PMID- 35472247 OWN - NLM STAT- MEDLINE DCOM- 20221108 LR - 20221207 IS - 2042-7174 (Electronic) IS - 0961-7671 (Linking) VI - 30 IP - 5 DP - 2022 Nov 4 TI - A randomized controlled trial of a pharmacist-led intervention to enhance knowledge of Vietnamese patients with type 2 diabetes mellitus. PG - 449-456 LID - 10.1093/ijpp/riac030 [doi] AB - OBJECTIVES: We aimed to assess whether a pharmacist-led intervention enhances knowledge, medication adherence and glycemic control in patients with type 2 diabetes mellitus (T2DM). METHODS: We conducted a single-blinded randomized controlled trial in Vietnam. Individuals with T2DM were recruited from a general hospital and randomly allocated to intervention and routine care. The intervention group received routine care plus counselling intervention by a pharmacist, including providing drug information and answering individual patients' queries relating to T2DM and medications, which had not been done in routine care. We assessed the outcomes: knowledge score as measured by the Diabetes Knowledge Questionnaire, self-reported adherence and fasting blood glucose (FBG) at the 1-month follow-up. KEY FINDINGS: A total of 165 patients (83 intervention, 82 control) completed the study; their mean age was 63.33 years, and 49.1% were males. The baseline characteristics of the patients were similar between the groups. At 1-month follow-up, the pharmacist's intervention resulted in an improvement in all three outcomes: knowledge score [B = 5.527; 95% confidence intervals (CI): 3.982 to 7.072; P < 0.001], adherence [odds ratio (OR) = 9.813; 95% CI: 2.456 to 39.205; P = 0.001] and attainment of target FBG (OR = 1.979; 95% CI: 1.029 to 3.806; P = 0.041). CONCLUSIONS: The pharmacist-led intervention enhanced disease knowledge, medication adherence and glycemic control in patients with T2DM. This study provides evidence of the benefits of pharmacist counselling in addition to routine care for T2DM outpatients in a Vietnam population. CI - (c) The Author(s) 2022. Published by Oxford University Press on behalf of the Royal Pharmaceutical Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. FAU - Nguyen, Thao H AU - Nguyen TH AD - Department of Clinical Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. FAU - Tran, Tam T T AU - Tran TTT AD - Faculty of Pharmacy, Hau Giang General Hospital, Hau Giang Province, Vietnam. FAU - Nguyen, Nguyet K AU - Nguyen NK AD - Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam. FAU - Diep, Han G AU - Diep HG AD - Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam. FAU - Vo, Son D AU - Vo SD AD - Faculty of Pharmacy, Hau Giang General Hospital, Hau Giang Province, Vietnam. FAU - Taxis, Katja AU - Taxis K AD - Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands. FAU - Pham, Suol T AU - Pham ST AD - Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam. FAU - Nguyen, Thang AU - Nguyen T AUID- ORCID: 0000-0001-7799-4523 AD - Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam. LA - eng PT - Journal Article PT - Randomized Controlled Trial PL - England TA - Int J Pharm Pract JT - The International journal of pharmacy practice JID - 9204243 SB - IM MH - Male MH - Humans MH - Middle Aged MH - Female MH - *Diabetes Mellitus, Type 2/drug therapy MH - Pharmacists MH - Vietnam MH - Medication Adherence MH - Asian People OTO - NOTNLM OT - Vietnam OT - knowledge OT - pharmacist-led intervention OT - type 2 diabetes mellitus EDAT- 2022/04/27 06:00 MHDA- 2022/11/09 06:00 CRDT- 2022/04/26 17:20 PHST- 2021/08/26 00:00 [received] PHST- 2022/03/22 00:00 [accepted] PHST- 2022/04/27 06:00 [pubmed] PHST- 2022/11/09 06:00 [medline] PHST- 2022/04/26 17:20 [entrez] AID - 6574472 [pii] AID - 10.1093/ijpp/riac030 [doi] PST - ppublish SO - Int J Pharm Pract. 2022 Nov 4;30(5):449-456. doi: 10.1093/ijpp/riac030.