/methods
MH  - Humans
MH  - NF-E2-Related Factor 2/genetics
MH  - Pandemics
PMC - PMC9115250
OTO - NOTNLM
OT  - 4th industrial revolution
OT  - COVID-19
OT  - DTC genetic test
OT  - NRF2
OT  - antioxidants
OT  - customized cosmetics
COIS- The authors of this manuscript do not have any conflicts of interest to disclose.
EDAT- 2022/04/26 06:00
MHDA- 2022/06/23 06:00
PMCR- 2022/04/24
CRDT- 2022/04/25 06:16
PHST- 2022/04/02 00:00 [revised]
PHST- 2021/08/07 00:00 [received]
PHST- 2021/09/08 00:00 [accepted]
PHST- 2022/04/26 06:00 [pubmed]
PHST- 2022/06/23 06:00 [medline]
PHST- 2022/04/25 06:16 [entrez]
PHST- 2022/04/24 00:00 [pmc-release]
AID - JOCD14467 [pii]
AID - 10.1111/jocd.14467 [doi]
PST - ppublish
SO  - J Cosmet Dermatol. 2022 Jun;21(6):2288-2297. doi: 10.1111/jocd.14467. Epub 2022 
      Apr 24.