PMID- 3546967
OWN - NLM
STAT- MEDLINE
DCOM- 19870406
LR  - 20041117
IS  - 0302-2137 (Print)
IS  - 0302-2137 (Linking)
VI  - 64
IP  - 6
DP  - 1986
TI  - A possible biological function of carbohydrate structures which are typical of 
      erythrocytes.
PG  - 331-4
AB  - Carbohydrates of erythrocyte glycoconjugates seem to be specifically designed so 
      that they do not appreciably interact with other types of cells or ligands. This 
      applies to glycosphingolipids (GSLs) and glycoproteins (GPs). An important 
      distinction between the two types of glycoconjugates seems to be that GPs, apart 
      from carrying carbohydrates, have some biological function which is most likely 
      associated with their protein moieties. GSLs of erythrocytes, including the ABH, 
      PP1 and Pk blood group substances, are viewed as energetically cheap 
      membrane-packing substances filling in the membrane areas not covered by 
      functional GPs. Their sole function should be the formation of inert carbohydrate 
      protective layer at the membrane. The role of the inert carbohydrate structures 
      in the development, tumorigenesis and evolution of blood group polymorphism is 
      discussed.
FAU - Koscielak, J
AU  - Koscielak J
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Finland
TA  - Med Biol
JT  - Medical biology
JID - 0417300
RN  - 0 (Blood Group Antigens)
RN  - 0 (Glycoproteins)
RN  - 0 (Glycosphingolipids)
SB  - IM
MH  - Animals
MH  - Blood Group Antigens
MH  - Diet
MH  - Erythrocyte Membrane/*analysis
MH  - Glycoproteins/analysis/*physiology
MH  - Glycosphingolipids/analysis/*physiology
MH  - Humans
MH  - Polymorphism, Genetic
RF  - 24
EDAT- 1986/01/01 00:00
MHDA- 1986/01/01 00:01
CRDT- 1986/01/01 00:00
PHST- 1986/01/01 00:00 [pubmed]
PHST- 1986/01/01 00:01 [medline]
PHST- 1986/01/01 00:00 [entrez]
PST - ppublish
SO  - Med Biol. 1986;64(6):331-4.